Social wellbeing
Laughter Yoga / Therapy
Laughter Yoga / Therapy is a group-based social-wellness practice. Research has focused most on emotional wellbeing and stress-related themes, with additional work examining pain and physical-health outcomes.
Its studied outcomes include blood glucose support, physical endurance, and mood improvement.
Overview
Laughter Yoga / Therapy is a group-based social-wellness practice. Research has focused most on emotional wellbeing and stress-related themes, with additional work examining pain and physical-health outcomes. The literature spans general wellness outcomes as well as proposed uses for specific medical conditions.
The overall picture differs by area: evidence is more developed for general emotional and stress-related themes than for condition-specific uses, where support remains limited. These findings describe areas of study rather than establishing Laughter Yoga / Therapy as a treatment for any medical condition.
Well researched: 35 studies. Last checked Oct 9, 2026.
- 25
- human evidence
- 8
- eligible
- 9
- unclassified
- 1
- animal / null result
Best-evidenced uses
- Stress Resilience ImprovementMedium · Meta-analysis
- Analgesic EffectMedium · Meta-analysis
- Anxiety ReductionMedium · Meta-analysis
- 35
- Studies
Evidence checked Oct 9, 2026 · newest study 2026
- A
- 2
- B
- 7
- C
- 25
- D
- 1
68 community reports across 4 platforms
Coverage
- Effects
- 32
- Helps with
- 11
- Side effects
- 3
- Interactions
- 9
How to read the evidence
Evidence tier — overall strength of the evidence for the whole compound
- StrongWell established — backed by strong, consistent human research.
- ModerateSome genuine support, but mostly from small or lower-quality studies. Promising, not proven.
- PreliminaryEarly-stage evidence — a promising hypothesis, not an established effect yet.
- LimitedVery limited evidence — treat this as a hypothesis, not proof.
- InsufficientNot enough good evidence to draw conclusions yet.
Certainty — how sure we can be that the effect is real
- Very highVery sure — strong, consistent evidence
- HighFairly sure — consistent evidence from good studies
- MediumModerately sure — new studies could change this
- LowNot sure — little or mixed evidence
- Very lowVery unsure — almost no usable evidence
Source — where the data comes from
- Meta-analysisPooled analysis of many trials — the strongest evidence
- RCTRandomized controlled trial — a strong human study design
- ClinicalA human clinical study
- Reference knowledgeFrom general health-science or pharmacology references, not a study of this exact claim
- Animal researchStudied in animals, not humans
- Community reportsAggregated user reports — anecdotal signal, not evidence
- TheoreticalMechanism-based reasoning, not yet tested
Study grade — quality of each underlying study (A best, D weakest)
- AHigh-quality — strong, consistent human trials
- BGood — solid evidence with some limitations
- CModerate — limited, small, or mixed-quality studies
- DWeak — preliminary, indirect, or animal-only
Confidence — how strongly the sources back a finding
A 0–100 score from study quality and agreement
Most supplement evidence is graded C–D. Read it as preliminary signal, not proof.
These are research findings, not promises. A practice does not replace medical treatment.
What does research say?
What studies found for each claimed effect, best evidence first.
32 claims:8 some evidence4 mixed13 not enough evidence5 not tested in people1 personal stories only1 no benefit found
Stress Resilience ImprovementSome evidence it helpsSize of effect: Large
Some human studies found a benefit. More research could change this.
13 of 17 studies found a benefit; 4 found none. Strongest study: a pooled analysis of several trials. Trials that found it ran as little as 4 weeks, typically 5.
A meta-analysis of randomized trials found reduced stress. The studies included people with conditions such as cancer, anxiety disorders, and type 2 diabetes.
Open the Stress Resilience Improvement pageAnalgesic EffectSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
All 9 studies with a clear result found a benefit. Strongest study: a pooled analysis of several trials. Trials that found it ran as little as 2 weeks, typically 4.
Meta-analyses of randomized trials reported improvement in pain among people with cancer; one review also described benefits for people with chronic kidney disease, eczema, leukemia, and lymphoma. The abstracts did not name the pain measurement scale.
Open the Analgesic Effect pageAnxiety ReductionSome evidence it helpsSize of effect: Medium
Some human studies found a benefit. More research could change this.
14 of 16 studies found a benefit; 2 found none. Strongest study: a pooled analysis of several trials. Trials that found it ran as little as 2 weeks, typically 7.
A meta-analysis of randomized trials found reduced anxiety. The studies included people with anxiety disorders, depression, cancer, and other health conditions.
Open the Anxiety Reduction pageNausea Relief SupportSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
All 3 studies with a clear result found a benefit. Strongest study: a randomized controlled trial. Trials that found it ran as little as 2 weeks, typically 3.
A systematic review of randomized trials found lower nausea-vomiting severity among 1,127 people in its analysis of this outcome. The evidence came from people with cancer, leukemia, or lymphoma.
Open the Nausea Relief Support pagePhysical FunctionSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
All 4 studies with a clear result found a benefit. Strongest study: a randomized controlled trial. Trials that found it ran as little as 4 weeks, typically 8.
Open the Physical Function pagePhysical Endurance IncreaseSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
All 2 studies with a clear result found a benefit. Strongest study: a randomized controlled trial.
In a randomized trial involving 80 people with cancer, the laughter yoga group showed higher exercise capacity than the comparison group.
Open the Physical Endurance Increase pageBlood Glucose Level SupportSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
All 3 studies with a clear result found a benefit. Strongest study: a randomized controlled trial.
In a 2023 randomized trial of 42 people with type 2 diabetes, mean HbA1c changed from 7.07% to 6.82% with Laughter Yoga, compared with 7.19% to 7.26% in the control group; the between-group difference was −0.31% (95% confidence interval: −0.54% to −0.09%). A 2026 quasi-experimental study also reported a reduction in fasting blood sugar.
Open the Blood Glucose Level Support pageLung Capacity ImprovementSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
All 3 studies with a clear result found a benefit. Strongest study: a systematic review of studies.
Open the Lung Capacity Improvement page
What to expect
The findings focus on programmes over weeks rather than immediate effects from a first session. Benefits were measured by the end of programmes lasting as little as 2 weeks, while typical trial durations ranged from 4 to 8 weeks, depending on the outcome. These timelines describe when changes were measured in trials, not a guaranteed schedule for when an individual will notice them.
Also studied in people with 11 health conditions
How strong the evidence is in each group. This is research, not a treatment recommendation.
DepressionSome evidence it helpsSize of effect: Not known
Some human studies found a benefit. More research could change this.
5 of 6 studies found a benefit; 1 found none.
A pooled analysis of 33 randomized trials found a reduction in depression scores. A review also reported decreased depression and anxiety following laughter yoga.
Open the Depression pageMetabolic SyndromeNot enough evidence
Too few or too small studies to know if it works.
The one study found a benefit.
A 2022 randomized controlled trial involving 235 people with Metabolic Syndrome found improvements in body weight, BMI, stress, well-being and health-related quality of life.
Open the Metabolic Syndrome pageChronic PainNot enough evidence
Too few or too small studies to know if it works.
All 2 studies with a clear result found a benefit.
A review reported alleviation of pain and fatigue in children, including children with cancer.
Open the Chronic Pain pageAutism Spectrum DisorderNot enough evidence
Too few or too small studies to know if it works.
The one study found a benefit.
A review's narrative synthesis reported improved anxiety in children with high-functioning autism spectrum disorder, drawing on few studies.
Open the Autism Spectrum Disorder pageDiabetes Type 2Not enough evidence
Too few or too small studies to know if it works.
The one study found a benefit.
A 2023 randomized controlled trial involving 42 people with Diabetes Type 2 found a reduction in HbA1c after a 12-week laughter yoga program.
Open the Diabetes Type 2 pageLung CancerNot enough evidence
Too few or too small studies to know if it works.
The one study found a benefit.
A 2023 randomized controlled trial involving 80 people with Lung Cancer found improvements in stress, psychological capital and exercise capacity.
Open the Lung Cancer pageParkinson's DiseaseNot enough evidence
Too few or too small studies to know if it works.
The one study found a benefit.
In a trial of 94 participants selected for anxiety or depression, the laughter-yoga group had lower HAMA and HAMD scores than usual care after the intervention.
Open the Parkinson's Disease pageTuberculosisNot enough evidence
Too few or too small studies to know if it works.
The one study found a benefit.
In a 2022 quasi-experimental study, 52 hospitalized people with Tuberculosis who received 8-week simulated laughter therapy showed improvements in pulmonary function, physical symptoms, depression and health-related quality of life.
Open the Tuberculosis page
Before you try it
What studies and reports say about side effects and who it may not suit.
- Side effects
With weak evidence: Fainting (Syncope), Hyperventilation, and Dizziness.
- May not suit you if you have
- Angina, Recent Heart Attack (MI), Post-Surgery Recovery, Acute Febrile Illness, Recent Stroke, Retinal Detachment, and 3 more
- Some trials left out people with
- Epilepsy, Glaucoma, Hypertension (High Blood Pressure), and Diabetes (General)
- Reported by users
- Muscle Ache (Myalgia) and Muscle Strain
General wellness information, not medical advice. Ask a doctor before you start, especially if you take medicines or have a health condition.
How people do it
A gentle start, then what the studies used.
- Start with
- 25 minutes, weekly (Clinical Short-Form Laughter Yoga)A gentle start based on the easiest variation, not on a study.
- Build up to
- 40 minutes, 2 times a week, low intensity (what the studies used)
- What the studies ran
- 88 minutes a week for 6 weeks
- Longest session studied
- 60 minutes (Online Virtual Laughter Yoga)Not a target and not a safe limit: past it there is no evidence either way.
The expert view shows every study, dose protocol and source.
Effects
32 listedStart here
Most likely to help, from the evidence we have
- →Stress Resilience ImprovementCertaintyMediumSourceMeta-analysisLarge effectlong-term17 cited studies
A meta-analysis of randomized trials found reduced stress (SMD = -0.68; 95% CI: -1.02 to -0.33). The studies included people with conditions such as cancer, anxiety disorders, and type 2 diabetes.
What the sources found
13 positive · 4 neutral · 0 negativeconfidence 59/100
How big is the effect
Large effectA big difference on average. Check how strong the evidence is.
Rating adjusted
Lowered from High to Medium after checking study quality: journal, risk of bias, trial size and design.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Cancer (General)
- Chronic Kidney Disease
- Depression
- Diabetes Type 2
- Eczema
- +2 more
Where the evidence comes from
- Article17
Protocol behind this outcome
7 protocolsEstimatedWhat the studies reporting this result did.
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials9 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 35 min 40 min How often 1×/week 2×/week Per week 40 min 75 min Trials that found no benefit ran3 trials and meta-analyses
Smallest Typical How often 1×/week 2×/week Course 4 weeks 8 weeks Timing
Trials that found it ran as little as 4 weeks, typically 5
Open Stress Resilience ImprovementShow studies (17)
Meta-analysisApositive75% confidence2026stress (SMD = -0.68; 95% CI: -1.02 to -0.33)
SMD -0.68 [-1.02, -0.33]Moderate effectTop journalPooled RCTsMeta-analysisApositive60% confidence2025The results showed that laughter therapy can effectively improve cancer patients' stress... (stress scale not named in abstract)
Top journalPooled RCTsMain outcomeInactive controlMeta-analysisBpositiven=134470% confidence2026laughter intervention significantly reduced stress (SMD = -1.41, 95% CI: -2.04, -0.78; p < 0.001), although high heterogeneity was observed (I² = 95.8%).
SMD -1.41 [-2.04, -0.78]Large effectTop journalSome bias concernsPooled RCTsStudies disagree (I² 96%)Main outcomeOpen-labelNo control groupSystematic reviewBpositiven=112735% confidence2026It may also lead to an important reduction in pain, and in stress (low certainty).
Top journalSome bias concernsPooled RCTsStudies disagreeSystematic reviewCpositiven=61760% confidence2024Stress levels, evaluated using different measurement tools, decrease with laughter yoga.
Top journalSome bias concernsMain outcomeOpen-label+11 more in SourcesSystematic reviewCpositiven=30560% confidence2026Findings indicated that laughter yoga contributed to a reduction in anxiety and stress levels in children (p < 0.05)
Top journalSome bias concernsMain outcomeOpen-label - →Analgesic EffectCertaintyMediumSourceMeta-analysis9 cited studies
Meta-analyses of randomized trials reported improvement in pain among people with cancer; one review also described benefits for people with chronic kidney disease, eczema, leukemia, and lymphoma. The abstracts did not name the pain measurement scale.
What the sources found
9 positive · 0 neutral · 0 negativeconfidence 53/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Cancer (General)
- Chronic Kidney Disease
- Eczema
- Leukemia
- Lymphoma
Where the evidence comes from
- Article9
Protocol behind this outcome
5 protocolsEstimatedWhat the studies reporting this result did.
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials4 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 25 min 43 min How often 1×/week 1.5×/week Per week 25 min 60 min Timing
Trials that found it ran as little as 2 weeks, typically 4
Open Analgesic EffectShow studies (9)
Meta-analysisApositive60% confidence2025The results showed that laughter therapy can effectively improve cancer patients'... pain (scale not named in abstract)
Top journalPooled RCTsInactive controlSystematic reviewBpositiven=112735% confidence2026It may also lead to an important reduction in pain, and in stress (low certainty).
Top journalSome bias concernsPooled RCTsStudies disagreeMeta-analysisBpositive55% confidence2024laughter therapy, whether humor or laughter, has a positive effect on anxiety, stress, pain feeling, fatigue, and depression in cancer patients
Pooled RCTsSystematic reviewCpositiven=30560% confidence2026the intervention was reported to alleviate pain, fatigue, and burnout
Top journalSome bias concernsOpen-labelSystematic reviewCpositive35% confidence2024Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.
Laughter Yoga showed patients having improvement in several outcomes such as pain severity
Top journalStudies disagree+3 more in SourcesRCTCpositiven=6960% confidence2023Pre- and post-intervention difference -8.33 ± 11.78 (intervention) vs 0.95 ± 11.39 (control), P = 0.001
MD -9.28Top journalBlinded assessorInactive controlCompleters only - →Anxiety ReductionCertaintyMediumSourceMeta-analysisModerate effect15 cited studies · 2 other sources
A meta-analysis of randomized trials found reduced anxiety (SMD = -0.83; 95% CI: -1.16 to -0.50). The studies included people with anxiety disorders, depression, cancer, and other health conditions.
What the sources found
15 positive · 2 neutral · 0 negativeconfidence 52/100
How big is the effect
Moderate effectA clear difference on average.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Autism Spectrum Disorder
- Cancer (General)
- Chronic Kidney Disease
- Depression
- Eczema
- +3 more
Where the evidence comes from
- Article15
- Expert opinion1
- Community reports1
Protocol behind this outcome
4 protocolsEstimatedWhat the studies reporting this result did.
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials6 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 20 min 43 min How often 1×/week 2×/week Per week 60 min 105 min Timing
Trials that found it ran as little as 2 weeks, typically 7
Open Anxiety ReductionShow studies (17)
Meta-analysisApositive80% confidence2026anxiety (SMD = -0.83; 95% CI: -1.16 to -0.50)
SMD -0.83 [-1.16, -0.5]Large effectTop journalPooled RCTsMeta-analysisApositive60% confidence2025The results showed that laughter therapy can effectively improve cancer patients'... anxiety (scale not named in abstract)
Top journalPooled RCTsMain outcomeInactive controlSystematic reviewBpositiven=112760% confidence2026Laughter therapy probably results in an important reduction in anxiety (SMD: -0.54, 95% CI: -0.84 to -0.24).
SMD -0.54 [-0.84, -0.24]Moderate effectTop journalSome bias concernsPooled RCTsStudies disagreeMeta-analysisBpositiven=54350% confidence2024Laughter therapy could effectively relieve stress, depression and anxiety of cancer patients.
Top journalPooled RCTsInactive controlMeta-analysisBpositiven=15755% confidence2020The Effect of Laughter Therapy on Anxiety: A Meta-analysis.
Laughter therapy can decrease anxiety levels (standardized mean difference = -1.144; 95% CI, -1.950 to -0.338).
SMD -1.14 [-1.95, -0.34]Large effectTop journalMain outcome+11 more in SourcesMeta-analysisBpositive55% confidence2024laughter therapy, whether humor or laughter, has a positive effect on anxiety, stress, pain feeling, fatigue, and depression in cancer patients
Pooled RCTsMain outcome - →Antidepressant EffectCertaintyMediumSourceMeta-analysisLarge effectconflicting findings15 cited studies · 1 other source
A meta-analysis of randomized trials found reduced depression (SMD = -0.9; 95% CI: -1.29 to -0.52), including studies in people with cancer, depression, and other conditions. However, another review judged the evidence on depressive symptoms to be very low certainty.
What the sources found
13 positive · 3 neutral · 0 negativeconfidence 49/100
How big is the effect
Large effectA big difference on average. Check how strong the evidence is.
Why this rating
- A reviewer set it to Medium · curator approved
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Cancer (General)
- Chronic Kidney Disease
- Depression
- Eczema
- Major Depressive Disorder
- +1 more
Where the evidence comes from
- Article15
- Expert opinion1
Protocol behind this outcome
4 protocolsEstimatedWhat the studies reporting this result did.
- Per week
- 105 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials4 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 20 min 33 min How often 2×/week Timing
Trials that found it ran as little as 4 weeks, typically 8
Open Antidepressant EffectShow studies (16)
Meta-analysisApositive82% confidence2026Laughter therapy significantly reduced depression (standardized mean differences [SMD] = -0.9; 95% CI: -1.29 to -0.52)
SMD -0.9 [-1.29, -0.52]Large effectTop journalPooled RCTsMain outcomeMeta-analysisApositive60% confidence2025The results showed that laughter therapy can effectively improve cancer patients'... depression (scale not named in abstract)
Top journalPooled RCTsMain outcomeInactive controlSystematic reviewBneutraln=112715% confidence2026However, the evidence regarding depressive symptoms, fatigue, mood, and vomiting frequency is very uncertain (very low certainty).
Top journalSome bias concernsPooled RCTsStudies disagreeMeta-analysisBpositiven=54350% confidence2024Laughter therapy could effectively relieve stress, depression and anxiety of cancer patients.
Top journalPooled RCTsInactive controlMeta-analysisBpositive55% confidence2024laughter therapy, whether humor or laughter, has a positive effect on anxiety, stress, pain feeling, fatigue, and depression in cancer patients
Pooled RCTs+10 more in SourcesSystematic reviewCpositiven=61750% confidence2024It was concluded that stress and burnout levels, depression and anxiety, salivary cortisol levels decreased especially after laughter yoga.
Top journalSome bias concernsOpen-label - →Nausea Relief SupportCertaintyMediumSourceRCT3 cited studies
A systematic review of randomized trials found lower nausea-vomiting severity among 1,127 people in its analysis of this outcome (MD: -0.45, 95% CI: -0.80 to -0.09; moderate certainty). The evidence came from people with cancer, leukemia, or lymphoma.
What the sources found
3 positive · 0 neutral · 0 negativeconfidence 57/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Rating adjusted
Lowered from High to Medium after checking study quality: journal, risk of bias, trial size and design.
Who was studied
- People with a condition
- Cancer (General)
- Leukemia
- Lymphoma
Where the evidence comes from
- Article3
Protocol behind this outcome
2 protocolsMeasuredWhat the studies reporting this result did.
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials2 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 25 min 35 min How often 1×/week 1.5×/week Per week 25 min 58 min Timing
Trials that found it ran as little as 2 weeks, typically 3
Open Nausea Relief SupportShow studies (3)
Systematic reviewBpositiven=112755% confidence2026nausea-vomiting severity (MD: -0.45, 95% CI: -0.80 to -0.09; moderate certainty)
MD -0.45 [-0.8, -0.09]Top journalSome bias concernsPooled RCTsStudies disagreeRCTCpositiven=6960% confidence2024The intragroup comparison showed a statistically significant decrease in the severity of nausea in the intervention group from pre-test to post-test (P = 0.020)
Main outcomeOpen-labelInactive controlCompleters onlyRCTCpositiven=6055% confidence2025nausea/loss of appetite symptoms were alleviated in the intervention group (p=0.004 for 4th measurement)
Weak journalOpen-labelInactive control - →Physical FunctionCertaintyMediumSourceRCT4 cited studies · 1 other source
A review pooling randomized and non-randomized human studies reported improved gross motor skills. In a randomized trial of 235 people, the physical component summary scores of health-related quality of life improved (p=0.04; MD 1.88 score [-0.08, 3.83]).
What the sources found
5 positive · 0 neutral · 0 negativeconfidence 46/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Autism Spectrum Disorder
- Cancer (General)
- Metabolic Syndrome
Where the evidence comes from
- Article4
- Community reports1
Protocol behind this outcome
2 protocolsMeasuredWhat the studies reporting this result did.
1×/week
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials2 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 25 min 58 min Timing
Trials that found it ran as little as 4 weeks, typically 8
Open Physical FunctionShow studies (5)
Systematic reviewCpositive25% confidence2026improved gross motor skills
RCTBpositiven=23565% confidence2022The comprehensive laughter program significantly improved the physical component summary (PCS) scores of HRQOL (p=0.04)
MD 1.88 [-0.08, 3.83]Top journalOpen-labelInactive controlAllocation not hiddenBorderline p-valueRCTCpositiven=6955% confidence2023mean scores of the role functioning domain in the intervention group (71.08 ± 25.06) was significantly higher than that in the control group (65 ± 76 ± 25.81) (p < 0.05)
MD 6.08Top journalBlinded assessorInactive controlCompleters onlyNarrative reviewCpositiven=31560% confidence2024Physical functioning improved by 0.78 ± 6.08 (p<0.05)
MD 0.78Low-quality journalPooled RCTsOpen-labelInactive controlCommunity reportsmoderate effectpositive25% confidenceThis effect was mentioned in 2 of 31 Reddit reports discussing it.
2 mentions - →Mood ImprovementCertaintyMediumSourceRCTconflicting findingslong-term17 cited studies · 2 other sources
A systematic review pooling randomized and non-randomized human studies found improvements in hope and overall happiness among 305 people in its outcome analysis. Findings about mood are not consistent: another review of randomized trials judged the evidence on mood and depressive symptoms to be very low certainty.
What the sources found
16 positive · 3 neutral · 0 negativeconfidence 50/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Autism Spectrum Disorder
- Cancer (General)
- Chronic Kidney Disease
- Diabetes Type 2
- Eczema
- +2 more
Where the evidence comes from
- Article17
- Expert opinion1
- Community reports1
Protocol behind this outcome
10 protocolsEstimatedWhat the studies reporting this result did.
- Per week
- 78 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials10 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 20 min 40 min How often 1×/week 1.5×/week Timing
Trials that found it ran as little as 4 weeks, typically 5
Open Mood ImprovementShow studies (19)
Systematic reviewBneutraln=112715% confidence2026However, the evidence regarding depressive symptoms, fatigue, mood, and vomiting frequency is very uncertain (very low certainty).
Top journalSome bias concernsPooled RCTsStudies disagreeSystematic reviewCpositiven=30560% confidence2026enhancing hope and overall happiness
Top journalSome bias concernsOpen-labelSystematic reviewCpositive35% confidence2024Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.
Laughter Yoga showed patients having improvement in several outcomes such as subjective well-being
Top journalStudies disagreeSystematic reviewCpositive35% confidence2020significant differences were found in the effectiveness of laughter yoga on ... psychosocial health (life satisfaction, quality of life, loneliness, death anxiety, depression, mood, happiness) in older adults
Main outcomeSystematic reviewCpositive30% confidence2026improved emotional well-being (reduced hopelessness, loneliness, and school burnout)
Studies disagree+13 more in SourcesSystematic reviewCneutral20% confidence2018There is a lack of good quality evidence to show that laughter yoga is more effective than other group-based interventions in improving mental health.
Some bias concernsStudies disagree
Medium probability(5)
- →Physical Endurance IncreaseCertaintyMediumSourceClinical2 cited studies
In a randomized trial involving 80 people with cancer, the laughter yoga group showed higher exercise capacity than the comparison group (Cohen’s d = 0.659; t = 2.947, P < .01).
What the sources found
2 positive · 0 neutral · 0 negativeconfidence 68/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Cancer (General)
- Lung Cancer
Where the evidence comes from
- Article2
Protocol behind this outcome
2 protocolsMeasuredWhat the studies reporting this result did.
30 min · 2×/week
- Course
- 9 weeks
- Per week
- 70 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Physical Endurance IncreaseShow studies (2)
RCTCpositiven=8075% confidence2023However, after the laughter yoga intervention, the difference between the 2 groups was statistically significant (t = 2.947, P < .01), with a large effect size (Cohen’s d = 0.659).
SMD 0.66Moderate effectTop journalMain outcomeBlinded assessorInactive controlCompleters onlyNarrative reviewCpositiven=31560% confidence2024Significantly higher exercise capacity (p<0.01, Cohen's d=0.659)
SMD 0.66Moderate effectLow-quality journalPooled RCTsOpen-labelInactive control - →Blood Glucose Level SupportCertaintyMediumSourceClinical2 cited studies · 1 other source
In a 2023 randomized trial of 42 people with type 2 diabetes, mean HbA1c changed from 7.07% to 6.82% with Laughter Yoga, compared with 7.19% to 7.26% in the control group; the between-group difference was −0.31% (95% confidence interval [CI]: −0.54% to −0.09%). A 2026 quasi-experimental study also reported a reduction in fasting blood sugar.
What the sources found
3 positive · 0 neutral · 0 negativeconfidence 60/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Diabetes Type 2
Where the evidence comes from
- Article2
- Expert opinion1
Protocol behind this outcome
2 protocolsMeasuredWhat the studies reporting this result did.
65 min · 1.5×/week
- Course
- 10 weeks
- Per week
- 85 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Blood Glucose Level SupportShow studies (3)
RCTCpositiven=4270% confidence2023The mean HbA1c levels changed from 7.07% to 6.82% in the laughter yoga group and from 7.19% to 7.26% in the control group. The unadjusted difference between the two groups was statistically significant (−0.31%; 95% confidence interval [CI]: −0.54% to −0.09%; P = 0.008).
MD -0.31 [-0.54, -0.09]Small effectWeak journalMain outcomeBlinded assessorInactive controlQuasi ExperimentalCpositiven=6460% confidence2026significant reductions were observed in fasting blood sugar (P = 0.001)
Weak journalOpen-labelExpert opinionpositive50% confidenceRegular participation in Laughter Yoga improves glycemic control in patients with type 2 diabetes.
Expert knowledge synthesis - →Respiratory Health SupportCertaintyMediumSourceClinical4 cited studies
A review of randomized and non-randomized human studies reported improvement in vital capacity. In a separate quasi-experimental study of 64 people, forced expiratory volume in 1 second (FEV1) increased (P = 0.015); the studies included people with chronic kidney disease or tuberculosis.
What the sources found
3 positive · 1 neutral · 0 negativeconfidence 45/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Chronic Kidney Disease
- Tuberculosis
Where the evidence comes from
- Article4
Protocol behind this outcome
2 protocolsMeasuredWhat the studies reporting this result did.
50 min · 2×/week
- Course
- 8 weeks
- Per week
- 100 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Respiratory Health SupportShow studies (4)
Systematic reviewCpositive35% confidence2024Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.
Laughter Yoga showed patients having improvement in several outcomes such as ... vital capacity
Top journalStudies disagreeQuasi ExperimentalCpositiven=6460% confidence2026forced expiratory volume in 1 second (FEV1) (P = 0.015) ... significantly increased
Weak journalOpen-labelQuasi ExperimentalCpositiven=5260% confidence2022the physical symptom scores significantly decreased from 13.81 (±7.66) at the baseline to 5.88 (±3.50) after the intervention (t = 7.30, p < 0.001)
MD -7.93Low-quality journalMain outcomeOpen-labelInactive controlCompleters onlyQuasi ExperimentalDneutraln=1725% confidence2015There was no change in lung function or blood pressure.
Low-quality journalOpen-labelNo control groupCompleters only - →Lung Capacity ImprovementCertaintyMediumSourceClinicallong-term2 cited studies · 1 other source
A quasi-experimental study of 52 people found pulmonary function increased from 72.85 (±13.71) before the intervention to 77.31 (±12.46) afterward (t = −3.77, p < 0.001; MD 4.46 %). The studies included people with chronic kidney disease or tuberculosis.
What the sources found
3 positive · 0 neutral · 0 negativeconfidence 47/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Chronic Kidney Disease
- Tuberculosis
Where the evidence comes from
- Article2
- Expert opinion1
Open Lung Capacity ImprovementShow studies (3)
Systematic reviewCpositive35% confidence2024Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.
Laughter Yoga showed patients having improvement in several outcomes such as ... vital capacity
Top journalStudies disagreeQuasi ExperimentalCpositiven=5260% confidence2022the experimental group had a statistically significant improvement in pulmonary function from 72.85 (±13.71) before the intervention to 77.31 (±12.46) after the intervention (t = −3.77, p < 0.001)
MD 4.46Low-quality journalMain outcomeOpen-labelInactive controlCompleters onlyExpert opinionpositive45% confidenceThe prolonged exhalations and deep inhalations during laughter yoga exercises engage and strengthen respiratory muscles, improving vital capacity over time.
Expert knowledge synthesis - →Sleep Quality ImprovementCertaintyMediumSourceClinicalconflicting findings10 cited studies · 1 other source
Reviews pooling randomized and non-randomized human studies reported improved sleep quality, but a meta-analysis of randomized trials found no effect on sleep quality. The studies involved people with conditions including anxiety disorders, cancer, and chronic kidney disease.
What the sources found
8 positive · 3 neutral · 0 negativeconfidence 47/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Anxiety Disorder
- Cancer (General)
- Chronic Kidney Disease
- Diabetes Type 2
- Leukemia
- Lymphoma
- +1 more
Where the evidence comes from
- Article10
- Community reports1
Protocol behind this outcome
4 protocolsEstimatedWhat the studies reporting this result did.
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials4 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 25 min 45 min How often 1×/week 2×/week Per week 25 min 90 min Trials that found no benefit ran2 trials and meta-analyses
Smallest Typical Session 20 min 55 min How often 1×/week 4×/week Course 8 weeks 10 weeks Timing
Trials that found it ran as little as 2 weeks, typically 4
Open Sleep Quality ImprovementShow studies (11)
Meta-analysisAneutral50% confidence2025but has no effect on sleep quality (sleep instrument not named in abstract)
Top journalPooled RCTsInactive controlSystematic reviewCpositiven=61745% confidence2024LY has been shown to have a positive effect on general health, improving physical symptoms and sleep disorders, reducing anxiety and depression, and improving social functioning.
Top journalSome bias concernsOpen-labelSystematic reviewCpositive35% confidence2024Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.
Laughter Yoga showed patients having improvement in several outcomes such as sleep quality
Top journalStudies disagreeSystematic reviewCpositive35% confidence2020significant differences were found in the effectiveness of laughter yoga on physical function (blood pressure, cortisol level, sleep quality)
RCTCneutraln=9435% confidence2025There was no significant difference in the PDSS scores between the laughter yoga and control groups (P > 0.05). PDSS post-intervention 120.77 ± 10.55 (LYG) vs 119.17 ± 11.83 (CG), P = 0.501.
Top journalBlinded assessorInactive control+5 more in SourcesRCTCpositiven=9060% confidence2023Laughter yoga significantly improved the resilience levels and sleep quality of the experimental group (P... (Pittsburgh Sleep Quality Index is an inverted instrument; a decrease is an improvement)
Main outcomeInactive control
Low probability(19)
- →Fatigue ReductionCertaintyLowSourceMeta-analysisconflicting findings6 cited studies
Meta-analyses of randomized trials reported improvement in fatigue among people with cancer. Findings conflict: another review judged the evidence on fatigue to be very low certainty.
What the sources found
5 positive · 1 neutral · 0 negativeconfidence 52/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Cancer (General)
- Eczema
Where the evidence comes from
- Article6
Protocol behind this outcome
3 protocolsEstimatedWhat the studies reporting this result did.
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
What worked in trials2 trials and meta-analyses
Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.
Smallest Typical Session 25 min 33 min How often 1×/week 1.2×/week Per week 25 min 43 min Timing
Trials that found it typically ran 4 weeks
Open Fatigue ReductionShow studies (6)
Meta-analysisApositive60% confidence2025The results showed that laughter therapy can effectively improve cancer patients'... and fatigue (scale not named in abstract)
Top journalPooled RCTsInactive controlSystematic reviewBneutraln=112715% confidence2026However, the evidence regarding depressive symptoms, fatigue, mood, and vomiting frequency is very uncertain (very low certainty).
Top journalSome bias concernsPooled RCTsStudies disagreeMeta-analysisBpositive55% confidence2024laughter therapy, whether humor or laughter, has a positive effect on anxiety, stress, pain feeling, fatigue, and depression in cancer patients
Pooled RCTsSystematic reviewCpositiven=30560% confidence2026the intervention was reported to alleviate pain, fatigue, and burnout
Top journalSome bias concernsOpen-labelRCTCpositiven=6960% confidence2023Pre- and post-intervention difference -8.82 ± 22.01 (intervention) vs -0.95 ± 7.31 (control), P < 0.001
MD -7.87Top journalBlinded assessorInactive controlCompleters onlyNarrative reviewCpositiven=31560% confidence2024Fatigue decreased by 8.82 ± 22.01 (p<0.05)
MD -8.82Low-quality journalPooled RCTsOpen-labelInactive control - →Optimism ImprovementCertaintyLowSourceRCT1 cited study
A 2022 randomized trial involving 235 people with metabolic syndrome reported improved mean optimism with a comprehensive laughter program (MD 0.56 score [-0.1, 1.22]).
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 65/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Metabolic Syndrome
Where the evidence comes from
- Article1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
90 min
- Course
- 12 weeks
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Optimism ImprovementShow studies (1)
RCTBpositiven=23565% confidence2022The comprehensive laughter program significantly improved the mean optimism (p=0.03)
MD 0.56 [-0.1, 1.22]Top journalOpen-labelInactive controlAllocation not hiddenBorderline p-value - →Cognitive Function ImprovementCertaintyLowSourceClinical2 cited studies
In a 2019 randomized trial of 56 people with cancer, cognitive functioning scores rose by 5.8 points from baseline to Week 7 in one group and fell by 5.3 points in the other; the between-group difference was 11.1 points [3.2, 19]. A 2024 review also described better cognitive function for a short period after the intervention.
What the sources found
2 positive · 0 neutral · 0 negativeconfidence 60/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Rating adjusted
Lowered from Medium to Low after checking study quality: journal, risk of bias, trial size and design.
Who was studied
- People with a condition
- Cancer (General)
Where the evidence comes from
- Article2
Protocol behind this outcome
2 protocolsMeasuredWhat the studies reporting this result did.
43 min
- Course
- 7 weeks
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Cognitive Function ImprovementShow studies (2)
RCTCpositiven=5660% confidence2019Cognitive functioning score improved by 5.8 points from baseline to Week 7 in Group A, but worsened by 5.3 points in Group B. This resulted in a significant between-group difference that favored Group A over Group B (95% CI: 3.2 to 19.0 points; P = 0.006).
MD 11.1 [3.2, 19]Weak journalOpen-labelNo control groupNarrative reviewCpositiven=31560% confidence2024Intervention group had significantly better cognitive function and less pain than control group for a short period
Low-quality journalPooled RCTsOpen-labelInactive control - →Immune System SupportCertaintyLowSourceClinical1 cited study · 1 other source
A review pooling randomized and non-randomized human studies found increased salivary IgA levels among 305 people in its analysis of this outcome (p < 0.01). This finding concerns a salivary marker, rather than a demonstrated reduction in illness.
What the sources found
2 positive · 0 neutral · 0 negativeconfidence 55/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Cancer (General)
- Eczema
Where the evidence comes from
- Article1
- Expert opinion1
Protocol behind this outcome
1 protocolEstimatedWhat the studies reporting this result did.
40 min · 1.5×/week
- Course
- 5 weeks
- Per week
- 60 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Immune System SupportShow studies (2)
Systematic reviewCpositiven=30560% confidence2026laughter yoga was associated with an increase in salivary IgA levels (p < 0.01)
Top journalSome bias concernsOpen-labelExpert opinionpositive50% confidenceLaughter and positive affect may increase salivary immunoglobulin A (sIgA) and natural killer cell activity, providing a mechanistic basis for immune support.
Expert knowledge synthesis - →Cardiovascular Health SupportCertaintyLowSourceClinical1 cited study · 1 other source
A 2026 quasi-experimental study of 64 healthy participants reported a reduction in heart rate.
What the sources found
2 positive · 0 neutral · 0 negativeconfidence 55/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people
Where the evidence comes from
- Article1
- Expert opinion1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
40 min · 2×/week
- Course
- 8 weeks
- Per week
- 80 min
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Cardiovascular Health SupportShow studies (2)
Quasi ExperimentalCpositiven=6460% confidence2026significant reductions were observed in ... heart rate (P = 0.002)
Weak journalOpen-labelExpert opinionpositive50% confidenceLaughter induces shear stress on vascular endothelium through increased heart rate and cardiac output, improving endothelial function and vasodilation.
Expert knowledge synthesis - →HDL Cholesterol IncreaseCertaintyLowSourceClinical1 cited study
A 2026 quasi-experimental study of 64 healthy participants reported increased high-density lipoprotein levels.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 60/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people
Where the evidence comes from
- Article1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
40 min · 2×/week
- Course
- 8 weeks
- Per week
- 80 min
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open HDL Cholesterol IncreaseShow studies (1)
Quasi ExperimentalCpositiven=6460% confidence2026High-density lipoprotein levels were significantly increased (P = 0.027)
Weak journalOpen-label - →Cholesterol Level ReductionCertaintyLowSourceClinical1 cited study
A 2026 quasi-experimental study of 64 healthy participants reported reduced total cholesterol.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 60/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people
Where the evidence comes from
- Article1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
40 min · 2×/week
- Course
- 8 weeks
- Per week
- 80 min
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Cholesterol Level ReductionShow studies (1)
Quasi ExperimentalCpositiven=6460% confidence2026significant reductions were observed in ... total cholesterol (P = 0.002)
Weak journalOpen-label - →Triglyceride Level ReductionCertaintyLowSourceClinical1 cited study
A 2026 quasi-experimental study of 64 healthy participants reported reduced triglyceride levels.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 60/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people
Where the evidence comes from
- Article1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
40 min · 2×/week
- Course
- 8 weeks
- Per week
- 80 min
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Triglyceride Level ReductionShow studies (1)
Quasi ExperimentalCpositiven=6460% confidence2026significant reductions were observed in ... triglyceride (P = 0.003)
Weak journalOpen-label - →Blood Pressure SupportCertaintyLowSourceClinical3 cited studies
A 2024 review pooling randomized and non-randomized human studies reported improved blood pressure. A 2026 quasi-experimental study in 64 people with chronic kidney disease observed reductions in systolic blood pressure (P = 0.003).
What the sources found
2 positive · 1 neutral · 0 negativeconfidence 40/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Chronic Kidney Disease
Where the evidence comes from
- Article3
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
40 min · 2×/week
- Course
- 8 weeks
- Per week
- 80 min
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Blood Pressure SupportShow studies (3)
Systematic reviewCpositive35% confidence2024Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.
Laughter Yoga showed patients having improvement in several outcomes such as ... blood pressure
Top journalStudies disagreeQuasi ExperimentalCpositiven=6460% confidence2026significant reductions were observed in ... systolic blood pressure (P = 0.003)
Weak journalOpen-labelQuasi ExperimentalDneutraln=1725% confidence2015There was no change in lung function or blood pressure.
MD -1.6 [-1.38, 4.58]Trivial effectLow-quality journalOpen-labelNo control groupCompleters only - →Appetite Increase (Desired)CertaintyLowSourceClinical1 cited study
In a randomized trial involving 60 people with leukemia or lymphoma, nausea and loss-of-appetite symptoms were alleviated in the intervention group (p=0.000 for within-group change).
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 55/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Leukemia
- Lymphoma
Where the evidence comes from
- Article1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
45 min · 2×/week
- Course
- 2 weeks
- Per week
- 90 min
- Supervision
- Instructor-led
A repeated course
Open Appetite Increase (Desired)Show studies (1)
RCTCpositiven=6055% confidence2025nausea/loss of appetite symptoms were alleviated in the intervention group (p=0.000 for within-group change)
Weak journalOpen-labelInactive control - →Skin Health ImprovementCertaintyLowSourceClinical1 cited study
In a randomized trial involving 60 people with leukemia or lymphoma, skin and nail changes were lower in the intervention group than in the control group (p=0.000 for within-group change); hand numbness was also lower.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 55/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Leukemia
- Lymphoma
Where the evidence comes from
- Article1
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
45 min · 2×/week
- Course
- 2 weeks
- Per week
- 90 min
- Supervision
- Instructor-led
A repeated course
Open Skin Health ImprovementShow studies (1)
RCTCpositiven=6055% confidence2025skin and nail changes and the hand numbness in the intervention group were lower than in the control group (p=0.000 for within-group change)
Weak journalOpen-labelInactive control - →Working Memory ImprovementCertaintyLowSourceClinical1 cited study
A review pooling randomized and non-randomized human studies reported enhanced verbal working memory. The reviewed studies included people with anxiety disorders or autism spectrum disorder.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 25/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Autism Spectrum Disorder
Where the evidence comes from
- Article1
Open Working Memory ImprovementShow studies (1)
Systematic reviewCpositive25% confidence2026enhanced verbal working memory
- →Emotional Regulation ImprovementCertaintyLowSourceAnecdotallong-termnot used for recommendations2 other sources
Expert commentary proposes that intentionally generating positive affect through simulated laughter may support emotional regulation by building cognitive and physiological pathways for shifting out of negative moods. Some community members have reported this effect; it has not been established in human studies.
What the sources found
2 positive · 0 neutral · 0 negativeconfidence 36/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
- Community reports1
Why it isn't used for recommendations
No supporting study on file
Open Emotional Regulation ImprovementShow studies (2)
Expert opinionpositive40% confidenceThe intentional practice of generating positive affect through simulated laughter builds the cognitive and physiological pathways for emotional regulation, making it easier to shift out of negative mood states.
Expert knowledge synthesisCommunity reportsmoderate effectpositive31% confidenceThis effect was mentioned in 4 of 55 community reports discussing it (Bluesky 2, Reddit 2).
4 mentions - →Improve Heart Rate Variability (HRV)CertaintyLowSourceTheoreticalnot used for recommendations1 other source
Laughter Yoga is proposed to increase heart rate variability, described as a marker of autonomic flexibility and stress resilience.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 50/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
Why it isn't used for recommendations
No supporting study on file
Open Improve Heart Rate Variability (HRV)Show studies (1)
Expert opinionpositive50% confidenceLaughter Yoga increases heart rate variability, a marker of autonomic flexibility and stress resilience.
Expert knowledge synthesis - →Parasympathetic ActivationCertaintyLowSourceTheoreticalnot used for recommendations1 other source
One proposed explanation is that laughter’s rhythmic diaphragmatic breathing and vagal stimulation may enhance parasympathetic tone and heart rate variability.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 50/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
Why it isn't used for recommendations
No supporting study on file
Open Parasympathetic ActivationShow studies (1)
Expert opinionpositive50% confidenceLaughter induces rhythmic diaphragmatic breathing and vagal stimulation, enhancing parasympathetic tone and heart rate variability.
Expert knowledge synthesis - →Chronic Pain ReductionCertaintyLowSourceTheoreticalnot used for recommendations1 other source
One proposed explanation is that laughter may trigger endorphin release and distract attention from pain, reducing perceived pain intensity in chronic pain conditions.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 50/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
Why it isn't used for recommendations
No supporting study on file
Open Chronic Pain ReductionShow studies (1)
Expert opinionpositive50% confidenceLaughter triggers endorphin release and provides a cognitive distraction from pain, reducing perceived pain intensity in chronic pain conditions.
Expert knowledge synthesis - →Loneliness ReductionCertaintyLowSourceTheoreticalnot used for recommendations1 other source
Group-based Laughter Yoga is proposed to foster shared positive emotional experiences and social bonding, which may reduce feelings of loneliness and social isolation.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 50/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
Why it isn't used for recommendations
No supporting study on file
Open Loneliness ReductionShow studies (1)
Expert opinionpositive50% confidenceGroup-based laughter yoga creates shared positive emotional experiences and social bonding, directly reducing feelings of loneliness and social isolation.
Expert knowledge synthesis - →Detoxification SupportCertaintyLowSourceTheoreticalnot used for recommendations1 other source
One proposed explanation is that the faster, deeper breathing during laughter may support lymphatic flow and gas exchange, aiding metabolic waste clearance.
What the sources found
1 positive · 0 neutral · 0 negativeconfidence 40/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
Why it isn't used for recommendations
No supporting study on file
Open Detoxification SupportShow studies (1)
Expert opinionpositive40% confidenceEnhanced respiratory rate and depth during laughter may support lymphatic flow and gas exchange, aiding in metabolic waste clearance.
Expert knowledge synthesis
Very low probability(1)
- →Weight Management SupportCertaintyVery lowSourceRCTnot used for recommendations1 cited study
A randomized trial in 235 people did not support a weight-management benefit: abdominal circumference did not significantly decrease (MD -0.01 cm [-0.89, 0.87]).
What the sources found
0 positive · 1 neutral · 0 negativeconfidence 60/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Metabolic Syndrome
Where the evidence comes from
- Article1
Why it isn't used for recommendations
Studied, with no positive result
Open Weight Management SupportShow studies (1)
RCTBneutraln=23560% confidence2022There was no significant decrease in abdominal circumference.
MD -0.01 [-0.89, 0.87]Top journalOpen-labelInactive controlAllocation not hidden
What to expect
The findings focus on programmes over weeks rather than immediate effects from a first session. Benefits were measured by the end of programmes lasting as little as 2 weeks, while typical trial durations ranged from 4 to 8 weeks, depending on the outcome. These timelines describe when changes were measured in trials, not a guaranteed schedule for when an individual will notice them.
Conditions it's used for
Complaints and diagnoses people take it for11 listedMost likely to help, from the evidence we have
- →DepressionCertaintyMediumSourceMeta-analysis6 cited studies
A pooled analysis of 33 randomized trials found a reduction in depression scores. A review also reported decreased depression and anxiety following laughter yoga.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Cancer (General)
- Depression
- Eczema
Protocol behind this outcome
4 protocolsEstimatedWhat the studies reporting this result did.
45 min · 2×/week
- Course
- 8 weeks
- Per week
- 90 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open DepressionShow studies (6)
Meta-analysisA70% confidence2026Pooled SMD reduction in depression across 33 RCTs (abstract).
Top journalPooled RCTsSystematic reviewCn=61750% confidence2024Studies reported decreased depression and anxiety following laughter yoga.
Top journalSome bias concernsOpen-labelSystematic reviewCno effectn=30550% confidence2026No statistically significant effect on depression scores in children.
Top journalSome bias concernsOpen-labelSystematic reviewC25% confidence2018Two included experimental studies reported short-term improvement in depressive symptoms; evidence quality weak.
Some bias concernsRCTCn=9155% confidence2025Participants selected for depressive symptoms; laughter yoga reported to reduce depressive symptoms.
Top journalNo control groupRCTCn=6160% confidence2022Significant reduction in depression scores (DASS-42) in nursing students after 4 weeks of online laughter therapy.
Open-labelNo control groupCompleters only
Low probability(10)
- →Metabolic SyndromeCertaintyLowSourceRCT1 cited study
A 2022 randomized controlled trial involving 235 people with Metabolic Syndrome found improvements in body weight, BMI, stress, well-being and health-related quality of life.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Metabolic Syndrome
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
90 min
- Course
- 12 weeks
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Metabolic SyndromeShow studies (1)
RCTBn=23570% confidence2022RCT showing significant improvements in body weight, BMI, stress, well-being, and HRQOL in this population.
Top journalOpen-labelInactive controlAllocation not hidden - →Chronic PainCertaintyLowSourceClinical1 cited study · 1 other source
A review reported alleviation of pain and fatigue in children, including children with cancer.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Cancer (General)
- Eczema
Where the evidence comes from
- Expert opinion
Open Chronic PainShow studies (2)
Systematic reviewCn=30560% confidence2026Studies reported alleviation of pain and fatigue in children, including those with cancer.
Top journalSome bias concernsOpen-labelExpert opinion50% confidenceLaughter yoga is used as a non-pharmacological adjunct for chronic pain management due to its endorphin-releasing, muscle-relaxing, and cognitive-distracting effects.
- →Autism Spectrum DisorderCertaintyLowSourceClinical1 cited study
A review's narrative synthesis reported improved anxiety in children with high-functioning autism spectrum disorder, drawing on few studies.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- Healthy people and patients
- Anxiety Disorder
- Autism Spectrum Disorder
Open Autism Spectrum DisorderShow studies (1)
Systematic reviewC25% confidence2026Narrative synthesis reporting improved anxiety in children with high-functioning autism spectrum disorder; based on few studies.
- →Diabetes Type 2CertaintyLowSourceClinical1 cited study
A 2023 randomized controlled trial involving 42 people with Diabetes Type 2 found a reduction in HbA1c after a 12-week laughter yoga program.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Diabetes Type 2
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
90 min · 1×/week
- Course
- 12 weeks
- Per week
- 90 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Diabetes Type 2Show studies (1)
RCTCn=4270% confidence2023RCT showing significant reduction in HbA1c after 12-week laughter yoga program.
Weak journalBlinded assessorInactive control - →Lung CancerCertaintyLowSourceClinical1 cited study
A 2023 randomized controlled trial involving 80 people with Lung Cancer found improvements in stress, psychological capital and exercise capacity.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Lung Cancer
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
35 min · 2×/week
- Course
- 9 weeks
- Per week
- 70 min
- Intensity
- Low
- Format
- Small group
- Supervision
- Instructor-led
A repeated course
Open Lung CancerShow studies (1)
RCTCn=8075% confidence2023RCT showing significant improvements in stress, psychological capital, and exercise capacity in this population.
Top journalBlinded assessorInactive controlCompleters only - →Parkinson's DiseaseCertaintyLowSourceClinical1 cited study
In a trial of 94 participants selected for anxiety or depression, the laughter-yoga group had lower HAMA and HAMD scores than usual care after the intervention.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Anxiety Disorder
- Depression
- Parkinson's Disease
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
20 min · 7×/week
- Course
- 8 weeks
- Per week
- 140 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open Parkinson's DiseaseShow studies (1)
RCTCn=9450% confidence2025Participants selected for anxiety or depression; the laughter yoga group showed lower HAMA and HAMD scores than usual care at post-intervention.
Top journalBlinded assessorInactive control - →TuberculosisCertaintyLowSourceClinical1 cited study
In a 2022 quasi-experimental study, 52 hospitalized people with Tuberculosis who received 8-week simulated laughter therapy showed improvements in pulmonary function, physical symptoms, depression and health-related quality of life.
How big is the effect
No study gave a number we could compare, so the size is not known.
Who was studied
- People with a condition
- Tuberculosis
Protocol behind this outcome
1 protocolMeasuredWhat the studies reporting this result did.
60 min · 2×/week
- Course
- 8 weeks
- Per week
- 120 min
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Open TuberculosisShow studies (1)
Quasi ExperimentalCn=5260% confidence2022Significant improvements in pulmonary function, physical symptoms, depression, and HRQOL in hospitalized TB patients after 8-week simulated laughter therapy.
Low-quality journalOpen-labelInactive controlCompleters only - →Chronic Fatigue SyndromeCertaintyLowSourceTheoreticalnot used for recommendations1 other source
Gentle, socially engaging activities such as Laughter Yoga are recommended to support mood and mild physical endurance without triggering post-exertional malaise.
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion
Why it isn't used for recommendations
No supporting study on file
Open Chronic Fatigue SyndromeShow studies (1)
Expert opinion50% confidenceGentle, socially engaging activities like Laughter Yoga are recommended to improve mood and mild physical endurance without triggering post-exertional malaise.
- →FibromyalgiaCertaintyLowSourceTheoreticalnot used for recommendations1 other source
Expert guidance suggests that low-impact group activities, including Laughter Yoga, may support pain tolerance, mood and social function in people with Fibromyalgia.
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion
Why it isn't used for recommendations
No supporting study on file
Open FibromyalgiaShow studies (1)
Expert opinion50% confidenceLow-impact group interventions including Laughter Yoga improve pain tolerance, mood, and social function in fibromyalgia patients.
- →PMS (Premenstrual Syndrome)CertaintyLowSourceTheoreticalnot used for recommendations1 other source
Expert guidance suggests Laughter Yoga may improve mood and reduce perceived stress in women with PMS.
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion
Why it isn't used for recommendations
No supporting study on file
Open PMS (Premenstrual Syndrome)Show studies (1)
Expert opinion50% confidenceLaughter Yoga improves mood and reduces perceived stress in women with premenstrual syndrome, supporting its use as a non-pharmacological intervention.
Side effects
3 listedHighest probability
- →Fainting (Syncope)CertaintyLowSourceReference knowledge1 other source
A pharmacology reference notes that prolonged, forceful laughter can rarely trigger reflex fainting, particularly in susceptible individuals.
What the sources found
0 not observed · 0 unclear · 1 reportedconfidence 65/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Reference knowledge1
Open Fainting (Syncope)Show studies (1)
Reference knowledgenegative65% confidenceRarely, prolonged forceful laughter can trigger reflex syncope, particularly in susceptible individuals.
- →HyperventilationCertaintyLowSourceReference knowledge1 other source
A pharmacology reference notes that prolonged or intense laughter can cause respiratory alkalosis through excessive carbon dioxide expulsion, especially in people with anxiety or respiratory sensitivity.
What the sources found
0 not observed · 0 unclear · 1 reportedconfidence 55/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Reference knowledge1
Open HyperventilationShow studies (1)
Reference knowledgenegative55% confidenceProlonged or intense laughter can lead to respiratory alkalosis due to excessive CO2 expulsion, especially in individuals with anxiety or respiratory sensitivity.
- →DizzinessCertaintyLowSourceReference knowledge1 other source
A pharmacology reference notes that rapid shifts in blood pressure and blood flow to the brain during laughter may cause temporary dizziness, especially in older adults or people with autonomic dysfunction.
What the sources found
0 not observed · 0 unclear · 1 reportedconfidence 50/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Reference knowledge1
Open DizzinessShow studies (1)
Reference knowledgenegative50% confidenceRapid shifts in blood pressure and cerebral blood flow during laughter episodes may cause transient dizziness, especially in older adults or those with autonomic dysfunction.
Don't do it if
When to skip it or get medical advice first9 listedHighest probability
- →AnginaCertaintyLowSourceReference knowledgeTheoretical
Intense laughter may trigger sympathetic surges and hemodynamic stress, potentially precipitating ischemic events in people with active coronary instability.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 75/100
Open AnginaRationale
Episodes of intense laughter can trigger sympathetic surges and hemodynamic stress, potentially precipitating ischemic events in individuals with active coronary instability.
- →Recent Heart Attack (MI)CertaintyLowSourceReference knowledgeTheoretical
In the early post-infarction phase (within 4–6 weeks), vigorous laughter and physical movement may increase the heart’s oxygen demand and arrhythmia risk.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 75/100
Open Recent Heart Attack (MI)Rationale
Vigorous laughter and physical movement may increase myocardial oxygen demand and risk of arrhythmia in the early post-infarction phase (within 4–6 weeks).
- →Post-Surgery RecoveryCertaintyLowSourceReference knowledgeTheoretical
Vigorous diaphragm contractions and increased abdominal pressure during laughter can stress healing incisions, particularly after abdominal or thoracic surgery, increasing the risk of wound separation or pain.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 75/100
Open Post-Surgery RecoveryRationale
The vigorous diaphragmatic contractions and increased intra-abdominal pressure during laughter can stress healing surgical incisions, particularly abdominal or thoracic, increasing risk of dehiscence or pain.
- →Acute Febrile IllnessCertaintyLowSourceReference knowledgeTheoretical
During an active febrile illness, the exertion and increased respiratory demand of laughter yoga may worsen symptoms and delay recovery.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 70/100
Open Acute Febrile IllnessRationale
The physical exertion and increased respiratory demand of laughter yoga can exacerbate symptoms and delay recovery during an active febrile illness.
- →Recent StrokeCertaintyLowSourceReference knowledgeTheoretical
During early recovery (<6 weeks) after a hemorrhagic or large ischemic stroke, forced exhalation during laughter may raise cerebral pressure.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 70/100
Open Recent StrokeRationale
Increased intrathoracic pressure during forced exhalation in laughter may elevate cerebral pressure, posing risk in early recovery phase (<6 weeks) after hemorrhagic or large ischemic stroke.
- →Retinal DetachmentCertaintyLowSourceReference knowledgeTheoretical
Prolonged laughter may create Valsalva-like forces that raise intraocular pressure, posing a risk of retinal re-detachment in post-surgical or high-risk eyes.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 70/100
Open Retinal DetachmentRationale
Valsalva-like forces during prolonged laughter may increase intraocular pressure and risk of retinal re-detachment in post-surgical or high-risk eyes.
- →AsthmaCertaintyLowSourceReference knowledgeTheoretical
During an active asthma exacerbation, or when laughter is a known bronchospasm trigger, deliberately sustained laughter may worsen airway narrowing and breathing difficulty.
In the trials
1 trial of this practice also left out people with this condition. That does not show harm.
PubMed links (1)
Where the evidence comes from
- Reference knowledge
Confidence
confidence 68/100
Open AsthmaRationale
During an active exacerbation, or when laughter is a known bronchospasm trigger for the person, deliberately sustained laughter may worsen bronchoconstriction and breathing difficulty.
Low probability(2)
- →EpilepsyCertaintyLowSourceReference knowledgeTheoretical
In susceptible individuals, the emotional arousal and hyperventilation that can accompany intense laughter may lower the seizure threshold.
In the trials
5 trials of this practice also left out people with this condition. That does not show harm.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 65/100
Open EpilepsyRationale
Intense emotional arousal and hyperventilation during laughter may lower seizure threshold in susceptible individuals.
- →Herniated DiscCertaintyLowSourceReference knowledgeTheoretical
In the acute phase, sudden trunk movements and pressure spikes during laughter may worsen radicular pain or disc-related inflammation.
Where the evidence comes from
- Reference knowledge
Confidence
confidence 60/100
Open Herniated DiscRationale
Sudden trunk movements and intra-abdominal pressure spikes during laughter may exacerbate radicular pain or discogenic inflammation in acute phase.
Who the trials left out
Some trials of this practice did not take people with these conditions, so the studies say less about them. This is not a warning and does not show harm. Ask a clinician first.15 listed- Glaucomaleft out by 3 trials
PubMed links (3)
- Hypertension (High Blood Pressure)left out by 3 trials
PubMed links (3)
- Diabetes (General)left out by 2 trials
PubMed links (2)
Left out by one trial each (11)
- Alzheimer's Diseaseleft out by 1 trial
PubMed links (1)
PubMed links (1)
- Cancer (General)left out by 1 trial
PubMed links (1)
- COPD (Chronic Obstructive Pulmonary Disease)left out by 1 trial
PubMed links (1)
- Coronary Artery Diseaseleft out by 1 trial
PubMed links (1)
- Bone Fractureleft out by 1 trial
PubMed links (1)
- Heart Disease (General)left out by 1 trial
PubMed links (1)
- Multiple Sclerosisleft out by 1 trial
PubMed links (1)
- Strokeleft out by 1 trial
PubMed links (1)
- Thrombocytopenia (Low Platelets)left out by 1 trial
PubMed links (1)
- Urinary Incontinenceleft out by 1 trial
PubMed links (1)
When you stop
Rebound and withdrawal after discontinuing1 listedHighest probability
- →Mood SwingsCertaintyLowSourceTheoreticalloss of benefit1 other source
The mood-elevating effects of Laughter Yoga are activity-dependent: stopping can lead mood to gradually return to baseline, particularly when it was the person’s primary positive activity.
What the sources found
0 not observed · 0 unclear · 1 reportedconfidence 35/100
How big is the effect
No study gave a number we could compare, so the size is not known.
Where the evidence comes from
- Expert opinion1
Open Mood SwingsShow studies (1)
Expert opinionnegative35% confidenceThe mood-elevating effects of laughter yoga are activity-dependent; cessation leads to a gradual return to baseline mood levels, particularly if it was the primary positive activity in one's routine.
Interactions
Combine with caution
Highest severity first
- →Alcohol (Ethanol)TheoreticalCaution
Alcohol can impair coordination and increase the risk of falls during group movement. It may also lower inhibitions excessively, contributing to unsafe behavior or vocal strain.
- →Cannabis / THC / CBDTheoreticalCaution
Cannabis may impair judgment and increase the risk of overexertion or injury during vigorous laughter and movement. It may also worsen tachycardia or anxiety in susceptible individuals.
Where the evidence comes from
- Reference knowledge
Open Cannabis / THC / CBDConfidence
confidence 75/100
Okay to combine with
Highest probability of useful synergy
- →PracticesMeditationCertaintyMediumSourceReference knowledgeComplementary
Combining Meditation with Laughter Yoga may support emotional regulation and stress reduction through complementary parasympathetic and social-engagement systems.
- →PracticesBreathworkCertaintyMediumSourceReference knowledgePotentiating
Laughter Yoga includes deep diaphragmatic breathing, which may complement formal Breathwork practices in supporting respiratory function and vagal tone.
- →SupplementsAshwagandhaCertaintyMediumSourceReference knowledgeAdditive
Ashwagandha may support stress resilience and cortisol regulation, potentially complementing Laughter Yoga’s anxiolytic and mood-stabilizing effects.
- →PracticesGroup TherapyCertaintyMediumSourceTheoreticalComplementary
Laughter Yoga may serve as a warm-up or adjunct to Group Therapy by easing initial social anxiety, building group cohesion, and facilitating emotional openness.
Weakens or is weakened by
Highest probability
- →SupplementsCaffeineCertaintyMediumSourceReference knowledgeCompetitive
High caffeine intake may counteract Laughter Yoga’s calming and parasympathetic-promoting effects, potentially increasing baseline anxiety and reducing its perceived benefit.
How it works
The mechanisms this practice works through24 listed · 0 established- Beta-endorphin and cortisolPhysiological changesproposed
Laughter therapy may increase beta-endorphin levels and decrease cortisol, contributing to improved mood.
- CortisolStress responseproposed
Laughter yoga did not significantly change cortisol levels in children, possibly due to lower baseline stress.
- CortisolNeuroendocrineproposed
Simulated laughter reduces release of neuroendocrine and stress hormones, lowering serum cortisol levels.
- Dopamine and endorphinsNeurochemicalproposed
Laughter promotes release of dopamine and endorphins, enhancing pleasure and immune function.
- Dopamine and serotoninNeurotransmitter modulationproposed
Laughter boosts dopamine and serotonin activities, positively affecting anxiety and depression.
- Epinephrine, cortisol, 3,4-dihydrophenylacetic acidStress hormone suppressionproposed
Laughter suppresses bioactivities of epinephrine, cortisol, and 3,4-dihydrophenylacetic acid, reducing stress.
- HbA1cGlycemic controlproposed
Laughter yoga reduced HbA1c levels, possibly through mechanisms such as increased energy expenditure, stress reduction, and positive affect.
- Lung capacityRespiratoryproposed
Deep breathing expands the thorax, promotes gas exchange, and increases lung capacity.
- Natural Killer (NK) cell activityImmune functionproposed
Laughter lowers salivary Chromogranin A levels but elevates serum endorphin and serotonin levels, and boosts NK cell activity.
- Oxygen intakeRespiratoryproposed
Deep breathing exercises in laughter therapy may increase oxygen intake, potentially improving mental state.
- Pain threshold and toleranceEndorphin releaseproposed
Laughter yoga boosts endorphin hormone release, raising pain threshold and pain tolerance.
- Parasympathetic activationAutonomic nervous systemproposed
Deep breathing in yoga activates the parasympathetic system and reduces sympathetic activity.
- Positive affectPsychological well-beingproposed
Laughter yoga increased positive affect scores, which may enhance adherence to health behaviors.
- Salivary IgAImmune functionproposed
Laughter yoga increased salivary IgA levels in children, suggesting enhanced mucosal immunity.
- Salivary cortisolNeuroendocrineproposed
Laughter yoga reduces salivary cortisol levels, indicating a reduction in physiological stress response.
- Sleep durationSleepproposed
Laughter yoga showed a trend toward increased sleep duration, which may be associated with better glycemic control.
- cortisol reductionendocrineproposed
Laughter may decrease cortisol, a stress hormone, potentially reducing stress-related symptoms.
- cortisol, endorphins, dopamineNeuroendocrine and autonomic regulationproposed
Authors propose laughter reduces cortisol and upregulates endorphins and dopamine; not measured in this meta-analysis.
- cytokine productionimmuneproposed
Laughter may affect cytokine production, modulating inflammation.
- depressionpsychologicalproposed
Laughter stimulates serotonin secretion and reduces cortisol production, alleviating depressive symptoms.
- endorphins and dopamine releaseneurologicalproposed
Laughter triggers release of endorphins and dopamine, which may enhance mood and pain tolerance.
- energy expenditureaerobic exerciseproposed
Laughter yoga involves light exercise and laughter, estimated at 2-3 METs, potentially increasing energy expenditure.
- hypothalamic-pituitary-adrenal axisstress reductionproposed
Laughter may reduce stress and sympathetic nervous system activity, potentially reducing stress-induced overeating and leading to weight loss.
- pulmonary functionrespiratoryproposed
Laughter and breathing exercises improve FEV1 by enhancing ventilation and reducing residual volume.
Variations
4 documentedTypical protocol
26 protocolsEstimatedAcross every study of this practice, whatever the variation.
40 min · 2×/week
- Course
- 6 weeks
- Per week
- 88 min
- Rounds
- 1–8
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
74% of the corpus contributed
Classic Group Laughter Yoga
Beginner9/1040–43 min · 2 times a week
Classic Group Laughter Yoga
Beginner9/1040–43 min · 2 times a week40–43 min · 2 times a week
Editorial- How often
- 2 times a week
- Intensity
- Low
- Time of day
- Any time
- Where
- Indoors or outdoors
- Research depth
- Moderate
This version combines simulated laughter with yogic breathing, playful interaction, and a relaxation period at the end. Its face-to-face group format uses clapping and eye contact as part of the shared exercises.
No equipment needed.
As studied
6 protocolsEstimatedThe protocol the studies of this variation actually used.
40–43 min
- Course
- 5 weeks
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
Derived from3581052539415513395556423979934541485062+1 more in Sources
How it's done7 steps · 3 cues · 3 common mistakes
A general description of the practice, not instruction or medical advice.
Steps
- Begin with rhythmic hand clapping and gentle body warm-up movements for 5-10 minutes to energize the group.
- Practice deep yogic breathing: inhale deeply through the nose, filling the belly, and exhale fully through the mouth.
- Engage in childlike playfulness and eye contact with other participants to foster a sense of connection.
- Initiate simulated laughter exercises, such as 'greeting laughter' or 'milkshake laughter,' sustaining each laugh for 30-45 seconds.
- Alternate between specific laughter exercises and deep breathing breaks to maintain energy and oxygen flow.
- Conclude with guided laughter meditation, allowing spontaneous laughter to arise and then settle into silence.
- Finish with a grounding relaxation exercise, lying down or sitting comfortably with eyes closed for 5-10 minutes.
Cues
- · Maintain eye contact with others to make the laughter contagious.
- · Fake it until you make it—simulated laughter often turns into real laughter.
- · Keep your shoulders relaxed and jaw loose during laughter exercises.
Common mistakes
- Forcing the laughter from the throat instead of the diaphragm.
- Holding your breath between laughter bursts instead of breathing deeply.
- Standing rigidly; allow your body to move freely and playfully.
Studied protocols7 on file
- 40 min· 2×/week· 4 weeks· n=101· A repeated coursePMID 35810525
- 40 min· 1×/week· 5 weeks· n=83· A repeated coursePMID 39415513
- 43 min· 2×/week· 4 weeks· n=90· A repeated coursePMID 39799345
- 40 min· 2×/week· 8 weeks· n=64· A repeated coursePMID 41497087
- 40 min· 1.5×/week· 5 weeks· n=305· A repeated coursePMID 41485062
- 2×/week· 6 weeks· n=60· A repeated coursePMID 39555642
Online Virtual Laughter Yoga
Beginner8/1040–60 min · 2 times a week
Online Virtual Laughter Yoga
Beginner8/1040–60 min · 2 times a week40–60 min · 2 times a week
From studies- How often*
- 2 times a week
- Intensity
- Low
- Time of day
- Any time
- Where
- Indoors
- Research depth
- Minimal
A facilitator leads this version over video, adapting group laughter exercises for participants joining from home. It uses camera-visible expressions and shared vocal laughter, followed by guided relaxation.
Equipment: Computer or smartphone with camera, Stable internet connection
As studied
3 protocolsMeasuredThe protocol the studies of this variation actually used.
60 min · 2×/week
- Course
- 4 weeks
- Per week
- 120 min
- Format
- Group
A repeated course
How it's done7 steps · 3 cues · 3 common mistakes
A general description of the practice, not instruction or medical advice.
Steps
- Set up your device at eye level in a quiet, well-lit room where you can move your arms freely.
- Join the virtual session and greet other participants with waves and smiles to build social presence.
- Follow the facilitator's lead for warm-up clapping and deep breathing, ensuring you are visible on camera.
- Perform simulated laughter exercises like 'cell phone laughter' or 'credit card laughter,' exaggerating facial expressions for the screen.
- Engage in playful, childlike games adapted for solo participation, such as miming actions.
- Participate in group laughter by unmuting to share vocal laughter, then muting again for breathing exercises.
- Conclude with a guided relaxation, closing your eyes and focusing on the facilitator's voice for a grounding meditation.
Cues
- · Look directly into the camera to simulate eye contact with others.
- · Use headphones to minimize audio feedback and stay immersed.
- · Let your body sway and move naturally, even in a seated position.
Common mistakes
- Multitasking or checking emails during the session, which reduces engagement.
- Sitting too far from the camera so your expressions are lost.
- Staying muted the entire time, missing the benefit of shared vocal laughter.
Studied protocols4 on file
- 60 min· 2×/week· 5 weeks· n=80· A repeated coursePMID 35782290
- 2×/week· 4 weeks· n=61· A repeated coursePMID 36428060
- 2×/week· 4 weeks· n=90· A repeated coursePMID 37023316
- 9 weeks· n=1344· A repeated coursePMID 42001147
Clinical Short-Form Laughter Yoga
Beginner7/10supervision recommended25–30 min · Weekly
Clinical Short-Form Laughter Yoga
Beginner7/10supervision recommended25–30 min · Weekly25–30 min · Weekly
Editorial- How often
- Weekly
- Intensity
- Very low
- Time of day
- First half of the day
- Where
- Indoors
- Research depth
- Minimal
This 25-minute format uses 15 structured laughter steps with breathing breaks and gentle, seated warm-ups. It is designed for small groups of patients, including in clinical settings such as before chemotherapy or during dialysis.
No equipment needed.
As studied
4 protocolsMeasuredThe protocol the studies of this variation actually used.
25–30 min
- Course
- 4 weeks
- Intensity
- Low
- Format
- Group
- Supervision
- Instructor-led
A repeated course
How it's done7 steps · 3 cues · 3 common mistakes
A general description of the practice, not instruction or medical advice.
Steps
- Sit comfortably in a chair or hospital bed, with a small group of 8-14 patients arranged in a circle.
- Begin with gentle, seated warm-ups: slow neck rolls, shoulder shrugs, and ankle circles.
- Practice deep diaphragmatic breathing: inhale for 4 counts, hold for 2, and exhale for 6 counts.
- Perform the first laughter exercise, such as 'greeting laughter,' sustaining the simulated laugh for 30-45 seconds.
- Cycle through the remaining 14 structured laughter steps, each followed by a deep breathing break.
- Maintain a playful, non-judgmental atmosphere, with the facilitator making eye contact and encouraging smiles.
- Conclude with a guided body scan relaxation, focusing on releasing tension from each muscle group.
Cues
- · Focus on the rhythmic pattern of the laugh rather than the sound.
- · If you feel tired, simply smile and breathe deeply until the next exercise.
- · Use gentle, contained movements to avoid interfering with any medical lines.
Common mistakes
- Overexerting physically; this is a low-intensity, restorative practice.
- Comparing your laughter to others; any level of participation is beneficial.
- Skipping the breathing breaks, which are essential for maintaining comfort.
Studied protocols4 on file
- 30 min· 3×/week· 4 weeks· n=17· A repeated coursePMID 26055513
- 25 min· 1×/week· 4 weeks· n=69· A repeated coursePMID 37303065
- 25 min· 1×/week· 4 weeks· n=69· A repeated coursePMID 38222968
- 25 min· n=315PMID 38803758
Extended Wellness Laughter Yoga
Intermediate7/1060–90 min · Weekly
Extended Wellness Laughter Yoga
Intermediate7/1060–90 min · Weekly60–90 min · Weekly
Editorial- How often
- Weekly
- Intensity
- Low
- Time of day
- Morning
- Where
- Indoors
- Research depth
- Minimal
The 90-minute session includes a 30-minute educational component followed by 60 minutes of practice. The practice builds from warm-ups and breathing into laughter exercises, a 15-minute laughter meditation, and a 15-minute guided relaxation.
No equipment needed.
How it's done7 steps · 3 cues · 3 common mistakes
A general description of the practice, not instruction or medical advice.
Steps
- Attend the 30-minute educational component, which covers the science of laughter and its physiological benefits.
- Transition to the physical practice with 10 minutes of dynamic warm-ups, including stretching, clapping, and chanting.
- Engage in deep yogic breathing exercises, such as alternate nostril breathing, to center the mind.
- Perform a progressive series of laughter exercises, starting with gentle chuckles and building to full belly laughs.
- Incorporate playful, childlike games that encourage spontaneous movement and interaction with others.
- Move into a 15-minute laughter meditation, allowing laughter to flow freely without forced effort.
- Conclude with a 15-minute guided deep relaxation, lying in savasana with a focus on the breath.
Cues
- · Pace yourself; the extended format allows time to explore each exercise deeply.
- · Let go of self-consciousness during the playful games—the goal is childlike freedom.
- · Use the educational insights to mentally reinforce the health benefits as you practice.
Common mistakes
- Treating the lecture and practice as separate; integrate the knowledge into your movements.
- Rushing through the warm-up, which is crucial for preventing strain in a longer session.
- Forcing laughter during meditation; simply observe and allow any impulses to arise naturally.
Studied protocols2 on file
- 90 min· 1×/week· 12 weeks· n=42· A repeated coursePMID 37065750
- 90 min· 12 weeks· n=235· A repeated coursePMID 35461239
How to start
Community experience
Based on 68 public posts from Reddit, Bluesky, YouTube, and Hacker News.
What people report it did
4 outcomes mentioned across 68 public reports. A report often mentions several, so these counts do not add up to the total.
Reported benefits2
- Mood Improvement33 mentions
- Anxiety Reduction5 mentionspointed the other way
Reported side effects2
- Muscle Ache (Myalgia)not studied
- Muscle Strainnot studied
What people report doing
Counted from public posts and videos, not from a survey. Each figure counts the posts that mentioned it — most reports say nothing about schedule.
How often7 mentions
Where8 mentions
When2 mentions
Session lengthas written
How long they've practisedas written
References
35 screened · 35 analysed · 36 listed below
Studies and sources cited on this page. Evidence quality varies — check the grade on each.
- Effects of laughter therapy on depression and anxiety: A dose-response meta-analysis with trial sequential analysis.J Psychiatr Res2026Meta-analysisA
- Effects of laughter therapy on improving physical and psychological symptoms among cancer patients: a systematic review and meta-analysis.Support Care Cancer2025Meta-analysisA
- Laughter intervention for stress reduction in adults: a systematic review and meta-analysis of randomized controlled trials.BMC Psychol2026Meta-analysisBn=1344
- Effects of laughter therapy in patients with cancer: A systematic review of randomized clinical trials.Complement Ther Med2026Systematic reviewBn=1127
- The effect of laughter therapy on self-efficacy and psychological well-being in nursing students.Arch Psychiatr Nurs2024RCTBn=208
- Effects of Laughter Therapy on Improving Negative Emotions Associated with Cancer: A Systematic Review and Meta-Analysis.Oncology2024Meta-analysisB
- The Efficacy of Laughter Therapy on Psychological Symptoms in People With Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Studies.Psychooncology2024Meta-analysisBn=543
- Effects of a laughter program on body weight and mental health among Japanese people with metabolic syndrome risk factors: a randomized controlled trial.BMC Geriatr2022RCTBn=235
- The Effect of Laughter Therapy on Anxiety: A Meta-analysis.Holist Nurs Pract2020Meta-analysisBn=157
- The effect of laughter yoga on mental health, emotional, and cognitive functions of children: A systematic review.Acta Psychol (Amst)2026Systematic reviewC
Show all 36 references
- The effect of 8 weeks of laughter yoga training on cardiorespiratory indices in adolescent girls aged 13-15 in Shahrekord.2026Quasi ExperimentalCn=64
- Healing with laughter: the therapeutic power of laughter yoga in pediatric health - a systematic review.2026Systematic reviewCn=305
- The effect of laughter yoga on well-being, perceived stress, and academic self-efficacy in nursing students: A randomized controlled trial.2025RCTCn=83
- Investigating the effect of laughter yoga on happiness and life expectancy in an elderly population.2025RCTCn=220
- The Effect of Laughter Yoga on Chemotherapy-Induced Symptoms and Sleep Quality in Patients with Haematologic Cancer.2025RCTCn=60
- Effects of laughter yoga practiced by the first year nursing students before clinical practice on their perceptions of stress and meaning of life: a randomized controlled trial.2025RCTCn=90
- The effect of laughter yoga and music intervention on depression, anxiety, and stress in the Rafsanjan-Iran aged: a randomized clinical trial study.2025RCTCn=91
- Effect of laughter yoga on anxiety and depression in people with Parkinson's disease: a randomized controlled trial.2025RCTCn=94
- Effects of Laughter Yoga on Patients Receiving Hemodialysis: A Systematic Review.2024Systematic reviewC
- A structured laughter yoga therapy program on patients with chemotherapy-induced nausea and vomiting: A randomized clinical trial.2024RCTCn=69
- Efficacy and Safety of Laughter Yoga in Cancer Patients: A Scoping Review of Randomized Controlled Trials.2024Systematic reviewCn=315
- The impact of laughter yoga as a NIC on health parameters in nurses and nursing students: a systematic review.2024Systematic reviewCn=617
- Effect of Laughter Yoga on School Burnout and Hope Among Secondary School (Eighth Grade) Students: A Parallel Group Randomized Control Trial.2024RCTCn=60
- The Effect of Laughter Yoga on the Psychological Resilience and Sleep Quality of Nurses During the Pandemic: A Randomized Controlled Trial.2023RCTCn=90
- Effects of laughter yoga on health-related quality of life in cancer patients undergoing chemotherapy: a randomized clinical trial.2023RCTCn=69
- Laughter yoga as an enjoyable therapeutic approach for glycemic control in individuals with type 2 diabetes: A randomized controlled trial.2023RCTCn=42
- The Effects of Laughter Yoga on Perceived Stress, Positive Psychological Capital, and Exercise Capacity in Lung Cancer Chemotherapy Patients: A Pilot Randomized Trial.2023RCTCn=80
- The effect of laughter therapy on nursing students' anxiety, satisfaction with life, and psychological well-being during the COVID-19 pandemic: Randomized controlled study.2022RCTCn=80
- Effects of Simulated Laughter Therapy Using a Breathing Exercise: A Study on Hospitalized Pulmonary Tuberculosis Patients.2022Quasi ExperimentalCn=52
- The effect of online laughter therapy on depression, anxiety, stress, and loneliness among nursing students during the Covid-19 pandemic.2022RCTCn=61
- The effect of laughter yoga on perceived stress, burnout, and life satisfaction in nurses during the pandemic: A randomized controlled trial.2022RCTCn=101
- A systematic review of the effect of laughter yoga on physical function and psychosocial outcomes in older adults.2020Systematic reviewC
- Effects of laughter therapy on quality of life in patients with cancer: An open-label, randomized controlled trial.2019RCTCn=56
- The effects of group-based Laughter Yoga interventions on mental health in adults: A systematic review.2018Systematic reviewC
- Intradialytic Laughter Yoga therapy for haemodialysis patients: a pre-post intervention feasibility study.2015Quasi ExperimentalDn=17
- Expert knowledge synthesis