minerals
Transferrin Saturation
Transferrin Saturation is a biomarker listed within the minerals category and expressed as a percentage.
- Short name
- TSAT
- Unit
- %
- Reference min
- 20
- Reference max
- 50
- Optimal min
- 25
- Optimal max
- 40
- Better when
- in range
- Reference min (male)
- 20
- Reference max (male)
- 50
- Reference min (female)
- 20
- Reference max (female)
- 50
- Sample
- serum
- Fasting required
- true
- Related markers
- Serum Iron, Total Iron Binding Capacity, Ferritin
Moved by
Interventions that trials measured against this marker, and which way it moved.No trial has measured Transferrin Saturation against an intervention in this library yet.
Full write-up
What is it
Transferrin Saturation, abbreviated TSAT, is a biomarker categorized with minerals. It is expressed as a percentage, making it a percentage-based marker rather than a measurement reported in a mass unit. Its role here is to provide a mineral-related biomarker value for reference.
How to test it
Transferrin Saturation is measured using a serum sample, typically collected through a blood test. Fasting is required for this measurement, so the collection should be arranged under fasting conditions. The laboratory or clinician arranging the test can provide the specific instructions for preparing and attending the appointment.
The result is reported as a percentage. Interpretation uses the reference and optimal ranges shown with the result, rather than relying on the percentage alone. The applicable range may also be presented by sex, with the male and female ranges shown for comparison.
Transferrin Saturation may be reviewed alongside Iron Serum, Tibc, and Ferritin. Considering these related markers together can provide context when a clinician is assessing an iron-related picture, rather than treating Transferrin Saturation as an isolated finding. Any result that raises questions should be discussed with a qualified clinician, particularly when testing is being performed for a medical condition.
Reading your result
Transferrin Saturation is interpreted as a percentage from a serum sample. The reference range is the broader interval used for interpretation, while the optimal range is tighter and represents the preferred part of that interval. The ranges shown are the same for males and females.
Fasting is required for this measurement, so the result should be considered alongside the conditions under which the sample was collected. A single value is not a diagnosis. If a result falls outside the reference range printed on the report, discuss it with a clinician, particularly in the context of any medical condition.
What moves it
Direct evidence for changing transferrin saturation involves Iron, with trials measuring this exact marker and finding movement upward. The findings were not completely uniform across studies, so an increase should be understood as an observed pattern rather than a guaranteed response for every person.
The research assessed transferrin saturation over a follow-up period of about 24.0 weeks. Because this marker is represented by a range in which values are considered optimal, movement upward is not automatically the desired direction in every context; interpretation depends on where the starting and resulting values sit relative to that range.
These findings describe how Iron has affected transferrin saturation in studied settings, not a general instruction to use it. Anyone considering changes related to a medical condition should review the result and its context with a clinician.