Antiplatelet Agents
A reference for questions about taking other medicines or supplements with Antiplatelet Agents. Review relevant interaction information before combining products.
2 supplements in this library have a recorded interaction with this medication
Dangerous combinations
Supplements recorded as risky with this medication2 listedHighest severity first
- →SupplementsChagaTheoreticalCaution
Chaga inhibits platelet aggregation, so combining it with antiplatelet agents may increase bleeding risk.
- →SupplementsSea Moss (Irish Moss)TheoreticalCaution
Clinically relevant antiplatelet activity from oral sea moss is not established; any additive effect with antiplatelet drugs is theoretical.
Where the evidence comes from
- Reference knowledge
Open Sea Moss (Irish Moss)Confidence
confidence 60/100
- Trade names
- Aspirin (Low-Dose), Clopidogrel (Plavix), Ticagrelor (Brilinta), Prasugrel (Effient), Dipyridamole (Persantine)
- family
- antiplatelet agents
Full write-up
What is it
Antiplatelet Agents are blood-related medicines in the antiplatelet agent family. This group includes Aspirin (Low-Dose), Clopidogrel (Plavix), Ticagrelor (Brilinta), Prasugrel (Effient), and Dipyridamole (Persantine). They are generally used in medical care where antiplatelet treatment is relevant.
This page is an educational reference for checking whether other medicines or supplements may interact with Antiplatelet Agents. Anyone with a medical condition should consult a clinician when considering combinations with other products.
What interacts with it
The clearest concern is additive inhibition of platelet function, which can increase bleeding risk when antiplatelet agents are combined with Black Seed Oil, Curcumin, Resveratrol, or Vitamin E. This concern is particularly relevant with aspirin, clopidogrel, or ticagrelor, because the supplement and medication may both reduce platelet aggregation.
A broader group has possible or pharmacologically plausible effects on platelet function. This includes American Ginseng, Aloe Vera, Astaxanthin, Astragalus, Bacopa Monnieri, Berberine, Chaga, Chamomile, Chondroitin Sulfate, Cod Liver Oil, Cordyceps, Evening Primrose Oil, Flaxseed Oil, Ginger, Green Tea Extract (EGCG), and Horny Goat Weed (Epimedium). Combining these with antiplatelet agents may contribute to bruising or bleeding through additive effects, although the strength of evidence varies between supplements. For Astragalus, the concern is based on preclinical models, while human interaction data are limited for some of these combinations.
Some reported interactions are theoretical rather than established. A bleeding interaction has not been demonstrated in humans for Acetyl-L-Carnitine (ALCAR), and no clinically meaningful bleeding interaction has been established for Collagen or Coenzyme Q10. Chlorella and Cranberry Extract also have uncertain or theoretical concerns rather than established clinical effects on platelet function. Routine awareness of bruising or bleeding may be relevant for these combinations, but the evidence is weaker.
Anyone taking an antiplatelet agent and considering one of these supplements can discuss the combination with a prescriber or pharmacist, particularly when there is already an elevated bleeding risk. No useful combination is established in these interaction references.