History of Anaphylaxis
History of Anaphylaxis refers to a prior episode of anaphylaxis, a severe allergic reaction. It is used as a condition label in reference materials to indicate that this history may be relevant when considering certain products or exposures.
A history of anaphylaxis is an important immune-related medical history item. This page gives a simple overview of what the term means.
This list shows research findings, not treatments. Nothing here replaces medical care. If you have this condition, talk to a doctor.
May not suit people with this condition
Supplements and practices linked to problems for people with this condition.
Gardening TherapypracticeUnclear
During outdoor Gardening Therapy, insect stings or plant allergens may trigger anaphylaxis in people with a history of anaphylaxis.
Open the Gardening Therapy page
The expert view shows every study, dose protocol and source.
What may help
Interventions recorded as helping with this conditionNothing in this library is currently recorded as helping with History of Anaphylaxis. That means nothing is on file — not that nothing exists. Only 107 of 338 catalogued supplements have a written-up profile so far.
What to avoid
Interventions recorded as making it worse1 listedHighest probability
- →PracticesGardening TherapyCertaintyLowSourceReference knowledge
During outdoor Gardening Therapy, insect stings or plant allergens may trigger anaphylaxis in people with a history of anaphylaxis.
Open Gardening TherapyRationale
Risk of insect stings or plant allergens triggering anaphylaxis during outdoor gardening.
How to read the evidence
Evidence tier — overall strength of the evidence for the whole compound
- StrongWell established — backed by strong, consistent human research.
- ModerateSome genuine support, but mostly from small or lower-quality studies. Promising, not proven.
- PreliminaryEarly-stage evidence — a promising hypothesis, not an established effect yet.
- LimitedVery limited evidence — treat this as a hypothesis, not proof.
- InsufficientNot enough good evidence to draw conclusions yet.
Certainty — how sure we can be that the effect is real
- Very highVery sure — strong, consistent evidence
- HighFairly sure — consistent evidence from good studies
- MediumModerately sure — new studies could change this
- LowNot sure — little or mixed evidence
- Very lowVery unsure — almost no usable evidence
Source — where the data comes from
- Meta-analysisPooled analysis of many trials — the strongest evidence
- RCTRandomized controlled trial — a strong human study design
- ClinicalA human clinical study
- Reference knowledgeFrom general health-science or pharmacology references, not a study of this exact claim
- Animal researchStudied in animals, not humans
- Community reportsAggregated user reports — anecdotal signal, not evidence
- TheoreticalMechanism-based reasoning, not yet tested
Study grade — quality of each underlying study (A best, D weakest)
- AHigh-quality — strong, consistent human trials
- BGood — solid evidence with some limitations
- CModerate — limited, small, or mixed-quality studies
- DWeak — preliminary, indirect, or animal-only
Confidence — how strongly the sources back a finding
A 0–100 score from study quality and agreement
Most supplement evidence is graded C–D. Read it as preliminary signal, not proof.
Full write-up
What is it
History of Anaphylaxis refers to a prior episode of anaphylaxis, a severe allergic reaction. It is used as a condition label in reference materials to indicate that this history may be relevant when considering certain products or exposures.
The grounding data does not provide details about symptoms, causes, or management, so this entry is intentionally brief. For any personal medical questions about a history of anaphylaxis, a clinician can help interpret what it means in context.
Evidence-backed options
No evidence-backed options are listed for History of Anaphylaxis in the provided data. That means this section cannot identify supplements or other products with supported benefit for this condition based on the available evidence.
For a condition history like this, the most useful next step is usually a clinician review of the person’s allergy history and any prior reactions, especially before considering products that may be relevant to allergies or immune responses. Because the grounded data here does not include any supported options, no specific supplement can be recommended from this page.
What to avoid
For a history of anaphylaxis, the main things to avoid are products that are listed here as avoid, especially those with high probability. That includes Amylase, Bee Pollen, Bee Propolis, Black Cohosh, Cellulase, Echinacea, Lactase, N-Acetylcysteine (NAC), Papain, Propranolol, Casein Protein, Egg Protein, Royal Jelly, and Trypsin.
Bromelain is also listed as avoid, with medium probability, while Lipase is listed as avoid with very low probability. In practice, this means the level of concern is not the same for every item, but all of them are included in the avoid-with group for this condition.
Because anaphylaxis can be a serious medical condition, any review of supplements or medications should be done with a clinician who can consider the full history and current exposures.