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substance

Cannabis / THC / CBD

Considering Cannabis / THC / CBD with another medication? Explore interaction questions involving Marijuana, Marinol (dronabinol), and CBD products.

Interactions

Supplement interactions on file

No supplement in this library is recorded as interacting with this medication. Coverage is partial — 171 of 216 medications have interaction data, drawn from the 107 supplements written up so far. Absence here is incomplete coverage, not a safety claim.

Browse the supplements that are written up

Trade names
Marijuana, Marinol (dronabinol), CBD products

Full write-up

What is it

Cannabis / THC / CBD is classified as a substance. It may be encountered under the names Marijuana, Marinol (dronabinol), and CBD products. This page provides educational reference information about potential interaction questions involving these products and other medications. It is not medical advice or a guide to starting or stopping treatment; anyone considering these questions in the context of a medical condition can consult a clinician.

What interacts with it

The most important cautions involve additive effects. Caffeine may intensify cannabis-related tachycardia and anxiety, increasing the possibility of panic attacks and palpitations. Products containing THC or sedating cannabinoids may also add to the drowsiness, dizziness, and impaired coordination associated with Lavender Extract or Lemon Balm (Melissa).

Melatonin and Valerian Root can likewise add to cannabis-related sedation and psychomotor impairment. With Melatonin, this may increase the risk of falls, driving impairment, and accidents. With Valerian Root, combined use may also worsen dizziness and cognitive impairment. Both may have anxiolytic and sleep-promoting effects through complementary mechanisms, but the potential synergy means this combination requires strict medical supervision.

CBD (Cannabidiol) and THC can interact, with effects varying according to dose, THC:CBD ratio, formulation, route, and individual susceptibility. CBD does not reliably prevent THC-induced anxiety, psychotic symptoms, sedation, or impairment. Because several of these combinations can affect alertness, coordination, anxiety, or cardiovascular symptoms, discuss their use with a prescriber or pharmacist, particularly when combining more than one sedating product or when driving and other activities requiring full alertness are involved.

Diatelos provides general wellness information based on published research. It is not medical advice. Talk to a clinician before starting any new supplement or practice, especially if you have a health condition, are pregnant, or take medication.