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Breathwork

Alternate Nostril Breathing (Nadi Shodhana)

Alternate Nostril Breathing (Nadi Shodhana) is a breathwork practice centered on alternating nostril breathing. Research has explored possible effects on cardiovascular and autonomic measures, breathing patterns, and cognitive function, rather than establishing it as a treatment for a specific condition.

Alternate Nostril Breathing is a breathwork practice that alternates between the nostrils.

Part of Breathwork

Overview

Alternate Nostril Breathing (Nadi Shodhana) is a breathwork practice centered on alternating nostril breathing. Research has explored possible effects on cardiovascular and autonomic measures, breathing patterns, and cognitive function, rather than establishing it as a treatment for a specific condition. The overall picture is not settled: research spans several areas and includes review-level analysis, but most findings do not rest on the strongest evidence. Firm conclusions about benefits therefore remain limited.

Some research: 52 studies. Last checked Oct 9, 2026.

25
human evidence
6
eligible
2
unclassified
2
animal / null result

Best-evidenced uses

2 of 3 flagged interactions are serious or life-threatening·5 variations documented

EvidenceModerate
52
Studies

Evidence checked Oct 9, 2026 · newest study 2026

The text on this page was written before the latest evidence check. The tables and numbers are up to date.

Study designs:Meta-analysis2Systematic review1RCT29Quasi Experimental16Cross Sectional2Pilot study1Qualitative1
Study grades:
B
2
C
49
D
1

291 community reports across 4 platforms

Coverage

Effects
27
Helps with
8
Side effects
3
Interactions
21
2 high-risk
How to read the evidence

Evidence tier — overall strength of the evidence for the whole compound

  • StrongWell established — backed by strong, consistent human research.
  • ModerateSome genuine support, but mostly from small or lower-quality studies. Promising, not proven.
  • PreliminaryEarly-stage evidence — a promising hypothesis, not an established effect yet.
  • LimitedVery limited evidence — treat this as a hypothesis, not proof.
  • InsufficientNot enough good evidence to draw conclusions yet.

Certainty — how sure we can be that the effect is real

  • Very highVery sure — strong, consistent evidence
  • HighFairly sure — consistent evidence from good studies
  • MediumModerately sure — new studies could change this
  • LowNot sure — little or mixed evidence
  • Very lowVery unsure — almost no usable evidence

Source — where the data comes from

  • Meta-analysisPooled analysis of many trials — the strongest evidence
  • RCTRandomized controlled trial — a strong human study design
  • ClinicalA human clinical study
  • Reference knowledgeFrom general health-science or pharmacology references, not a study of this exact claim
  • Animal researchStudied in animals, not humans
  • Community reportsAggregated user reports — anecdotal signal, not evidence
  • TheoreticalMechanism-based reasoning, not yet tested

Study grade — quality of each underlying study (A best, D weakest)

  • AHigh-quality — strong, consistent human trials
  • BGood — solid evidence with some limitations
  • CModerate — limited, small, or mixed-quality studies
  • DWeak — preliminary, indirect, or animal-only

Confidence — how strongly the sources back a finding

A 0–100 score from study quality and agreement

Most supplement evidence is graded C–D. Read it as preliminary signal, not proof.

Interacts with some medications and supplements — worth checking before combining.See interactions

These are research findings, not promises. A practice does not replace medical treatment.

What does research say?

What studies found for each claimed effect, best evidence first.

27 claims:9 some evidence1 mixed15 not enough evidence1 personal stories only1 no benefit found

  • Blood Pressure SupportBreathwork in general: Medium · 11 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 17 studies with a clear result found a benefit. Strongest study: a pooled analysis of several trials. A trial found it after a single session. Trials that found it ran as little as 0.7 weeks, typically 4.

    Open the Blood Pressure Support pageCompare with Breathwork in general →
  • Resting Heart Rate ImprovementBreathwork in general: Medium · 3 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 7 studies with a clear result found a benefit. Strongest study: a randomized controlled trial. Trials that found it ran as little as 0.7 weeks, typically 4.

    Open the Resting Heart Rate Improvement pageCompare with Breathwork in general →
  • Anxiety ReductionBreathwork in general: Medium · 23 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    7 of 9 studies found a benefit; 2 found none. Strongest study: a randomized controlled trial. Trials that found it typically ran 4 weeks.

    Findings are mixed: a 2013 randomized trial of 96 participants reported improved anxiety scores, while a 2025 randomized trial of 68 found a non-significant decrease in anxiety scores after follow-up, both within the test group and compared with the control group.

    Open the Anxiety Reduction pageCompare with Breathwork in general →
  • Cognitive Function ImprovementBreathwork in general: Medium · 4 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 4 studies with a clear result found a benefit. Strongest study: a randomized controlled trial. A trial found it after a single session.

    A 2019 randomized trial of 50 participants found that errors on a shape and size discrimination task fell by -33.1% after an Alternate Nostril Breathing session. A 2025 randomized trial also reported improved cognition in the test group.

    Open the Cognitive Function Improvement pageCompare with Breathwork in general →
  • Reaction Speed IncreaseBreathwork in general: Medium · 3 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 3 studies with a clear result found a benefit. Strongest study: a randomized controlled trial. A trial found it after a single session.

    Open the Reaction Speed Increase pageCompare with Breathwork in general →
  • Cardiovascular Health SupportBreathwork in general: Medium · 5 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    4 of 5 studies found a benefit; 1 found none. Strongest study: a randomized controlled trial.

    A 2024 randomized trial of 100 participants reported reductions in heart rate, systolic and diastolic blood pressure, mean arterial pressure, and rate pressure product after the intervention.

    Open the Cardiovascular Health Support pageCompare with Breathwork in general →
  • Stress Resilience ImprovementBreathwork in general: Medium · 12 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 4 studies with a clear result found a benefit. Strongest study: a randomized controlled trial. A trial found it after a single session. Trials that found it ran as little as 8 weeks, typically 10.

    A 2025 randomized trial of 86 people with Parkinson's disease reported decreases in depression, anxiety, stress, and negative affect in the test group compared with the control group. A separate 2024 trial assessed psychological stress and concluded that its breathing module may help curtail stress and improve well-being.

    Open the Stress Resilience Improvement pageCompare with Breathwork in general →
  • Mood ImprovementBreathwork in general: Medium · 16 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 2 studies with a clear result found a benefit. Strongest study: a randomized controlled trial.

    A 2025 randomized trial reported improved positive affect after 12 weeks in people with Parkinson's disease in the test group compared with the control group.

    Open the Mood Improvement pageCompare with Breathwork in general →

Only reported by users, not studied: Present Moment Awareness, Biorhythm Regulation, Emotional Regulation Improvement, Physical Energy Increase, Sleep Onset Improvement, and Interoception Improvement.

What to expect

Some findings, including changes in blood pressure, heart rate variability, and cognitive function, were reported after a single session. Across trials, blood pressure and resting heart rate findings were also measured at the end of programmes lasting 0.7 to 4 weeks; anxiety findings were measured after 4 weeks. Heart rate variability and stress-resilience findings were measured after programmes lasting 6–9 weeks and 8–10 weeks, respectively. These are trial timelines, not guaranteed onset times.

Also studied in people with 8 health conditions

How strong the evidence is in each group. This is research, not a treatment recommendation.

  • Hypertension (High Blood Pressure)Breathwork in general: Medium · 8 trialsSome evidence it helpsSize of effect: Not known

    Some human studies found a benefit. More research could change this.

    All 9 studies with a clear result found a benefit.

    A meta-analysis of 15 randomized trials found that breathing exercises reduced SBP by −7.06 mmHg and DBP by −3.43 mmHg in hypertensive adults. A systematic review of 15 studies found improvements in blood pressure, lipid profiles, and inflammatory markers among hypertensive patients practicing yoga.

    Open the Hypertension (High Blood Pressure) pageCompare with Breathwork in general →
  • GlaucomaBreathwork in general: 1 trialNot enough evidence

    Too few or too small studies to know if it works.

    1 of 2 studies found a benefit; 1 found none.

    A trial in 60 people with glaucoma found that the Alternate Nostril Breathing exercise group had improved IOP and glaucoma-related quality of life.

    Open the Glaucoma pageCompare with Breathwork in general →
  • Kidney Disease (General)Not enough evidence

    Too few or too small studies to know if it works.

    The one study found a benefit.

    A randomized controlled trial involving 69 patients undergoing hemodialysis reported that breathing exercises reduced pain and improved sleep and symptoms in this group.

    Open the Kidney Disease (General) page
  • MigraineBreathwork in general: 1 trialNot enough evidence

    Too few or too small studies to know if it works.

    The one study found a benefit.

    An RCT in 86 people with migraine found that Alternate Nostril Breathing reduced migraine frequency and MIDAS scores compared with usual care.

    Open the Migraine pageCompare with Breathwork in general →
  • Parkinson's DiseaseBreathwork in general: 2 trialsNot enough evidence

    Too few or too small studies to know if it works.

    The one study found a benefit.

    A randomized controlled trial involving 86 people with Parkinson's disease found improvements in cardiac autonomic balance, cognition, psychological status, and quality of life when the practice was used as an adjunctive therapy.

    Open the Parkinson's Disease pageCompare with Breathwork in general →
  • Pleural EffusionNot enough evidence

    Too few or too small studies to know if it works.

    The one study found a benefit.

    A quasi-experimental study examined alternate nostril breathing after fluid aspiration in 10 patients with pleural effusion, using lung re-expansion as the measured outcome.

    Open the Pleural Effusion page
  • InsomniaNot tested in people

    Only tested in animals, cells or theory. Results like these often do not carry over to people.

    The one study found a benefit.

    Integrative protocols recommend the practice as a non-pharmacological approach to insomnia, with the rationale that it promotes parasympathetic activation and reduces pre-sleep arousal.

    Open the Insomnia page
  • Myopia ProgressionNo benefit found

    Studies looked for a benefit and did not find one.

    The one study found no benefit.

    A randomized controlled trial involving 60 people found that 3 months of yoga therapy did not reduce changes in visual acuity or clinical refraction; only associated symptoms improved.

    Open the Myopia Progression page

Studied only as breathwork in general, not tested in alternate nostril breathing (nadi shodhana) yet

These results come from studies of breathwork as a whole. No study of alternate nostril breathing (nadi shodhana) has looked at them yet.

COPD (Chronic Obstructive Pulmonary Disease) (Medium · 19 trials) · Physical Endurance Increase (Medium · 14 trials) · Fatigue Reduction (Medium · 8 trials) · Lung Cancer (High · 8 trials) · Anxiety Disorder (General) (Medium · 7 trials) · Oxygen Utilization Improvement (Medium · 6 trials) · and 13 more

All outcomes on the Breathwork page →

Before you try it

What studies and reports say about side effects and who it may not suit.

Side effects

With weak evidence: Fainting (Syncope), Dizziness, and Hyperventilation.

May not suit you if you have
Hypotension (Low Blood Pressure), Recent Stroke, and Pheochromocytoma
Some trials left out people with
Hypertension (High Blood Pressure), Asthma, Heart Disease (General), Obesity, and 1 more
Serious interactions with
Decongestants and Yohimbine
Reported by users
Anxiety Increase (6 posts), Insomnia, Paresthesia (Tingling/Numbness), Rhinitis (Runny Nose), and 1 more
Also listed for breathwork in general (written by our reviewers)
Aortic Aneurysm · Epilepsy · Bipolar Mania · Psychosis · Unstable Heart Disease (Unstable Angina / Decompensated Heart Failure)Precautions from the Breathwork page. They are for breathwork as a whole and may not all fit alternate nostril breathing (nadi shodhana).

General wellness information, not medical advice. Ask a doctor before you start, especially if you take medicines or have a health condition.

How people do it

A gentle start, then what the studies used.

Start with
5 minutes, every other day (Basic Alternate Nostril Breathing)A gentle start based on the easiest variation, not on a study.
Build up to
15 minutes, 7 times a week, low intensity (what the studies used)
What the studies ran
105 minutes a week for 5 weeks

The expert view shows every study, dose protocol and source.

Effects

27 listed

Start here

Most likely to help, from the evidence we have

  1. Blood Pressure SupportCertaintyMediumSourceRCTlong-term16 cited studies · 1 other source

    A 2024 meta-analysis of randomized trials, covering 525 people in its systolic blood pressure analysis, found that Alternate Nostril Breathing lowered systolic blood pressure by MD -7.16 mmHg [-7.86, -6.45] compared with no intervention or placebo.

    What the sources found

    17 positive · 0 neutral · 0 negativeconfidence 57/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from High to Medium after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people and patients
    • Diabetes Type2
    • Glaucoma
    • Hypertension (High Blood Pressure)
    • Hypothyroidism
    • Shift Work Disorder

    Where the evidence comes from

    • Article16
    • Expert opinion1

    Protocol behind this outcome

    11 protocolsEstimated

    What the studies reporting this result did.

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Courses and single sessions · 4 repeated-course and 7 single-session protocols

    What worked in trials9 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session10 min12 min
    How often7×/week
    Per week70 min105 min
    Derived from (9)

    2333406331463330325431623421347137290219+4 more in Sources

    Timing

    A trial found it after a single session

    Trials that found it ran as little as 0.7 weeks, typically 4

    Show studies (17)
    Meta-analysisBpositiven=137755% confidence2024

    Effectiveness of Alternative Nostril Breathing on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    ANB was better in reducing SBP than that of the control group (nonintervention or placebo) (mean difference [MD]: -7.16, 95% confidence interval [CI]: -7.86 to -6.45, I2: 93%).

    MD -7.16 [-7.86, -6.45]Weak journalPooled RCTsStudies disagree (I² 93%)Main outcomeOpen-labelSham comparison
    RCTCpositiven=17075% confidence2019

    Effect of alternate nostril breathing exercise on blood pressure, heart rate, and rate pressure product among patients with hypertension in JIPMER, Puducherry.

    There was a marked reduction in the systolic BP after the continuous 5-days alternate nostril breathing exercise in the study group. P < 0.0001 indicated that the difference in systolic BP pre- and post-assessment on the 1st day and 5th day was statistically significant.

    MD -46.22Large effectMain outcomeOpen-labelInactive control
    RCTCpositiven=13260% confidence2024

    Immediate Hemodynamic Changes during Slow Uninostril and Alternate Nostril Breathing Patterns in Normotensive Adults.

    SBP decreased with very high statistical significance in ANB when compared to the SAV group [Figure 1]

    MD -12.2 [-21, -3.35]Large effectWeak journalMain outcomeOpen-label
    RCTCpositiven=10060% confidence2023

    Effects of Nadishodhana and Bhramari Pranayama on heart rate variability, auditory reaction time, and blood pressure: A randomized clinical trial in hypertensive patients.

    There was a significant decrease in SBP (p = 0.01) and DBP (p = 0.02).

    MD -2.8Small effectMain outcomeOpen-labelAllocation not hiddenCompleters onlyBorderline p-value
    RCTCpositiven=10055% confidence2024

    Effects of an 8-week intervention of anulom vilom pranayama combined with heartfulness meditation on psychological stress, autonomic function, inflammatory biomarkers, and oxidative stress in healthcare workers during COVID-19 pandemic: a randomized controlled trial.

    AVPHFN intervention resulted in a significant reduction in cardiovascular parameters heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure and rate pressure product (p

    Open-labelInactive control
    RCTCpositiven=10055% confidence2020

    Effects of alternate nostril breathing exercise on cardiac functions in healthy young adults leading a stressful lifestyle.

    The mean value pulse and BP were significantly (p < 0.001) changed after breathing exercise, compared to the values before the breathing exercise.

    Main outcomeNo control group
    +11 more in Sources
    Open Blood Pressure Support
    →

    Breathwork in general: Medium · 11 trials →

  2. Resting Heart Rate ImprovementCertaintyMediumSourceClinical7 cited studies · 1 other source

    An RCT of 170 participants found a mean heart-rate change of MD -1.37 bpm after breathing practice. A separate RCT also reported changes in pulse and blood pressure, but did not give their size here.

    What the sources found

    8 positive · 0 neutral · 0 negativeconfidence 53/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people and patients
    • Diabetes Type2
    • Hypertension (High Blood Pressure)
    • Hypothyroidism

    Where the evidence comes from

    • Article7
    • Community reports1

    Protocol behind this outcome

    2 protocolsMeasured

    What the studies reporting this result did.

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Single sessions · 0 repeated-course and 2 single-session protocols

    What worked in trials3 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session10 min
    How often7×/week10.5×/week
    Per week70 min105 min
    Derived from (3)

    314633303254316234213471

    Timing

    Trials that found it ran as little as 0.7 weeks, typically 4

    Show studies (8)
    RCTCpositiven=17075% confidence2019

    Effect of alternate nostril breathing exercise on blood pressure, heart rate, and rate pressure product among patients with hypertension in JIPMER, Puducherry.

    P < 0.0001 indicated that the difference in heart rate pre- and post–assessment on the 1st day and 5th day was statistically significant.

    MD -1.37Main outcomeOpen-labelInactive control
    RCTCpositiven=10055% confidence2020

    Effects of alternate nostril breathing exercise on cardiac functions in healthy young adults leading a stressful lifestyle.

    The mean value pulse and BP were significantly (p < 0.001) changed after breathing exercise, compared to the values before the breathing exercise.

    Main outcomeNo control group
    RCTCpositiven=10060% confidence2021

    Effects of alternate nostril breathing exercise on cardiorespiratory functions in healthy young adults.

    Pulse (beat/min): males 79.1 to 74.0 (P<0.001), females 78.8 to 71.5 (P<0.001) in experimental group

    Weak journalMain outcomeOpen-labelNo control group
    Cross SectionalCpositiven=28060% confidence2021

    Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers.

    HR (beats/ min) 80.11±11.63 to 77.66±7.76, P=0.001 (Group I); 83.46±9.70 to 78.31±8.29, P=0.000 (Group II)

    MD -2.45Low-quality journalMain outcomeOpen-label
    Quasi ExperimentalCpositiven=4040% confidence2005

    Influence of alternate nostril breathing on cardiorespiratory and autonomic functions in healthy young adults.

    After 8 wks of ANB training... HR (63.20 +/- 11.11, P<0.001)

    Main outcomeOpen-labelNo control group
    Quasi ExperimentalCpositiven=2060% confidence2014

    Differential effects of uninostril and alternate nostril pranayamas on cardiovascular parameters and reaction time.

    HR reduced significantly following both CB and CN

    Weak journalMain outcomeOpen-labelCompleters only
    +2 more in Sources
    Open Resting Heart Rate Improvement
    →

    Breathwork in general: Medium · 3 trials →

  3. Anxiety ReductionCertaintyMediumSourceClinical8 cited studies · 2 other sources

    Findings are mixed: a 2013 randomized trial of 96 participants reported improved anxiety scores, while a 2025 randomized trial of 68 found a non-significant decrease in anxiety scores after follow-up, both within the test group and compared with the control group.

    What the sources found

    8 positive · 2 neutral · 0 negativeconfidence 52/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people and patients
    • Anxiety Disorder
    • Glaucoma
    • Hypertension (High Blood Pressure)
    • Parkinson's Disease

    Where the evidence comes from

    • Article8
    • Expert opinion1
    • Community reports1

    Protocol behind this outcome

    4 protocolsEstimated

    What the studies reporting this result did.

    Per week
    150 min
    Intensity
    Low
    Format
    Group
    Supervision
    Instructor-led

    Courses and single sessions · 3 repeated-course and 1 single-session protocols

    What worked in trials4 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session15 min23 min
    How often5×/week10.5×/week

    Trials that found no benefit ran2 trials and meta-analyses

    SmallestTypical
    Session12 min14 min
    Derived from (4)

    28601355372902194107924041765327

    Timing

    Trials that found it typically ran 4 weeks

    While several RCTs and quasi-experimental studies report significant reductions in anxiety with alternate nostril breathing, one RCT in hypertensive patients (PMID 40242728) found non-significant effects on anxiety at follow-up. The overall evidence is mixed but leans positive.

    Show studies (10)
    RCTCpositiven=9645% confidence2013

    Effect of short-term practice of pranayamic breathing exercises on cognition, anxiety, general well being and heart rate variability.

    There was also highly significant improvement of cognition, general well being and anxiety as shown by the PGI memory scale, Hamilton- anxiety scale and psychological general well being schedule scores in this group.

    Main outcomeOpen-label
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    Significant decrease in depression, anxiety, stress levels, negative affect... in the test group compared to the control group.

    Weak journalOpen-labelInactive control
    RCTCneutraln=6840% confidence2025

    An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.

    After follow-up intervention, in the test group, there was a non-significant decrease in PSQI and HAM-A from baseline. After follow-up intervention, there was a non-significant decrease in PSQI and HAM-A of the test group, in comparison to the control group.

    MD -1Weak journalOpen-labelInactive controlCompleters only25% dropped outBorderline p-value
    RCTCpositiven=6055% confidence2023

    Effect of alternate nostril breathing exercise on autonomic functions, ocular hypertension, and quality of life in elderly with systemic hypertension and high-tension primary open-angle glaucoma.

    hospital anxiety and depression scale (HADS-A)... All measurements were improved in the ANBE group only. (HADS is inverted: a decrease is an improvement.)

    Inactive control
    RCTCpositiven=4560% confidence2026

    Short-Term Effects of Nostril-Regulated Yoga Breathing on Autonomic Variables: A Randomized Crossover Trial.

    State-Trait Anxiety Inventory scores decreased after right-uninostril breathing, left-uninostril breathing, alternate-nostril breathing, and quiet rest in right-nostril dominance at rest and left-nostril dominance at rest (padj < 0.05 in all cases)

    RCTCneutraln=3040% confidence2017

    Effect of Alternate Nostril Breathing Exercise on Experimentally Induced Anxiety in Healthy Volunteers Using the Simulated Public Speaking Model: A Randomized Controlled Pilot Study.

    Repeated-measures ANOVA showed a significant effect of phase (F_4,112 = 5.283; p = 0.001) but not group or phase by group interaction. The anxiety scores (mean ± SD) for the test and the control groups during the prestress, anticipatory, speech performance, and poststress phases were 9.96 ± 4.98 ver

    Low-quality journalMain outcomeOpen-labelCompleters only
    +4 more in Sources
    Open Anxiety Reduction
    →

    Breathwork in general: Medium · 23 trials →

  4. Improve Heart Rate Variability (HRV)CertaintyMediumSourceClinical8 cited studies · 1 other source

    A 2023 randomized trial of 100 participants found an increase in RMSSD, a time-domain measure of heart rate variability, of MD 7.36 ms. Another randomized trial reported increased high-frequency and decreased low-frequency components and LF/HF among people practising pranayama.

    What the sources found

    6 positive · 3 neutral · 0 negativeconfidence 52/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people and patients
    • Anxiety Disorder
    • Hypertension (High Blood Pressure)
    • Parkinson's Disease

    Where the evidence comes from

    • Article8
    • Expert opinion1

    Protocol behind this outcome

    5 protocolsEstimated

    What the studies reporting this result did.

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Courses and single sessions · 2 repeated-course and 3 single-session protocols

    What worked in trials3 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session12 min15 min
    How often7×/week10.5×/week
    Per week84 min147 min

    Trials that found no benefit ran3 trials and meta-analyses

    SmallestTypical
    Session10 min15 min
    Derived from (3)

    374995904024272841079240

    Timing

    A trial found it after a single session

    Trials that found it ran as little as 6 weeks, typically 9

    Show studies (9)
    RCTCpositiven=10055% confidence2023

    Effects of Nadishodhana and Bhramari Pranayama on heart rate variability, auditory reaction time, and blood pressure: A randomized clinical trial in hypertensive patients.

    In the time domain of heart rate variability, there was a significant increase in RMSSD (p = 0.029)

    MD 7.36Main outcomeOpen-labelAllocation not hiddenCompleters onlyBorderline p-value
    RCTCpositiven=9650% confidence2013

    Effect of short-term practice of pranayamic breathing exercises on cognition, anxiety, general well being and heart rate variability.

    The results showed highly significant increase in high frequency (HF) components of heart rate variability and decrease in low frequency (LF) components and LF/HF in the group practising pranayam.

    Main outcomeOpen-label
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    The test group revealed significantly high total HRV (SDNN, total power) and HRV indices of cardiac parasympathetic activity (RMSSD, pNN50, HF power, HF normalized unit) and significantly low HRV indices of cardiac sympathetic activity (LF normalized unit) and cardiac sympathovagal balance (LF/HF ra

    Weak journalMain outcomeOpen-labelInactive control
    RCTCpositiven=6870% confidence2025

    An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.

    After follow-up intervention, in the test group, there was a non-significant decrease in MHR, increase in R-R interval, increase in RMSSD and a significant increase in SDNN in comparison to the control group.

    MD 13.95Weak journalOpen-labelInactive controlCompleters only25% dropped out
    RCTCneutraln=4535% confidence2026

    Short-Term Effects of Nostril-Regulated Yoga Breathing on Autonomic Variables: A Randomized Crossover Trial.

    In right-nostril dominance at rest RMSSD and high-frequency heart rate variability increased during left-uninostril breathing; no significant change was reported for alternate-nostril breathing in the abstract

    RCTCneutraln=3435% confidence2026

    Acute Psychophysiological Effects Of 4-7-8 And Nadi Shodhana Breathing: A Randomized Crossover Study.

    No significant main effects of condition were observed for conventional HRV indices... No other HRV effects reached statistical significance.

    Blinded assessor
    +3 more in Sources
    Open Improve Heart Rate Variability (HRV)
    →

    Breathwork in general: Medium · 10 trials →

  5. Cognitive Function ImprovementCertaintyMediumSourceClinical4 cited studies · 1 other source

    A 2019 randomized trial of 50 participants found that errors on a shape and size discrimination task fell by -33.1% after an Alternate Nostril Breathing session. A 2025 randomized trial also reported improved cognition in the test group.

    What the sources found

    5 positive · 0 neutral · 0 negativeconfidence 57/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from High to Medium after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people and patients
    • Parkinson's Disease

    Where the evidence comes from

    • Article4
    • Community reports1

    Protocol behind this outcome

    3 protocolsEstimated

    What the studies reporting this result did.

    7.5×/week

    Course
    10 weeks
    Per week
    110 min
    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Courses and single sessions · 2 repeated-course and 1 single-session protocols

    What worked in trials2 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session15 min17 min
    Derived from (2)

    3100676741079240

    Timing

    A trial found it after a single session

    Show studies (5)
    RCTCpositiven=5060% confidence2019

    Changes in Shape and Size Discrimination and State Anxiety After Alternate-Nostril Yoga Breathing and Breath Awareness in One Session Each.

    The errors scores in the shape and size discrimination task showed a significant reduction after the ANYB session (p<0.001).

    -33.1%Large effectWeak journalMain outcomeBlinded assessor
    RCTCpositiven=2045% confidence2007

    Immediate effect of three yoga breathing techniques on performance on a letter-cancellation task.

    The letter-cancellation task scores were significantly improved, i.e., there were fewer errors following right and alternate nostril yoga breathing (Wilcoxon paired signed-ranks test).

    Main outcomeOpen-labelSham comparison
    Quasi ExperimentalCpositiven=14055% confidence2021

    The Effect of Pranayamic Breathing as a Positive Psychology Exercise on Foreign Language Learning Anxiety and Test Anxiety Among Language Learners at Tertiary Level.

    A statistically significant change was observed between pre- and post-test LRCT scores (z = 2.0, p = 0.041) for the experimental group.

    Weak journalOpen-labelInactive control
    Community reportsmoderate effectpositive50% confidence

    This effect was mentioned in 13 of 266 Reddit reports discussing it.

    13 mentions
    Open Cognitive Function Improvement
    →

    Breathwork in general: Medium · 4 trials →

  6. Reaction Speed IncreaseCertaintyMediumSourceClinical3 cited studies

    An RCT of 100 participants found a decrease in auditory reaction time of MD -0.66 seconds. In a separate RCT, reaction time in the 2-back task decreased by -8.59% immediately after Alternate Nostril Breathing.

    What the sources found

    3 positive · 0 neutral · 0 negativeconfidence 67/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from High to Medium after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people and patients
    • Diabetes Type2
    • Hypertension (High Blood Pressure)
    • Hypothyroidism

    Where the evidence comes from

    • Article3

    Protocol behind this outcome

    3 protocolsMeasured

    What the studies reporting this result did.

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Single sessions · 0 repeated-course and 3 single-session protocols

    What worked in trials2 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session15 min18 min
    Derived from (2)

    3618629137499590

    Timing

    A trial found it after a single session

    Show studies (3)
    RCTCpositiven=10070% confidence2023

    Effects of Nadishodhana and Bhramari Pranayama on heart rate variability, auditory reaction time, and blood pressure: A randomized clinical trial in hypertensive patients.

    There was a significant decrease in the ART (p < 0.00001).

    MD -0.66Open-labelAllocation not hiddenCompleters only
    RCTCpositiven=4070% confidence2022

    Slow yoga breathing improves mental load in working memory performance and cardiac activity among yoga practitioners.

    significant reduction in reaction time (ms) in 2-back condition immediately after ANB (−8%)

    -8.59%Small effectWeak journalMain outcomeOpen-labelBorderline p-value
    Quasi ExperimentalCpositiven=2060% confidence2014

    Differential effects of uninostril and alternate nostril pranayamas on cardiovascular parameters and reaction time.

    ART and VRT shortened significantly following SB and SN

    Weak journalMain outcomeOpen-labelCompleters only
    Open Reaction Speed Increase
    →

    Breathwork in general: Medium · 3 trials →

  7. Cardiovascular Health SupportCertaintyMediumSourceClinical5 cited studies

    A 2024 randomized trial of 100 participants reported reductions in heart rate, systolic and diastolic blood pressure, mean arterial pressure, and rate pressure product after the intervention.

    What the sources found

    4 positive · 1 neutral · 0 negativeconfidence 54/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people and patients
    • Diabetes Type2
    • Hypertension (High Blood Pressure)
    • Hypothyroidism

    Where the evidence comes from

    • Article5

    Protocol behind this outcome

    3 protocolsMeasured

    What the studies reporting this result did.

    20 min

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Single sessions · 0 repeated-course and 3 single-session protocols

    Show studies (5)
    RCTCneutraln=16455% confidence2022

    The Effect of Specific Techniques of Nasal Breathing [Pranayama] on Intra-Ocular Pressure in Normal Individuals, a Randomized Trial.

    In the LNB and NB groups, there was statistically significant reduction in the pulse rate (Table 3).

    MD -0.9Top journalBlinded assessor
    RCTCpositiven=10055% confidence2024

    Effects of an 8-week intervention of anulom vilom pranayama combined with heartfulness meditation on psychological stress, autonomic function, inflammatory biomarkers, and oxidative stress in healthcare workers during COVID-19 pandemic: a randomized controlled trial.

    AVPHFN intervention resulted in a significant reduction in cardiovascular parameters heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure and rate pressure product (p

    Open-labelInactive control
    Quasi ExperimentalCpositiven=4160% confidence2014

    Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness.

    A significant increase (p<0.001) was observed in the mean RR interval after the ANYB session with 95% CI of [−0.023, −0.094] compared with the respective pre values.

    Weak journalOpen-labelCompleters only
    Quasi ExperimentalCpositiven=4040% confidence2005

    Influence of alternate nostril breathing on cardiorespiratory and autonomic functions in healthy young adults.

    After 8 wks of ANB training... HR (63.20 +/- 11.11, P<0.001)

    Main outcomeOpen-labelNo control group
    Quasi ExperimentalCpositiven=2060% confidence2014

    Differential effects of uninostril and alternate nostril pranayamas on cardiovascular parameters and reaction time.

    significant reduction in RPP and Double product (DoP) following CB and CN, while only RPP decreased significantly following NS

    Weak journalMain outcomeOpen-labelCompleters only
    Open Cardiovascular Health Support
    →

    Breathwork in general: Medium · 5 trials →

Medium probability(3)
  1. Stress Resilience ImprovementCertaintyMediumSourceClinical3 cited studies · 2 other sources

    A 2025 randomized trial of 86 people with Parkinson's disease reported decreases in depression, anxiety, stress, and negative affect in the test group compared with the control group. A separate 2024 trial assessed psychological stress and concluded that its breathing module may help curtail stress and improve well-being.

    What the sources found

    5 positive · 0 neutral · 0 negativeconfidence 52/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Parkinson's Disease

    Where the evidence comes from

    • Article3
    • Expert opinion1
    • Community reports1

    Protocol behind this outcome

    3 protocolsEstimated

    What the studies reporting this result did.

    7×/week

    Per week
    150 min
    Intensity
    Low
    Format
    Group
    Supervision
    Instructor-led

    A repeated course

    What worked in trials3 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session10 min13 min
    Derived from (3)

    393316084107924042771122

    Timing

    A trial found it after a single session

    Trials that found it ran as little as 8 weeks, typically 10

    Show studies (5)
    RCTCpositiven=10045% confidence2024

    Effects of an 8-week intervention of anulom vilom pranayama combined with heartfulness meditation on psychological stress, autonomic function, inflammatory biomarkers, and oxidative stress in healthcare workers during COVID-19 pandemic: a randomized controlled trial.

    psychological stress using the questionnaire were assessed; Conclusions: ...AVPHFN module may be beneficial for curtailing stress and improving well-being.

    Open-labelInactive control
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    Significant decrease in depression, anxiety, stress levels, negative affect... in the test group compared to the control group.

    Weak journalOpen-labelInactive control
    RCTCpositiven=3440% confidence2026

    Acute Psychophysiological Effects Of 4-7-8 And Nadi Shodhana Breathing: A Randomized Crossover Study.

    Significant condition × sex interactions were observed for subjective outcomes... whereas Nadi Shodhana showed greater reductions in men. (Instruments: Perceived Stress Scale (PSS), PANAS, VAS; PSS is inverted, so a decrease is positive.)

    Main outcomeBlinded assessor
    Expert opinionpositive50% confidence

    This practice is used as a core technique for enhancing stress resilience through vagal modulation and cortisol regulation.

    Expert knowledge synthesis
    Community reportsmoderate effectpositive50% confidence

    This effect was mentioned in 9 of 266 Reddit reports discussing it.

    9 mentions
    Open Stress Resilience Improvement
    →

    Breathwork in general: Medium · 12 trials →

  2. Mood ImprovementCertaintyMediumSourceClinical2 cited studies · 1 other source

    A 2025 randomized trial reported improved positive affect after 12 weeks in people with Parkinson's disease in the test group compared with the control group.

    What the sources found

    3 positive · 0 neutral · 0 negativeconfidence 57/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Anxiety Disorder
    • Parkinson's Disease

    Where the evidence comes from

    • Article2
    • Community reports1

    Protocol behind this outcome

    2 protocolsEstimated

    What the studies reporting this result did.

    18 min · 10.5×/week

    Course
    9 weeks
    Per week
    179 min
    Intensity
    Low
    Format
    Individual

    A repeated course

    Show studies (3)
    RCTCpositiven=9645% confidence2013

    Effect of short-term practice of pranayamic breathing exercises on cognition, anxiety, general well being and heart rate variability.

    There was also highly significant improvement of cognition, general well being and anxiety as shown by the PGI memory scale, Hamilton- anxiety scale and psychological general well being schedule scores in this group.

    Main outcomeOpen-label
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    Significant improvement in positive affect... was noted at the end of 12 weeks in PD patients of the test group compared to those in the control group.

    Weak journalOpen-labelInactive control
    Community reportsmoderate effectpositive50% confidence

    This effect was mentioned in 22 of 266 Reddit reports discussing it.

    22 mentions
    Open Mood Improvement
    →

    Breathwork in general: Medium · 16 trials →

  3. Physical Strength IncreaseCertaintyMediumSourceClinical2 cited studies

    In a 1997 randomized trial of 130 participants, grip strength in both hands increased by 4.1% to 6.5% after right-, left-, or alternate-nostril breathing, with no difference between sides.

    What the sources found

    2 positive · 0 neutral · 0 negativeconfidence 50/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people
    • Shift Work Disorder

    Where the evidence comes from

    • Article2

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    15 min

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Single sessions · 0 repeated-course and 1 single-session protocols

    Show studies (2)
    RCTCpositiven=13040% confidence1997

    Pranayama increases grip strength without lateralized effects.

    The right-, left- and alternate-nostril breathing groups had a significant increase in grip strength of both hands, ranging from 4.1% to 6.5%, at the end of the camp though without any lateralization effect.

    Main outcomeOpen-label
    Cross SectionalCpositiven=28060% confidence2021

    Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers.

    MS/HGS (kg) 23.83±8.16 to 27.34±8.49, P=0.000 (Group I); 23.38±9.639 to 24.09±9.82, P=0.012 (Group II)

    MD 3.51Small effectLow-quality journalMain outcomeOpen-label
    Open Physical Strength Increase
    →

    Breathwork in general: Low · 6 trials →

Low probability(16)
  1. Respiratory Health SupportCertaintyLowSourceClinical7 cited studies · 1 other source

    In a 2021 randomized trial of 100 participants, FVC rose from 3.342 to 3.691 L in males (P=0.008) and from 2.381 to 2.702 L in females (P=0.001) in the experimental group.

    What the sources found

    8 positive · 0 neutral · 0 negativeconfidence 49/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from Medium to Low after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people and patients
    • Shift Work Disorder

    Where the evidence comes from

    • Article7
    • Community reports1

    Protocol behind this outcome

    3 protocolsEstimated

    What the studies reporting this result did.

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Courses and single sessions · 2 repeated-course and 1 single-session protocols

    What worked in trials2 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session10 min20 min
    How often5×/week6×/week
    Per week70 min110 min
    Derived from (2)

    2860135534213471

    Timing

    Trials that found it typically ran 4 weeks

    Show studies (8)
    RCTCpositiven=10060% confidence2021

    Effects of alternate nostril breathing exercise on cardiorespiratory functions in healthy young adults.

    FVC (L): males 3.342 to 3.691 (P=0.008), females 2.381 to 2.702 (P=0.001) in experimental group

    Weak journalMain outcomeOpen-labelNo control group
    RCTCpositiven=2760% confidence2017

    Yogic breathing practices improve lung functions of competitive young swimmers.

    ANCOVA test showed a significant improvement in Maximum Voluntary Ventilation (MVV) (F_(1,22) = 6.06, p = 0.02)

    Main outcomeOpen-labelInactive controlCompleters only
    Cross SectionalCpositiven=28060% confidence2021

    Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers.

    RR (breaths/min) 15.21±2.92 to 14.45±2.61, P=0.003 (Group I); 15.41±2.99 to 14.37±2.537, P=0.000 (Group II)

    MD -0.76Low-quality journalMain outcomeOpen-label
    Quasi ExperimentalCpositiven=13570% confidence2024

    The Impact of Yogic Breathing Exercises on Pulmonary Functions in Asymptomatic Smokers.

    BHTi (seconds) 36.15 ± 8.61 to 50.16 ± 12.94, p=0.0001

    MD 14.01Low-quality journalOpen-labelNo control groupCompleters only
    Quasi ExperimentalCpositiven=4040% confidence2005

    Influence of alternate nostril breathing on cardiorespiratory and autonomic functions in healthy young adults.

    After 8 wks of ANB training RR (12.35 +/- 1.35, P<0.0001)... declined to much greater extent

    Main outcomeOpen-labelNo control group
    Quasi ExperimentalCpositiven=2030% confidence1984

    A study of yoga as a nursing intervention in the care of patients with pleural effusion.

    The results revealed that the patients practising Pranayama demonstrated a quicker re-expansion of the lungs in most of the measures of lung function.

    Top journalMain outcomeOpen-label
    +2 more in Sources
    Open Respiratory Health Support
    →

    Breathwork in general: Medium · 41 trials →

  2. Lung Capacity ImprovementCertaintyLowSourceClinical6 cited studies

    In a 2021 randomized trial of 100 participants, FVC rose from 3.342 to 3.691 L in males (P=0.008) and from 2.381 to 2.702 L in females (P=0.001). A 2024 quasi-experimental study of 135 participants reported that PEFR rose from 6.98 ± 1.52 to 7.64 ± 1.48 L/sec (MD 0.66 L/sec).

    What the sources found

    6 positive · 0 neutral · 0 negativeconfidence 51/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from Medium to Low after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people and patients
    • Shift Work Disorder

    Where the evidence comes from

    • Article6

    Protocol behind this outcome

    2 protocolsEstimated

    What the studies reporting this result did.

    15 min · 10.5×/week

    Course
    5 weeks
    Per week
    158 min
    Intensity
    Low
    Format
    Individual

    A repeated course

    Show studies (6)
    RCTCpositiven=10060% confidence2021

    Effects of alternate nostril breathing exercise on cardiorespiratory functions in healthy young adults.

    FVC (L): males 3.342 to 3.691 (P=0.008), females 2.381 to 2.702 (P=0.001) in experimental group

    Weak journalMain outcomeOpen-labelNo control group
    Cross SectionalCpositiven=28060% confidence2021

    Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers.

    PEFR (L/min) 295.26±118.38 to 338.70±117.34, P=0.000 (Group I); 316.93±123.311 to 357.93±120.76, P=0.000 (Group II)

    MD 43.44Low-quality journalMain outcomeOpen-label
    Quasi ExperimentalCpositiven=13565% confidence2024

    The Impact of Yogic Breathing Exercises on Pulmonary Functions in Asymptomatic Smokers.

    PEFR (L/sec) 6.98 ± 1.52 to 7.64 ± 1.48, p=0.0001

    MD 0.66Low-quality journalOpen-labelNo control groupCompleters only
    Quasi ExperimentalCpositiven=10045% confidence2020

    Effects of alternate nostril breathing exercise on respiratory functions in healthy young adults leading stressful lifestyle.

    The mean value of FVC, FEV 1 , PEFR were significantly (P < 0.001) changed after the ANB exercise when compared to the values before breathing exercise.

    Main outcomeNo control group
    Quasi ExperimentalCpositiven=4040% confidence2005

    Influence of alternate nostril breathing on cardiorespiratory and autonomic functions in healthy young adults.

    PEFR (571.50 +/- 46.26, P<0.01) rose significantly

    Open-labelNo control group
    Quasi ExperimentalCpositive35% confidence2008

    Effect of alternate nostril breathing exercise on cardiorespiratory functions.

    A significant increment in Peak expiratory flow rate (PEFR L/min) and Pulse pressure (PP) was noted.

    Main outcomeOpen-labelNo control group
    Open Lung Capacity Improvement
    →

    Breathwork in general: Medium · 22 trials →

  3. Homocysteine Level ReductionCertaintyLowSourceClinical1 cited study

    An RCT of 86 participants with Parkinson's Disease reported lower serum homocysteine and serum 8-OHdG in the test group compared with the control group. The finding does not provide the size of either change.

    What the sources found

    1 positive · 0 neutral · 0 negativeconfidence 75/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Parkinson's Disease

    Where the evidence comes from

    • Article1

    Protocol behind this outcome

    1 protocolEstimated

    What the studies reporting this result did.

    15 min · 14×/week

    Course
    12 weeks
    Per week
    210 min
    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    A repeated course

    Show studies (1)
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    Significant decrease in... serum HCY and serum 8-OHdG... in the test group compared to the control group.

    Weak journalOpen-labelInactive control
    Open Homocysteine Level Reduction
    →
  4. Migraine ReliefCertaintyLowSourceClinical1 cited study

    An RCT of 86 participants with a clinical condition found that the intervention group had fewer migraine attacks than the control group. The finding concerns attack frequency; it does not establish effects on other migraine outcomes.

    What the sources found

    1 positive · 0 neutral · 0 negativeconfidence 70/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition

    Where the evidence comes from

    • Article1

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    21×/week

    Course
    13 weeks
    Format
    Individual
    Supervision
    Self-guided

    A repeated course

    Show studies (1)
    RCTCpositiven=8670% confidence2025

    The impact of alternate nostril breathing on the severity and frequency of migraine attacks: a randomized control trial.

    The intervention group showed a significant reduction in migraine attack frequency (*P* = 0.002) compared to the control group.

    Top journalMain outcomeOpen-labelInactive controlAllocation not hidden
    Open Migraine Relief
    →
  5. Respiratory Rate OptimizationCertaintyLowSourceClinical3 cited studies · 1 other source

    In a quasi-experimental study of 41 participants, respiratory rate decreased during and after Alternate Nostril Breathing compared with pre-intervention values. A separate quasi-experimental study also reported a decrease in respiratory rate among healthy participants.

    What the sources found

    4 positive · 0 neutral · 0 negativeconfidence 48/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from Medium to Low after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people

    Where the evidence comes from

    • Article3
    • Community reports1

    Protocol behind this outcome

    2 protocolsMeasured

    What the studies reporting this result did.

    20 min

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Single sessions · 0 repeated-course and 2 single-session protocols

    Show studies (4)
    Cross SectionalCpositiven=28060% confidence2021

    Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers.

    RR (breaths/min) 15.21±2.92 to 14.45±2.61, P=0.003 (Group I); 15.41±2.99 to 14.37±2.537, P=0.000 (Group II)

    MD -0.76Low-quality journalMain outcomeOpen-label
    Quasi ExperimentalCpositiven=4170% confidence2014

    Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness.

    There was a significant decrease in the respiration rate during ANYB (p<0.001) with 95% CI of [5.205, 2.309] and after ANYB (p<0.001) with 95% CI of [2.265, 0.531] compared with pre-intervention values.

    Weak journalOpen-labelCompleters only
    Quasi ExperimentalCpositive35% confidence2008

    Effect of alternate nostril breathing exercise on cardiorespiratory functions.

    the decrease in pulse rate (PR), respiratory rate (RR), diastolic blood pressure (DBP) were significant.

    Open-labelNo control group
    Community reportsmoderate effectpositive25% confidence

    This effect was mentioned in 2 of 266 Reddit reports discussing it.

    2 mentions
    Open Respiratory Rate Optimization
    →

    Breathwork in general: Medium · 4 trials →

  6. Working Memory ImprovementCertaintyLowSourceClinical1 cited study

    An RCT of 40 healthy participants found accuracy in the 2-back condition improved by 6.62% after Alternate Nostril Breathing. The reported change was specific to this working-memory task.

    What the sources found

    1 positive · 0 neutral · 0 negativeconfidence 70/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people

    Where the evidence comes from

    • Article1

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    15 min

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Single sessions · 0 repeated-course and 1 single-session protocols

    Timing

    A trial found it after a single session

    Show studies (1)
    RCTCpositiven=4070% confidence2022

    Slow yoga breathing improves mental load in working memory performance and cardiac activity among yoga practitioners.

    accuracy was improved in the 2-back condition after ANB (6%)

    6.62%Small effectWeak journalMain outcomeOpen-labelBorderline p-value
    Open Working Memory Improvement
    →
  7. Eye and Vision Health SupportCertaintyLowSourceClinical2 cited studies

    A 2023 randomized trial of 60 participants reported improvement in all measured outcomes in the Alternate Nostril Breathing exercise group only; measurements included right-eye intraocular pressure.

    What the sources found

    1 positive · 1 neutral · 0 negativeconfidence 58/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people and patients
    • Glaucoma
    • Hypertension (High Blood Pressure)

    Where the evidence comes from

    • Article2

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    Course
    13 weeks

    A repeated course

    Show studies (2)
    RCTCneutraln=16460% confidence2022

    The Effect of Specific Techniques of Nasal Breathing [Pranayama] on Intra-Ocular Pressure in Normal Individuals, a Randomized Trial.

    In ANB, there was no significant change in the IOP in either eye after the breathing exercise (Table 2).

    MD 0.2Top journalMain outcomeBlinded assessor
    RCTCpositiven=6055% confidence2023

    Effect of alternate nostril breathing exercise on autonomic functions, ocular hypertension, and quality of life in elderly with systemic hypertension and high-tension primary open-angle glaucoma.

    All measurements were improved in the ANBE group only... Right-eye intraocular pressure (IOP)... were assessed.

    Main outcomeInactive control
    Open Eye and Vision Health Support
    →
  8. Antidepressant EffectCertaintyLowSourceClinical2 cited studies · 1 other source

    A 2025 randomized trial of 86 people with Parkinson's disease reported decreases in depression, anxiety, stress, and negative affect in the test group compared with the control group. In a separate trial of 60 participants with glaucoma and hypertension, measurements on the Hospital Anxiety and Depression Scale improved in the breathing exercise group only.

    What the sources found

    3 positive · 0 neutral · 0 negativeconfidence 52/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Why this rating

    • A reviewer set it to Low · Keep low. Both supporting RCTs are small, open-label and use passive controls: PMID 41079240 (Parkinson's, n=86, vs usual care) and PMID 37290219 (hypertension + glaucoma, n=60, vs waitlist). In both, depression is a secondary outcome in people not selected for depression, so the evidence is too weak for medium as an antidepressant claim.

    Who was studied

    • People with a condition
    • Glaucoma
    • Hypertension (High Blood Pressure)
    • Parkinson's Disease

    Where the evidence comes from

    • Article2
    • Community reports1

    Protocol behind this outcome

    1 protocolEstimated

    What the studies reporting this result did.

    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    A repeated course

    What worked in trials2 trials and meta-analyses

    Randomized trials and meta-analyses that found this benefit: the smallest and the typical amount. Not a target and not a limit.

    SmallestTypical
    Session15 min23 min
    How often14×/week
    Per week210 min315 min
    Derived from (2)

    3729021941079240

    Timing

    Trials that found it ran as little as 4 weeks, typically 8

    Show studies (3)
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    Significant decrease in depression, anxiety, stress levels, negative affect... in the test group compared to the control group.

    Weak journalOpen-labelInactive control
    RCTCpositiven=6055% confidence2023

    Effect of alternate nostril breathing exercise on autonomic functions, ocular hypertension, and quality of life in elderly with systemic hypertension and high-tension primary open-angle glaucoma.

    hospital anxiety and depression scale (HADS-D)... All measurements were improved in the ANBE group only. (HADS is inverted: a decrease is an improvement.)

    Inactive control
    Community reportsmoderate effectpositive25% confidence

    This effect was mentioned in 2 of 266 Reddit reports discussing it.

    2 mentions
    Open Antidepressant Effect
    →

    Breathwork in general: Medium · 16 trials →

  9. Analgesic EffectCertaintyLowSourceClinical2 cited studies

    In a 2025 randomized trial of 69 people undergoing hemodialysis, average pain intensity after breathing exercises was 0.4 ± 1.19 in the experimental group and 4.06 ± 3.1 in the control group. A 2014 randomized trial reported that Jala Neti, Pranayama and Trataka therapy was equally effective as Headache Saptamrata Lauha therapy.

    What the sources found

    2 positive · 0 neutral · 0 negativeconfidence 58/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from Medium to Low after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • People with a condition
    • Chronic Kidney Disease

    Where the evidence comes from

    • Article2

    Timing

    Trials that found it ran as little as 8 weeks, typically 11

    Show studies (2)
    RCTCpositiven=6965% confidence2025

    The effect of breathing exercises on pain, sleep, and symptom management in patients undergoing hemodialysis: a randomized controlled trial.

    Following the application, the average pain intensity in the control group (4.06 ± 3.1) was found to be statistically significantly higher than the average in the experimental group (0.4 ± 1.19) (p... Visual Analog Scale (VAS) is inverted: a decrease is an improvement.

    Top journalMain outcomeOpen-labelInactive control
    RCTCpositiven=6050% confidence2014

    Comparative study on the effect of Saptamrita Lauha and Yoga therapy in myopia.

    In Headache Saptamrata Lauha therapy (Group A) and Jala Neti, Pranayama and Trataka therapy (Group B) were equally effective (P < 0.005)

    Low-quality journalOpen-label
    Open Analgesic Effect
    →

    Breathwork in general: Medium · 15 trials →

  10. Sleep Quality ImprovementCertaintyLowSourceClinical2 cited studies · 2 other sources

    A 2025 randomized trial of 69 people undergoing hemodialysis reported improved sleep quality after breathing exercises. In another 2025 trial of 68, the decrease in sleep questionnaire scores at follow-up was not statistically significant, either from baseline or compared with the control group.

    What the sources found

    3 positive · 1 neutral · 0 negativeconfidence 46/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Chronic Kidney Disease
    • Hypertension (High Blood Pressure)

    Where the evidence comes from

    • Article2
    • Expert opinion1
    • Community reports1
    Show studies (4)
    RCTCpositiven=6955% confidence2025

    The effect of breathing exercises on pain, sleep, and symptom management in patients undergoing hemodialysis: a randomized controlled trial.

    Breathing exercises in patients undergoing hemodialysis were found to reduce pain, improve sleep quality, and have a positive impact on symptom management. (Measured with the Richards-Campbell Sleep Questionnaire, where higher scores indicate better sleep.)

    Top journalOpen-labelInactive control
    RCTCneutraln=6840% confidence2025

    An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.

    After follow-up intervention, in the test group, there was a non-significant decrease in PSQI and HAM-A from baseline. After follow-up intervention, there was a non-significant decrease in PSQI and HAM-A of the test group, in comparison to the control group.

    MD -1Trivial effectWeak journalOpen-labelInactive controlCompleters only25% dropped outBorderline p-value
    Expert opinionpositive50% confidence

    Slow breathing practices like alternate nostril breathing are used as a non-pharmacological intervention for improving sleep quality.

    Expert knowledge synthesis
    Community reportsmoderate effectpositive40% confidence

    This effect was mentioned in 5 of 266 Reddit reports discussing it.

    5 mentions
    Open Sleep Quality Improvement
    →

    Breathwork in general: Medium · 13 trials →

  11. Memory ImprovementCertaintyLowSourceClinical4 cited studies

    A 2022 randomized trial found that accuracy in the 2-back condition improved by 6.62% after Alternate Nostril Breathing. A 2013 randomized trial also reported improvement on the PGI memory scale.

    What the sources found

    3 positive · 1 neutral · 0 negativeconfidence 44/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from Medium to Low after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people
    • Anxiety Disorder

    Where the evidence comes from

    • Article4

    Protocol behind this outcome

    3 protocolsEstimated

    What the studies reporting this result did.

    38 min · 7×/week

    Course
    1.2 weeks
    Per week
    315 min
    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Courses and single sessions · 2 repeated-course and 1 single-session protocols

    Timing

    A trial found it after a single session

    Show studies (4)
    RCTCneutraln=13525% confidence1997

    Yoga breathing through a particular nostril increases spatial memory scores without lateralized effects.

    It appears yoga breathing increases spatial rather than verbal scores, without a lateralized effect.

    Open-label
    RCTCpositiven=9645% confidence2013

    Effect of short-term practice of pranayamic breathing exercises on cognition, anxiety, general well being and heart rate variability.

    There was also highly significant improvement of cognition, general well being and anxiety as shown by the PGI memory scale, Hamilton- anxiety scale and psychological general well being schedule scores in this group.

    Main outcomeOpen-label
    RCTCpositiven=4070% confidence2022

    Slow yoga breathing improves mental load in working memory performance and cardiac activity among yoga practitioners.

    accuracy was improved in the 2-back condition after ANB (6%)

    6.62%Small effectWeak journalMain outcomeOpen-labelBorderline p-value
    Quasi ExperimentalCpositiven=5135% confidence2016

    Effect of Left, Right and Alternate Nostril Breathing on Verbal and Spatial Memory.

    Results showed that there was increase in recall of digit span-forward, digit-span backward, associate learning and spatial memory scores with RNB, LNB and ANB, which were statistically highly significant (Wechsler Adult Intelligence Scale)

    Main outcomeNo control group
    Open Memory Improvement
    →

    Breathwork in general: 1 trial →

  12. Vagal Tone ImprovementCertaintyLowSourceClinical1 cited study · 1 other source

    An RCT of 86 participants with Parkinson's Disease found higher total HRV and higher measures of cardiac parasympathetic activity in the test group than in the control group. These were measured as heart-rate variability indices rather than as a direct measurement of vagal tone.

    What the sources found

    2 positive · 0 neutral · 0 negativeconfidence 58/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Parkinson's Disease

    Where the evidence comes from

    • Article1
    • Community reports1

    Protocol behind this outcome

    1 protocolEstimated

    What the studies reporting this result did.

    15 min · 14×/week

    Course
    12 weeks
    Per week
    210 min
    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    A repeated course

    Show studies (2)
    RCTCpositiven=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    The test group revealed significantly high total HRV (SDNN, total power) and HRV indices of cardiac parasympathetic activity (RMSSD, pNN50, HF power, HF normalized unit)... compared to the control group.

    Weak journalMain outcomeOpen-labelInactive control
    Community reportsmoderate effectpositive40% confidence

    This effect was mentioned in 5 of 266 Reddit reports discussing it.

    5 mentions
    Open Vagal Tone Improvement
    →
  13. Chronic Pain ReductionCertaintyLowSourceClinical1 cited study · 1 other source

    A 2025 randomized trial of 86 people with migraine found that the intervention reduced migraine attack frequency compared with the control group.

    What the sources found

    2 positive · 0 neutral · 0 negativeconfidence 50/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Migraine

    Where the evidence comes from

    • Article1
    • Community reports1
    Show studies (2)
    RCTCpositiven=8670% confidence2025

    The impact of alternate nostril breathing on the severity and frequency of migraine attacks: a randomized control trial.

    The intervention group showed a significant reduction in migraine attack frequency (*P* = 0.002) compared to the control group.

    Top journalMain outcomeOpen-labelInactive controlAllocation not hidden
    Community reportssubtle effectpositive30% confidence

    This effect was mentioned in 3 of 266 Reddit reports discussing it.

    3 mentions
    Open Chronic Pain Reduction
    →

    Breathwork in general: 1 trial →

  14. Parasympathetic ActivationCertaintyLowSourceClinical1 cited study · 2 other sources

    A quasi-experimental study in healthy participants reported enhanced parasympathetic tone, assessed with an orthostatic tolerance test using the 30:15 ratio.

    What the sources found

    3 positive · 0 neutral · 0 negativeconfidence 43/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people

    Where the evidence comes from

    • Article1
    • Expert opinion1
    • Community reports1
    Show studies (3)
    Quasi ExperimentalCpositive30% confidence2013

    Assessment of the effects of pranayama/alternate nostril breathing on the parasympathetic nervous system in young adults.

    This study showed that the parasympathetic tone was enhanced appreciably in the participants. ... orthostatic tolerance test (30:15 ratio)

    Main outcomeOpen-labelNo control group
    Expert opinionpositive50% confidence

    Alternate Nostril Breathing directly increases parasympathetic nervous system activity via nasal cycle-brainstem-vagus nerve pathways.

    Expert knowledge synthesis
    Community reportsmoderate effectpositive50% confidence

    This effect was mentioned in 16 of 266 Reddit reports discussing it.

    16 mentions
    Open Parasympathetic Activation
    →
  15. Concentration ImprovementCertaintyLowSourceClinical1 cited study · 1 other source

    An RCT of 27 healthy participants found a reduction in self-reported concentration disruption within the group. The result reflects participants' reports, rather than an objective test of concentration.

    What the sources found

    2 positive · 0 neutral · 0 negativeconfidence 48/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people

    Where the evidence comes from

    • Article1
    • Community reports1

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    30 min · 5×/week

    Course
    4 weeks
    Per week
    150 min
    Intensity
    Low
    Format
    Group
    Supervision
    Instructor-led

    A repeated course

    Show studies (2)
    RCTCpositiven=2745% confidence2017

    Yogic breathing practices improve lung functions of competitive young swimmers.

    Paired t test done to assess within group changes show a significant reduction in self-reported ... Concentration Disruption (t = 2.635, p = 0.022)

    Open-labelInactive controlCompleters only
    Community reportsmoderate effectpositive50% confidence

    This effect was mentioned in 22 of 266 Reddit reports discussing it.

    22 mentions
    Open Concentration Improvement
    →

    Breathwork in general: 1 trial →

  16. Brain Fog ReductionCertaintyLowSourceAnecdotallong-termnot used for recommendations2 other sources

    Expert commentary proposes that changes in cerebral blood flow, oxygenation, and autonomic balance could reduce subjective brain fog. Some people have also reported this effect, but those reports are not clinical evidence.

    What the sources found

    2 positive · 0 neutral · 0 negativeconfidence 45/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Where the evidence comes from

    • Expert opinion1
    • Community reports1

    Why it isn't used for recommendations

    No supporting study on file

    Show studies (2)
    Expert opinionpositive45% confidence

    By improving cerebral blood flow, oxygenation, and autonomic balance, this practice can reduce subjective brain fog.

    Expert knowledge synthesis
    Community reportsmoderate effectpositive45% confidence

    This effect was mentioned in 6 of 266 Reddit reports discussing it.

    6 mentions
    Open Brain Fog Reduction
    →
Very low probability(1)
  1. Posture ImprovementCertaintyVery lowSourceClinicalnot used for recommendations1 cited study

    A quasi-experimental study of 40 healthy participants found that the studies did not support improved posture: craniovertebral angle changed from 42.95 ± 8.11° to 43.35 ± 8.23°, a difference that was not statistically significant (p = 0.83).

    What the sources found

    0 positive · 1 neutral · 0 negativeconfidence 45/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people

    Where the evidence comes from

    • Article1

    Why it isn't used for recommendations

    Studied, with no positive result

    Show studies (1)
    Quasi ExperimentalCneutraln=4045% confidence2026

    Effect of an Eight-Week Breathing Exercise Program on the Respiratory Function and Craniovertebral Angle in Dental Students: A Pre-test and Post-test Quasi-experimental Study.

    CVA did not change significantly (42.95 ± 8.11° pre-intervention vs 43.35 ± 8.23° post-intervention; p = 0.83)

    MD 0.4Low-quality journalMain outcomeOpen-labelNo control groupCompleters only
    Open Posture Improvement
    →

    Breathwork in general: Medium · 3 trials →

6 more mentioned only by users

What to expect

Some findings, including changes in blood pressure, heart rate variability, and cognitive function, were reported after a single session. Across trials, blood pressure and resting heart rate findings were also measured at the end of programmes lasting 0.7 to 4 weeks; anxiety findings were measured after 4 weeks. Heart rate variability and stress-resilience findings were measured after programmes lasting 6–9 weeks and 8–10 weeks, respectively. These are trial timelines, not guaranteed onset times.

Conditions it's used for

Complaints and diagnoses people take it for8 listed

Most likely to help, from the evidence we have

  1. Hypertension (High Blood Pressure)CertaintyMediumSourceRCT9 cited studies

    A meta-analysis of 15 randomized trials found that breathing exercises reduced SBP by −7.06 mmHg and DBP by −3.43 mmHg in hypertensive adults. A systematic review of 15 studies found improvements in blood pressure, lipid profiles, and inflammatory markers among hypertensive patients practicing yoga.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Rating adjusted

    Lowered from High to Medium after checking study quality: journal, risk of bias, trial size and design.

    Who was studied

    • Healthy people and patients
    • Diabetes Type2
    • Glaucoma
    • Heart Failure (CHF)
    • Hypertension (High Blood Pressure)
    • Hypothyroidism

    Protocol behind this outcome

    9 protocolsEstimated

    What the studies reporting this result did.

    15 min · 10.5×/week

    Course
    6 weeks
    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    Courses and single sessions · 5 repeated-course and 4 single-session protocols

    Show studies (9)
    Meta-analysisBn=109775% confidence2024

    Effect of breathing exercises on blood pressure and heart rate: A systematic review and meta-analysis.

    Meta-analysis of 15 RCTs showing significant reduction in SBP (−7.06 mmHg) and DBP (−3.43 mmHg) with breathing exercises in hypertensive adults.

    High risk of biasPooled RCTsStudies disagree (I² 90%)Inactive control
    Systematic reviewCn=130660% confidence2025

    Effects of yogic practices on physiological and biochemical parameters of hypertensive patients: A systematic review of clinical trials.

    Systematic review of 15 studies (5 RCTs, 10 clinical trials) showing significant improvements in blood pressure, lipid profiles, and inflammatory markers in hypertensive patients practicing yoga.

    RCTCn=17075% confidence2019

    Effect of alternate nostril breathing exercise on blood pressure, heart rate, and rate pressure product among patients with hypertension in JIPMER, Puducherry.

    RCT showing significant reductions in BP, heart rate, and rate pressure product after 5 days of alternate nostril breathing.

    Open-labelInactive control
    RCTCn=10060% confidence2023

    Effects of Nadishodhana and Bhramari Pranayama on heart rate variability, auditory reaction time, and blood pressure: A randomized clinical trial in hypertensive patients.

    Both Nadi Shodhana and Bhramari Pranayama significantly reduced SBP and DBP immediately after a single 20-minute session in patients with essential hypertension.

    Open-labelAllocation not hiddenCompleters only
    RCTCn=9065% confidence2013

    Blood pressure and Purdue pegboard scores in individuals with hypertension after alternate nostril breathing, breath awareness, and no intervention.

    Single RCT showing immediate reduction in systolic and diastolic blood pressure after 10 minutes of ANYB in 30 participants with essential hypertension.

    Blinded assessorCompleters only
    RCTCn=6870% confidence2025

    An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.

    RCT showing significant reductions in SBP and DBP immediately and after 6 weeks of daily practice in hypertensive patients on medication.

    Weak journalOpen-labelInactive controlCompleters only25% dropped out
    +3 more in Sources
    Open Hypertension (High Blood Pressure)
    →

    Breathwork in general: Medium · 8 trials →

Low probability(6)
  1. GlaucomaCertaintyLowSourceClinical2 cited studies

    A trial in 60 people with glaucoma found that the Alternate Nostril Breathing exercise group had improved IOP and glaucoma-related quality of life.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • Healthy people and patients
    • Glaucoma
    • Hypertension (High Blood Pressure)

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    5 min

    Single sessions · 0 repeated-course and 1 single-session protocols

    Show studies (2)
    RCTCn=6055% confidence2023

    Effect of alternate nostril breathing exercise on autonomic functions, ocular hypertension, and quality of life in elderly with systemic hypertension and high-tension primary open-angle glaucoma.

    Study population selected for HTF-POAG; ANBE associated with improved IOP and glaucoma quality of life in the ANBE group only.

    Inactive control
    Cross SectionalCno effectn=7320% confidence2021

    Can Breathing Exercise or Pranayama Affect the Intraocular Pressure in the Short-term?

    Authors conclude no short-term transient IOP effect of the exercise; the abstract does not give a separate glaucoma-specific result.

    Top journalNo control group
    Open Glaucoma
    →

    Breathwork in general: 1 trial →

  2. Kidney Disease (General)CertaintyLowSourceClinical1 cited study

    A randomized controlled trial involving 69 patients undergoing hemodialysis reported that breathing exercises reduced pain and improved sleep and symptoms in this group.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Kidney Disease (General)

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    Course
    8 weeks

    A repeated course

    Show studies (1)
    RCTCn=6955% confidence2025

    The effect of breathing exercises on pain, sleep, and symptom management in patients undergoing hemodialysis: a randomized controlled trial.

    Patients undergoing hemodialysis were the study population; breathing exercises were reported to reduce pain and improve sleep and symptoms in this group.

    Top journalOpen-labelInactive control
    Open Kidney Disease (General)
    →
  3. MigraineCertaintyLowSourceClinical1 cited study

    An RCT in 86 people with migraine found that Alternate Nostril Breathing reduced migraine frequency and MIDAS scores compared with usual care.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Migraine

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    21×/week

    Course
    13 weeks
    Format
    Individual
    Supervision
    Self-guided

    A repeated course

    Show studies (1)
    RCTCn=8670% confidence2025

    The impact of alternate nostril breathing on the severity and frequency of migraine attacks: a randomized control trial.

    RCT showing significant reduction in migraine frequency and MIDAS scores with ANB compared to usual care.

    Top journalOpen-labelInactive controlAllocation not hidden
    Open Migraine
    →

    Breathwork in general: 1 trial →

  4. Parkinson's DiseaseCertaintyLowSourceClinical1 cited study

    A randomized controlled trial involving 86 people with Parkinson's disease found improvements in cardiac autonomic balance, cognition, psychological status, and quality of life when the practice was used as an adjunctive therapy.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Parkinson's Disease

    Protocol behind this outcome

    1 protocolEstimated

    What the studies reporting this result did.

    15 min · 14×/week

    Course
    12 weeks
    Per week
    210 min
    Intensity
    Low
    Format
    Individual
    Supervision
    Instructor-led

    A repeated course

    Show studies (1)
    RCTCn=8675% confidence2025

    Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.

    RCT showing significant improvements in cardiac autonomic balance, cognition, psychological status, and QoL with AVP as adjunctive therapy.

    Weak journalOpen-labelInactive control
    Open Parkinson's Disease
    →

    Breathwork in general: 2 trials →

  5. Pleural EffusionCertaintyLowSourceClinical1 cited study

    A quasi-experimental study examined alternate nostril breathing after fluid aspiration in 10 patients with pleural effusion, using lung re-expansion as the measured outcome.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition

    Protocol behind this outcome

    1 protocolMeasured

    What the studies reporting this result did.

    Course
    2.9 weeks

    A repeated course

    Show studies (1)
    Quasi ExperimentalCn=2030% confidence1984

    A study of yoga as a nursing intervention in the care of patients with pleural effusion.

    Ten patients with pleural effusion practised alternate nostril breathing after fluid aspiration, and lung re-expansion was measured in this condition.

    Top journalOpen-label
    Open Pleural Effusion
    →
  6. InsomniaCertaintyLowSourceTheoreticalnot used for recommendations1 other source

    Integrative protocols recommend the practice as a non-pharmacological approach to insomnia, with the rationale that it promotes parasympathetic activation and reduces pre-sleep arousal.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Where the evidence comes from

    • Expert opinion

    Why it isn't used for recommendations

    No supporting study on file

    Show studies (1)
    Expert opinion50% confidence

    As a non-pharmacological intervention promoting parasympathetic activation and reducing pre-sleep arousal, it is recommended in integrative protocols for insomnia.

    Open Insomnia
    →
Very low probability(1)
  1. Myopia ProgressionCertaintyVery lowSourceClinicalnot used for recommendations1 cited study

    A randomized controlled trial involving 60 people found that 3 months of yoga therapy did not reduce changes in visual acuity or clinical refraction; only associated symptoms improved.

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Who was studied

    • People with a condition
    • Myopia Progression

    Why it isn't used for recommendations

    Studied, with no positive result

    Show studies (1)
    RCTCno effectn=6040% confidence2014

    Comparative study on the effect of Saptamrita Lauha and Yoga therapy in myopia.

    No significant reduction in visual acuity or clinical refraction after 3 months of yoga therapy; only associated symptoms improved.

    Low-quality journalOpen-label
    Open Myopia Progression
    →

Studied only as breathwork in general, not tested in alternate nostril breathing (nadi shodhana) yet

These results come from studies of breathwork as a whole. No study of alternate nostril breathing (nadi shodhana) has looked at them yet.

COPD (Chronic Obstructive Pulmonary Disease) (Medium · 19 trials) · Physical Endurance Increase (Medium · 14 trials) · Fatigue Reduction (Medium · 8 trials) · Lung Cancer (High · 8 trials) · Anxiety Disorder (General) (Medium · 7 trials) · Oxygen Utilization Improvement (Medium · 6 trials) · and 13 more

All outcomes on the Breathwork page →

Side effects

3 listed

Highest probability

  1. Fainting (Syncope)CertaintyLowSourceReference knowledge1 other source

    Rare cases of vasovagal fainting have been reported in susceptible people using excessive breath control, particularly when the technique includes breath-holding.

    What the sources found

    0 not observed · 0 unclear · 1 reportedconfidence 60/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Where the evidence comes from

    • Reference knowledge1
    Show studies (1)
    Reference knowledgenegative60% confidence

    Rare cases of vasovagal syncope reported with excessive breath control in susceptible individuals, particularly with breath-holding components.

    Open Fainting (Syncope)
    →
  2. DizzinessCertaintyLowSourceReference knowledge1 other source

    Breathing too deeply or rapidly can lower carbon dioxide and cause transient dizziness. It is not expected with comfortable, unforced breathing; stop if dizziness occurs.

    What the sources found

    0 not observed · 0 unclear · 1 reportedconfidence 55/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Where the evidence comes from

    • Reference knowledge1
    Show studies (1)
    Reference knowledgenegative55% confidence

    Transient dizziness can occur if breathing becomes excessively deep or rapid, due to reduced carbon dioxide. It is not expected with comfortable, unforced breathing; stop if it occurs.

    Open Dizziness
    →
  3. HyperventilationCertaintyLowSourceAnecdotal2 other sources

    Breathing too rapidly or deeply, especially while learning the technique, can cause excessive ventilation and reduced carbon dioxide. People mentioned this effect in 2 of 266 Reddit reports discussing it.

    What the sources found

    0 not observed · 0 unclear · 2 reportedconfidence 37/100

    How big is the effect

    No study gave a number we could compare, so the size is not known.

    Where the evidence comes from

    • Expert opinion1
    • Community reports1
    Show studies (2)
    Expert opinionnegative48% confidence

    Breathing too rapidly or deeply, especially while learning the technique, can cause excessive ventilation and hypocapnia.

    Community reportsnegative25% confidence

    This effect was mentioned in 2 of 266 Reddit reports discussing it.

    Open Hyperventilation
    →

5 more mentioned only by users

Don't do it if

When to skip it or get medical advice first3 listed

Highest probability

  1. Hypotension (Low Blood Pressure)CertaintyLowSourceReference knowledgeTheoretical

    Practices that increase vagal tone may lower blood pressure further in people whose blood pressure is already low, with a risk of dizziness or fainting.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 80/100

    Rationale

    The practice enhances vagal tone and may further lower blood pressure, posing risk of syncope or dizziness in individuals with baseline low BP.

    Open Hypotension (Low Blood Pressure)
    →
  2. Recent StrokeCertaintyLowSourceReference knowledgeTheoretical

    In the acute phase after a stroke, autonomic instability and impaired regulation of blood flow in the brain may make controlled breathing that alters vascular tone increase the risk of low blood pressure or altered cerebral perfusion.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 75/100

    Rationale

    In the acute phase post-stroke, autonomic instability and impaired cerebrovascular autoregulation increase risk of hypotension or altered cerebral perfusion during controlled breathing that modulates vascular tone.

    Open Recent Stroke
    →
  3. PheochromocytomaCertaintyLowSourceTheoretical

    Breath-holding or forced breathing can trigger catecholamine release, which may precipitate a hypertensive crisis in people with pheochromocytoma.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 50/100

    Rationale

    Breath-holding or forced breathing can trigger catecholamine release, precipitating hypertensive crisis in pheochromocytoma.

    Open Pheochromocytoma
    →

Who the trials left out

Some trials of this practice did not take people with these conditions, so the studies say less about them. This is not a warning and does not show harm. Ask a clinician first.13 listed
Left out by one trial each (8)

Also listed for breathwork in general (written by our reviewers)

Precautions from the Breathwork page. They are for breathwork as a whole and may not all fit alternate nostril breathing (nadi shodhana).

Aortic Aneurysm · Epilepsy · Bipolar Mania · Psychosis · Unstable Heart Disease (Unstable Angina / Decompensated Heart Failure)

See them on the Breathwork page →

Interactions

Dangerous combinations

Highest severity first

  1. DecongestantsTheoreticalSerious

    Ephedrine can increase heart rate and blood pressure, while Alternate Nostril Breathing (Nadi Shodhana) can modulate autonomic tone; together, they may produce unpredictable cardiovascular responses, especially in sensitive individuals or with improper technique.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 75/100

    Open Decongestants
    →
  2. SupplementsYohimbineTheoreticalSerious

    Yohimbine can increase norepinephrine release and cause anxiety, hypertension, and tachycardia. Combined with Breathwork that influences autonomic balance, it may provoke sympathetic overactivation despite the practice’s parasympathetic intent.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 70/100

    Open Yohimbine
    →
  3. CaffeineTheoreticalCaution

    The concern is theoretical; consult a healthcare provider before combining Caffeine with Alternate Nostril Breathing (Nadi Shodhana).

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 78/100

    Original article finding: Caffeine may induce sympathetic activation and anxiety. Combining it with alternate-nostril breathing aimed at calming could theoretically trigger paradoxical anxiety or palpitations due to opposing physiological states; however, no adverse events have been documented in alternate-nostril-breathing studies, so this caution is theoretical.

    Open Caffeine
    →

Okay to combine with

Highest probability of useful synergy

  1. PracticesMeditationCertaintyMediumSourceReference knowledgePotentiating

    Alternate Nostril Breathing may prepare the body for Meditation by activating the parasympathetic nervous system, potentially deepening its calming effects.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 70/100

    Open Meditation
    →
  2. PracticesVagus Nerve ExercisesCertaintyMediumSourceReference knowledgePotentiating

    Both practices are described as supporting vagal tone and parasympathetic activation; together, they may complement stress resilience and HRV improvement.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 70/100

    Open Vagus Nerve Exercises
    →
  3. SupplementsMagnesiumCertaintyMediumSourceReference knowledgeComplementary

    Magnesium supports GABA-related signaling and reduces neuronal excitability, which may complement the calming effects of Alternate Nostril Breathing.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 68/100

    Open Magnesium
    →
  4. PracticesResonance Frequency BreathingCertaintyMediumSourceReference knowledgeComplementary

    Resonance Frequency Breathing, around 6 breaths/min, and Alternate Nostril Breathing are described as supporting HRV and autonomic balance. Used sequentially, they may have complementary effects on baroreflex sensitivity and emotional regulation.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 65/100

    Open Resonance Frequency Breathing
    →
  5. SupplementsBeetroot ExtractCertaintyMediumSourceReference knowledgePotentiating

    Beetroot Extract may complement the practice's effects on nitric oxide production and cardiovascular function.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 55/100

    Open Beetroot Extract
    →
  6. SupplementsAshwagandhaCertaintyMediumSourceReference knowledgeAdditive

    Ashwagandha's anxiety-reducing effects may complement the stress-reducing effects of Alternate Nostril Breathing.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 45/100

    Open Ashwagandha
    →
  7. SupplementsL-TheanineCertaintyMediumSourceReference knowledgeAdditive

    L-Theanine promotes relaxation without sedation and may add to the calming effects of Alternate Nostril Breathing.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 45/100

    Open L-Theanine
    →
Medium probability(6)
  1. PracticesYogaCertaintyMediumSourceTheoreticalComplementary

    Alternate Nostril Breathing is a pranayama technique used within Yoga; combining it with postures may support mind-body integration and relaxation.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 50/100

    Open Yoga
    →
  2. PracticesHRV Biofeedback TrainingCertaintyMediumSourceTheoreticalComplementary

    HRV Biofeedback Training can provide real-time pacing and autonomic feedback during Alternate Nostril Breathing, helping users find a comfortable, steady rhythm.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 48/100

    Open HRV Biofeedback Training
    →
  3. PracticesProgressive Muscle RelaxationCertaintyMediumSourceTheoreticalAdditive

    Progressive Muscle Relaxation may deepen physical relaxation, complementing the calming mental state associated with Alternate Nostril Breathing.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 45/100

    Open Progressive Muscle Relaxation
    →
  4. PracticesTai ChiCertaintyMediumSourceTheoreticalComplementary

    Tai Chi's slow movements and focus on breath may complement the balancing effects of Alternate Nostril Breathing and support parasympathetic activation.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 45/100

    Open Tai Chi
    →
  5. SupplementsGABACertaintyMediumSourceTheoreticalAdditive

    GABA is the primary inhibitory neurotransmitter; supplementation may add to the calming and parasympathetic effects of Alternate Nostril Breathing.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 40/100

    Open GABA
    →
  6. SupplementsPhosphatidylserineCertaintyMediumSourceTheoreticalPotentiating

    Phosphatidylserine may complement the practice's stress-reducing effects by helping modulate cortisol and supporting adrenal health.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 40/100

    Open Phosphatidylserine
    →

Weakens or is weakened by

Highest probability

  1. PracticesHigh-Intensity Interval Training (HIIT)CertaintyMediumSourceReference knowledgeCompetitive

    High-Intensity Interval Training (HIIT) creates strong sympathetic activity; doing it immediately before or after Alternate Nostril Breathing may create competing autonomic demands and reduce the effectiveness of both.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 62/100

    Open High-Intensity Interval Training (HIIT)
    →
  2. SupplementsAdrafinilCertaintyMediumSourceReference knowledgeCompetitive

    Adrafinil promotes wakefulness and alertness, which may interfere with the relaxation and calming effects of Alternate Nostril Breathing.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 55/100

    Open Adrafinil
    →
  3. SupplementsSynephrine (Bitter Orange)CertaintyMediumSourceReference knowledgeCompetitive

    Synephrine can increase sympathetic activity, opposing the parasympathetic activation associated with Alternate Nostril Breathing.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 55/100

    Open Synephrine (Bitter Orange)
    →
  4. SupplementsCaffeineCertaintyMediumSourceReference knowledgeCompetitive

    Caffeine's stimulant effects may counter the relaxation response from Alternate Nostril Breathing.

    Where the evidence comes from

    • Reference knowledge

    Confidence

    confidence 50/100

    Also listed as a dangerous interaction (caution) — take care when combining; the dangerous entry names the risk. This entry explains how it reduces the practice's benefit.

    Open Caffeine
    →
  5. PracticesBhastrika PranayamaCertaintyMediumSourceTheoreticalCompetitive

    Bhastrika Pranayama uses forceful, rapid breathing that can produce acute arousal, contrasting with the typically slow, calming pattern of Alternate Nostril Breathing.

    Where the evidence comes from

    • Expert opinion

    Confidence

    confidence 42/100

    Open Bhastrika Pranayama
    →

How it works

The mechanisms this practice works through25 listed · 0 established
  • Parasympathetic activityAutonomic nervous systemproposed

    AVP is a slow pranayama practice known to improve parasympathetic activity and sympathovagal balance, cooling the exaggerated sympathetic response.

    PMID 18700626PMID 25364195PMID 33074110

  • Parasympathetic dominanceAutonomic nervous systemproposed

    Slow pranayama breathing activates slowly adapting stretch receptors (SARs) and generates inhibitory impulses and hyperpolarisation currents, leading to increased parasympathetic activity and reduced sympathetic tone.

    PMID 34234391PMID 40242728PMID 41245337

  • Sympathovagal balanceAutonomic nervous systemproposed

    Both pranayama practices reduced LF/HF ratio and increased RMSSD and HF, indicating a shift towards parasympathetic dominance and reduced sympathetic arousal.

    PMID 34213471PMID 37499590

  • Adrenal medullaSympathetic adrenomedullary activationproposed

    The authors suggest the increase in metabolism could be due to increased sympathetic discharge to the adrenal medulla. This is proposed by the authors and was not directly measured in the abstract.

    PMID 8063359

  • Airway resistanceRespiratory muscle efficiencyproposed

    ANB may decrease elastic and viscous resistance of the lungs, increase compliance by releasing surfactant and prostaglandins, and reduce constrictor tone of respiratory smooth muscles, improving PEFR.

    PMID 34234391

  • Amygdala reactivity and prefrontal-amygdala couplingEmotional regulationproposed

    The paper suggests SMK may reduce amygdala hyperreactivity and enhance prefrontal-amygdala coupling, supporting emotional regulation, based on related research on mindfulness meditation and OM chanting.

    PMID 41245337

  • Aqueous outflow at trabecular meshworkNitric oxide pathwayproposed

    Meditation, yoga and Pranayama have been shown to have an effect on nitric oxide in the body, which has an IOP lowering effect by increasing the outflow of aqueous at the trabecular meshwork.

    PMID 36532821

  • Ascending reticular activating system and primary thalamo-cortical levelCentral nervous systemproposed

    Right nostril initiated pranayamas may increase arousal and speed of information processing, while left nostril initiated pranayamas may delay reactivity, as evidenced by changes in reaction time.

    PMID 25035609

  • Cardiac autonomic regulation (SDNN, RMSSD, LF/HF)Neurovisceral integration (autonomic-affective)proposed

    Acute HRV indices did not change significantly by condition; the authors interpret the affective-autonomic dissociation within the NVIM framework without establishing mechanisms.

    PMID 42771122

  • Contralateral (right) hemisphere functionContralateral hemisphere activationproposed

    Authors propose that selective nostril breathing enhances contralateral hemisphere function, which may account for the improved letter-cancellation performance. This was not directly measured.

    PMID 17879663

  • Heart rate variabilityBaroreflex sensitivityproposed

    Breathing exercises significantly increase heart rate variability in pre-hypertensive and hypertensive populations due to increased baroreflex sensitivity, slowing heart rate.

    PMID 38179185

  • Heart rate variability (parasympathetic activity)Autonomic nervous systemproposed

    Alternate nostril breathing was associated with increased beat-to-beat variability of heart rate (SDHR) relative to normal breathing. The authors interpret HRV increases as markers of enhanced parasympathetic activity.

    PMID 31166123

  • Intraocular pressureAutonomic nervous system regulationproposed

    The authors suggest that right nostril breathing has sympathomimetic properties and left nostril breathing has parasympathetic dominance, and both sympathetic and parasympathetic drugs are known to reduce IOP. By stimulating either pathway, pranayama techniques may potentially lower IOP.

    PMID 36532821

  • Parasympathetic activityAutonomic nervous system modulationproposed

    Slow breathing activates pulmonary stretch receptors, increasing inhibitory neural impulses (Hering-Breuer reflex), leading to parasympathetic tone and vasodilation, reducing peripheral resistance and BP.

    PMID 39959506

  • Parasympathetic/sympathetic balanceAutonomic nervous systemproposed

    ANYB is believed to bring about a balance between sympathetic and parasympathetic nervous systems, possibly related to better parasympathetic control over the cardiovascular system, thereby reducing blood pressure.

    PMID 23334063

  • Perceptual sensitivity and focused attentionCortical functionproposed

    ANYB may improve performance in tasks requiring perceptual sensitivity and focused attention, possibly through changes in EEG and improved P300 event-related potential performance.

    PMID 31006767

  • Sympathetic and parasympathetic balanceAutonomic nervous systemproposed

    Right nostril initiated pranayamas induce sympathetic activation, while left nostril initiated pranayamas induce parasympathetic dominance, as evidenced by changes in heart rate and blood pressure.

    PMID 25035609

  • Sympathetic nervous system activityAutonomic nervous system modulationproposed

    Slow and deep breathing exercises inhibit sympathetic nervous system activity and activate cardiopulmonary mechanoreceptors, leading to arteriolar dilatation and decreased blood pressure.

    PMID 38179185

  • Sympathetic nervous system activityAutonomic nervous systemproposed

    Slow yoga breathing at 6 bpm significantly increases sympathetic nervous system activity, as indicated by increased LF power and LF/HF ratio and decreased HF power.

    PMID 36186291

  • VasodilationPulmonary stretch receptorsproposed

    Stimulation of pulmonary stretch receptors during lung inflation may withdraw sympathetic tone in skeletal muscle blood vessels, increasing vasodilation and decreasing diastolic blood pressure.

    PMID 34234391

  • Working memory performanceCognitive functionproposed

    Slow yoga breathing improves reaction time and accuracy in working memory tasks, particularly in the 2-back condition.

    PMID 36186291

  • diaphragm and accessory musclesrespiratory muscle functionproposed

    Breathing exercises may encourage more effective use of the diaphragm, improve breathing coordination, and reduce overreliance on accessory muscles, supporting stronger and more efficient ventilation.

    PMID 41664788

  • mindfulnesspsychologicalproposed

    Yoga practice significantly improved dispositional mindfulness as measured by MAAS

    PMID 40625500

  • psychological flexibilitypsychologicalproposed

    Yoga practice significantly improved psychological flexibility as measured by AAQ

    PMID 40625500

  • stress reductionpsychologicalproposed

    Yoga practice significantly reduced perceived stress levels in athletes

    PMID 40625500

Variations

5 documented

Typical protocol

50 protocolsEstimated

Across every study of this practice, whatever the variation.

15 min · 7×/week

Course
5 weeks
Per week
105 min
Rounds
1–27
Intensity
Low
Format
Individual
Supervision
Instructor-led

Courses and single sessions · 29 repeated-course and 21 single-session protocols

96% of the corpus contributed

Alternate Nostril Breathing with Retention

Intermediate9/1015–30 min · Daily

15–30 min · Daily

Editorial
How often
Daily
Intensity
Low
Time of day
Morning
Where
Indoors
Research depth
Moderate

This variation adds a breath hold after each inhalation; example rhythms include 4:4:8 or 6:6:6 seconds. The instructions say to keep the hold unstrained and reduce the count or skip it if it feels uncomfortable.

No equipment needed.

As studied

14 protocolsEstimated

The protocol the studies of this variation actually used.

15–30 min

Course
6 weeks
Rounds
1
Intensity
Low
Format
Individual
Supervision
Instructor-led

Courses and single sessions · 9 repeated-course and 5 single-session protocols

Derived from1657940318700626286013552915917631006767+9 more in Sources

How it's done7 steps · 3 cues · 3 common mistakes

A general description of the practice, not instruction or medical advice.

Steps

  1. Sit in a comfortable, upright position with your eyes closed.
  2. Adopt Vishnu mudra with your right hand: fold index and middle fingers, use thumb for right nostril, ring finger for left nostril.
  3. Close your right nostril with your thumb. Inhale slowly through the left nostril for a count of 4 (or 6).
  4. Close both nostrils gently and hold the breath for the same count (4 or 6).
  5. Release the right nostril and exhale slowly through it for double the count (8 or 12).
  6. Inhale through the right nostril for the same count, hold with both nostrils closed, then exhale through the left nostril for double the count. This completes one cycle.
  7. Repeat for 10-30 minutes, maintaining the ratio and a steady rhythm.

Cues

  • · Keep the breath smooth and silent; avoid straining during the hold.
  • · If the hold feels uncomfortable, reduce the count or skip the retention.
  • · Maintain a slight chin lock (Jalandhara Bandha) if comfortable, to prevent pressure in the head.

Common mistakes

  • Holding the breath too long, causing tension or dizziness.
  • Inhaling or exhaling too forcefully.
  • Losing the count and becoming irregular.
Studied protocols14 on file
  • 30 min· 5×/week· 4 weeks· n=27· A repeated coursePMID 28601355
  • 15 min· 14×/week· 1 week· n=60· A repeated coursePMID 33074110
  • 15 min· 5×/week· 6 weeks· n=100· A repeated coursePMID 37693083
  • 21 min· 7×/week· 6 weeks· n=24· A repeated coursePMID 41245337
  • 15 min· 7×/week· 8 weeks· Rounds 1· n=40· A repeated coursePMID 16579403
  • 15 min· 7×/week· 4 weeks· A repeated coursePMID 18700626

Showing 6 of 14 — the rest are in Sources

Basic Alternate Nostril Breathing

Beginner8/105–10 min · Daily

5–10 min · Daily

Editorial
How often
Daily
Intensity
Low
Time of day
Morning
Where
Indoors or outdoors
Research depth
Minimal

This version usually alternates nostrils without holding the breath, using a gentle, natural pace. The described routine lasts 5-10 minutes and emphasizes keeping the shoulders relaxed and the breath unforced.

No equipment needed.

As studied

15 protocolsEstimated

The protocol the studies of this variation actually used.

5–10 min

Course
5 weeks
Rounds
27
Intensity
Low
Format
Individual
Supervision
Instructor-led

Courses and single sessions · 8 repeated-course and 7 single-session protocols

Derived from2333406323814719268940622886218331180234+10 more in Sources

How it's done7 steps · 3 cues · 3 common mistakes

A general description of the practice, not instruction or medical advice.

Steps

  1. Sit comfortably with your spine erect, either on a chair or cross-legged on the floor.
  2. Rest your left hand on your left knee, palm facing up or in a comfortable position.
  3. Bring your right hand to your nose. Curl your index and middle fingers toward your palm, leaving the thumb, ring finger, and little finger extended (Vishnu mudra).
  4. Close your right nostril with your right thumb. Inhale slowly and deeply through your left nostril.
  5. Close your left nostril with your ring finger, release your thumb from the right nostril, and exhale slowly through the right nostril.
  6. Inhale through the right nostril, then close it with your thumb, release the left nostril, and exhale through the left nostril. This completes one cycle.
  7. Continue alternating for 5-10 minutes, keeping the breath smooth and effortless.

Cues

  • · Keep your shoulders relaxed and your face soft.
  • · Maintain a gentle, natural pace; do not force the breath.
  • · Focus on the sensation of air passing through each nostril.

Common mistakes

  • Using too much force to close the nostrils, causing tension.
  • Breathing too quickly or shallowly.
  • Slouching or collapsing the chest.
Studied protocols27 on file
  • 10 min· 14×/week· 0.7 weeks· n=170· A repeated coursePMID 31463330
  • 10 min· 6×/week· 8 weeks· n=135· A repeated coursePMID 39360069
  • 10 min· 7×/week· 4 weeks· n=100· A repeated coursePMID 32320171
  • 10 min· 7×/week· 4 weeks· n=100· A repeated coursePMID 34213471
  • 10 min· 1×/week· 7 weeks· n=140· A repeated coursePMID 34659061
  • 5 min· 6 weeks· A repeated coursePMID 23814719

Showing 6 of 27 — the rest are in Sources

Extended Alternate Nostril Breathing

Intermediate8/1020–30 min · Daily

20–30 min · Daily

Editorial
How often
Daily
Intensity
Low
Time of day
Morning
Where
Indoors
Research depth
Minimal

This longer format lasts 20-30 minutes and combines alternating nostril breathing with deep abdominal breathing; gentle breath holds may be added. The instructions suggest dropping the holds if fatigue arises and sitting quietly for a minute at the end.

No equipment needed.

How it's done6 steps · 3 cues · 3 common mistakes

A general description of the practice, not instruction or medical advice.

Steps

  1. Begin by sitting comfortably with your spine erect. Take a few deep abdominal breaths to prepare.
  2. Adopt Vishnu mudra. Start with a few rounds of basic alternate nostril breathing without retention to warm up.
  3. Gradually introduce a gentle breath hold after each inhalation, using a ratio that feels comfortable (e.g., 4:4:8).
  4. Continue the practice, maintaining a steady rhythm and focusing on the smooth transition between nostrils.
  5. If you feel fatigued, you may drop the retention and continue with simple alternating breaths.
  6. After 20-30 minutes, release the mudra, sit quietly with your eyes closed for a minute, and observe the effects.

Cues

  • · Keep your breath deep and diaphragmatic throughout.
  • · Maintain a slight smile to keep the face relaxed.
  • · If your arm tires, you can switch hands or support your elbow with a cushion.

Common mistakes

  • Pushing through discomfort or breathlessness.
  • Allowing the mind to wander without returning to the breath.
  • Ending the practice abruptly without a moment of stillness.
Studied protocols1 on file
  • 12 min· 7×/week· 6 weeks· n=68· A repeated coursePMID 40242728

Slow-Paced Alternate Nostril Breathing

Intermediate8/1021–30 min · Daily

21–30 min · Daily

Editorial
How often
Daily
Intensity
Low
Time of day
First half of the day
Where
Indoors
Research depth
Minimal

This version guides breathing at about 5-6 breaths per minute, with an example cycle of 4-second breaths and 2-second pauses. The pauses are intended to remain comfortable rather than strained.

No equipment needed.

How it's done7 steps · 3 cues · 3 common mistakes

A general description of the practice, not instruction or medical advice.

Steps

  1. Sit in a steady, comfortable posture with your spine straight.
  2. Set a timer or use a metronome app set to 5 or 6 beats per minute to guide your breath pace.
  3. Use Vishnu mudra. Close your right nostril and inhale through the left nostril for 4 seconds.
  4. Close both nostrils and pause for 2 seconds.
  5. Exhale through the right nostril for 4 seconds, then pause for 2 seconds with both nostrils closed.
  6. Inhale through the right nostril for 4 seconds, pause 2 seconds, exhale left for 4 seconds, pause 2 seconds. This is one cycle.
  7. Continue for 15-30 minutes, keeping the rhythm consistent.

Cues

  • · Let the breath be soft and effortless; the pauses should be comfortable, not strained.
  • · Keep your awareness on the flow of breath and the subtle pauses.
  • · If you lose track, gently restart the cycle without frustration.

Common mistakes

  • Rushing the breath to keep up with the timer.
  • Holding tension in the face or jaw during pauses.
  • Breathing from the chest instead of the diaphragm.
Studied protocols2 on file

Quick Stress Relief Alternate Nostril Breathing

Beginner7/105 min · As needed

5 min · As needed

Editorial
How often
As needed
Intensity
Very low
Time of day
Any time
Where
Indoors or outdoors
Research depth
Minimal

This is a 5-minute version with smooth alternating breaths and no breath retention, intended for a brief reset during the day. Its instructions emphasize keeping the breath gentle and bringing attention back to it when the mind wanders.

No equipment needed.

How it's done6 steps · 3 cues · 3 common mistakes

A general description of the practice, not instruction or medical advice.

Steps

  1. Find a quiet place to sit comfortably, even if just for a few minutes.
  2. Close your eyes and take a few natural breaths to settle in.
  3. Use your right hand in Vishnu mudra. Close your right nostril with your thumb and inhale slowly through the left nostril.
  4. Close the left nostril with your ring finger, release the right nostril, and exhale through the right.
  5. Inhale through the right nostril, then close it, release the left, and exhale through the left.
  6. Continue this alternating pattern for 5 minutes, keeping the breath gentle and unhurried.

Cues

  • · Focus on the sensation of the breath cooling and calming your mind.
  • · If your mind wanders, gently bring it back to the breath.
  • · Keep your facial muscles relaxed.

Common mistakes

  • Breathing too fast or shallowly due to time pressure.
  • Slouching because of a casual setting.
  • Forgetting to alternate nostrils correctly.

How to start

Community experience

Based on 291 public posts from Reddit, Bluesky, Hacker News, and YouTube.

Signal found56 signals4 platforms
Reddit 266Bluesky 12Hacker News 7YouTube 6

What people report it did

21 outcomes mentioned across 291 public reports. A report often mentions several, so these counts do not add up to the total.

Reported side effects5

What people report doing

Counted from public posts and videos, not from a survey. Each figure counts the posts that mentioned it — most reports say nothing about schedule.

How often9 mentions

Daily6As needed3

Intensity3 mentions

Low3

When5 mentions

Morning5

Session lengthas written

“5 minutes”“10 minutes”“5 minutes”“2-3 minutes”“5 minutes”

References

54 screened · 52 analysed · 53 listed below

Studies and sources cited on this page. Evidence quality varies — check the grade on each.

  1. Effect of breathing exercises on blood pressure and heart rate: A systematic review and meta-analysis.Int J Cardiol Cardiovasc Risk Prev2024Meta-analysisBn=1097
  2. Effectiveness of Alternative Nostril Breathing on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Complement Med Res2024Meta-analysisBn=1377
  3. Effect of an Eight-Week Breathing Exercise Program on the Respiratory Function and Craniovertebral Angle in Dental Students: A Pre-test and Post-test Quasi-experimental Study.Cureus2026Quasi ExperimentalCn=40
  4. Short-Term Effects of Nostril-Regulated Yoga Breathing on Autonomic Variables: A Randomized Crossover Trial.Int J Yoga Therap2026Crossover RCTCn=45
  5. Acute Psychophysiological Effects Of 4-7-8 And Nadi Shodhana Breathing: A Randomized Crossover Study.Appl Psychophysiol Biofeedback2026Crossover RCTCn=34
  6. An Investigation of the Effects of Yoga on the Psychological Well-Being of Young Athletes: A Randomized Controlled Trial.Cureus2025RCTCn=88
  7. Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.Int J Yoga2025RCTCn=86
  8. Effects of yogic practices on physiological and biochemical parameters of hypertensive patients: A systematic review of clinical trials.J Ayurveda Integr Med2025Systematic reviewCn=1306
  9. An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.Ann Neurosci2025RCTCn=68
  10. The impact of alternate nostril breathing on the severity and frequency of migraine attacks: a randomized control trial.Prim Health Care Res Dev2025RCTCn=86
Show all 53 references
  1. The effect of breathing exercises on pain, sleep, and symptom management in patients undergoing hemodialysis: a randomized controlled trial.2025RCTCn=69
  2. Immediate Hemodynamic Changes during Slow Uninostril and Alternate Nostril Breathing Patterns in Normotensive Adults.2024RCTCn=132
  3. The Impact of Yogic Breathing Exercises on Pulmonary Functions in Asymptomatic Smokers.2024Quasi ExperimentalCn=135
  4. Effects of an 8-week intervention of anulom vilom pranayama combined with heartfulness meditation on psychological stress, autonomic function, inflammatory biomarkers, and oxidative stress in healthcare workers during COVID-19 pandemic: a randomized controlled trial.2024RCTCn=100
  5. Effects of Nadishodhana and Bhramari Pranayama on heart rate variability, auditory reaction time, and blood pressure: A randomized clinical trial in hypertensive patients.2023RCTCn=100
  6. Effect of alternate nostril breathing exercise on autonomic functions, ocular hypertension, and quality of life in elderly with systemic hypertension and high-tension primary open-angle glaucoma.2023RCTCn=60
  7. Effect of alternate nostril breathing on evoked potentials among internet addicts.2022Quasi ExperimentalCn=100
  8. Slow yoga breathing improves mental load in working memory performance and cardiac activity among yoga practitioners.2022Crossover RCTCn=40
  9. The Effect of Specific Techniques of Nasal Breathing [Pranayama] on Intra-Ocular Pressure in Normal Individuals, a Randomized Trial.2022RCTCn=164
  10. The Effect of Pranayamic Breathing as a Positive Psychology Exercise on Foreign Language Learning Anxiety and Test Anxiety Among Language Learners at Tertiary Level.2021Quasi ExperimentalCn=140
  11. Effect of alternate nostril breathing on cardio respiratory parameters and muscle strength among rotating shift workers.2021Observational Cross SectionalCn=280
  12. Effects of alternate nostril breathing exercise on cardiorespiratory functions in healthy young adults.2021RCTCn=100
  13. Can Breathing Exercise or Pranayama Affect the Intraocular Pressure in the Short-term?2021Observational Cross SectionalCn=73
  14. Effects of alternate nostril breathing exercise on respiratory functions in healthy young adults leading stressful lifestyle.2020Quasi ExperimentalCn=100
  15. Effects of alternate nostril breathing exercise on cardiac functions in healthy young adults leading a stressful lifestyle.2020RCTCn=100
  16. Breathing exercises and pranayamas to decrease perceived exertion during breath-holding while locked-down due to COVID-19 online randomized study.2020RCTCn=60
  17. Changes in Shape and Size Discrimination and State Anxiety After Alternate-Nostril Yoga Breathing and Breath Awareness in One Session Each.2019Crossover RCTCn=50
  18. Effect of alternate nostril breathing exercise on blood pressure, heart rate, and rate pressure product among patients with hypertension in JIPMER, Puducherry.2019RCTCn=170
  19. The impact of deep breathing and alternate nostril breathing on heart rate variability: a human physiology laboratory.2019Quasi ExperimentalCn=55
  20. A Pilot Study on the Effect of Alternate Nostril Breathing and Foot Reflexology on Intraocular Pressure in Ocular Hypertension.2019Pilot studyCn=11
  21. Effect of Alternate Nostril Breathing Exercise on Experimentally Induced Anxiety in Healthy Volunteers Using the Simulated Public Speaking Model: A Randomized Controlled Pilot Study.2017RCTCn=30
  22. Acute effects on cardiovascular oscillations during controlled slow yogic breathing.2017Quasi ExperimentalCn=12
  23. Yogic breathing practices improve lung functions of competitive young swimmers.2017RCTCn=27
  24. Deep Breathing Practice Facilitates Retention of Newly Learned Motor Skills.2016RCTCn=40
  25. Effect of Left, Right and Alternate Nostril Breathing on Verbal and Spatial Memory.2016Quasi ExperimentalCn=51
  26. Alternate Nostril Breathing at Different Rates and its Influence on Heart Rate Variability in Non Practitioners of Yoga.2016Quasi ExperimentalCn=25
  27. Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness.2014Quasi ExperimentalCn=41
  28. Comparative study on the effect of Saptamrita Lauha and Yoga therapy in myopia.2014RCTCn=60
  29. Differential effects of uninostril and alternate nostril pranayamas on cardiovascular parameters and reaction time.2014Quasi ExperimentalCn=20
  30. Assessment of the effects of pranayama/alternate nostril breathing on the parasympathetic nervous system in young adults.2013Quasi ExperimentalC
  31. Blood pressure and Purdue pegboard scores in individuals with hypertension after alternate nostril breathing, breath awareness, and no intervention.2013RCTCn=90
  32. Effect of short-term practice of pranayamic breathing exercises on cognition, anxiety, general well being and heart rate variability.2013RCTCn=96
  33. Influence of alternate nostril breathing on heart rate variability in non-practitioners of yogic breathing.2012Crossover RCTCn=20
  34. Effect of alternate nostril breathing exercise on cardiorespiratory functions.2008Quasi ExperimentalC
  35. Immediate effect of three yoga breathing techniques on performance on a letter-cancellation task.2007RCTCn=20
  36. Influence of alternate nostril breathing on cardiorespiratory and autonomic functions in healthy young adults.2005Quasi ExperimentalCn=40
  37. Yoga breathing through a particular nostril increases spatial memory scores without lateralized effects.1997RCTCn=135
  38. Pranayama increases grip strength without lateralized effects.1997RCTCn=130
  39. EEG changes during forced alternate nostril breathing.1994Quasi ExperimentalCn=18
  40. Breathing through a particular nostril can alter metabolism and autonomic activities.1994RCTCn=48
  41. A study of yoga as a nursing intervention in the care of patients with pleural effusion.1984Quasi ExperimentalCn=20
  42. The effect of the inner engineering program on interpersonal relationships: a qualitative study of emotional regulation and relational transformation.2025QualitativeDn=24
  43. Expert knowledge synthesis

Diatelos provides general wellness information based on published research. It is not medical advice. Talk to a clinician before starting any new supplement or practice, especially if you have a health condition, are pregnant, or take medication.