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Hormonal

Amenorrhea

Amenorrhea is a condition in which menstrual periods are absent. It is categorized here as a hormonal condition, which means it can be related to changes in the body’s hormone balance.

Amenorrhea is a hormonal condition. This page gives a simple overview and notes its relation to Vitex Agnus-Castus.

This list shows research findings, not treatments. Nothing here replaces medical care. If you have this condition, talk to a doctor.

What may help

None of these options has good evidence yet. Best evidence first.

1 option:1 not enough evidence

  • YogapracticeNot enough evidence

    Too few or too small studies to know if it works.

    The one study found a benefit.

    A review of 7 randomized trials reported improvements among women with menstrual disorders, but the abstract did not give effect sizes.

    Open the Yoga page

The expert view shows every study, dose protocol and source.

What may help

Interventions recorded as helping with this condition1 listed

The best we have, but the evidence is still weak

  1. PracticesYogaCertaintyLowSourceClinical

    A review of 7 randomized trials reported improvements among women with menstrual disorders, but the abstract did not give effect sizes.

    Who was studied

    • People with a condition
    • Amenorrhea
    • Dysmenorrhea
    • Pms

    Study result

    Review of seven RCTs reporting improvements in women with menstrual disorders; effect sizes not given in abstract.

    Open Yoga
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What to avoid

Interventions recorded as making it worse

Nothing in this library is currently recorded as making Amenorrhea worse. Coverage is partial, and absence here is not evidence of safety.

Browse the supplements that are written up

How to read the evidence

Evidence tier — overall strength of the evidence for the whole compound

  • StrongWell established — backed by strong, consistent human research.
  • ModerateSome genuine support, but mostly from small or lower-quality studies. Promising, not proven.
  • PreliminaryEarly-stage evidence — a promising hypothesis, not an established effect yet.
  • LimitedVery limited evidence — treat this as a hypothesis, not proof.
  • InsufficientNot enough good evidence to draw conclusions yet.

Certainty — how sure we can be that the effect is real

  • Very highVery sure — strong, consistent evidence
  • HighFairly sure — consistent evidence from good studies
  • MediumModerately sure — new studies could change this
  • LowNot sure — little or mixed evidence
  • Very lowVery unsure — almost no usable evidence

Source — where the data comes from

  • Meta-analysisPooled analysis of many trials — the strongest evidence
  • RCTRandomized controlled trial — a strong human study design
  • ClinicalA human clinical study
  • Reference knowledgeFrom general health-science or pharmacology references, not a study of this exact claim
  • Animal researchStudied in animals, not humans
  • Community reportsAggregated user reports — anecdotal signal, not evidence
  • TheoreticalMechanism-based reasoning, not yet tested

Study grade — quality of each underlying study (A best, D weakest)

  • AHigh-quality — strong, consistent human trials
  • BGood — solid evidence with some limitations
  • CModerate — limited, small, or mixed-quality studies
  • DWeak — preliminary, indirect, or animal-only

Confidence — how strongly the sources back a finding

A 0–100 score from study quality and agreement

Most supplement evidence is graded C–D. Read it as preliminary signal, not proof.

Full write-up

What is it

Amenorrhea is a condition in which menstrual periods are absent. It is categorized here as a hormonal condition, which means it can be related to changes in the body’s hormone balance.

This page includes two entities that may be discussed in connection with amenorrhea: Vitex Agnus-Castus and Clomiphene. For any case of absent periods, a clinician can help determine the cause and whether it needs evaluation.

Evidence-backed options

For amenorrhea, the available evidence-backed options in this data are limited. Clomiphene and Vitex Agnus-Castus are both listed as helping, but the evidence level is very low and comes from a pharmacology reference rather than stronger clinical evidence. That means they appear in reference materials as possible options, but the support for their use is not robust.

Because amenorrhea can have different causes, the most relevant option depends on why periods have stopped. This summary does not indicate which option is appropriate for any individual case, and it does not replace evaluation by a clinician.

Diatelos provides general wellness information based on published research. It is not medical advice. Talk to a clinician before starting any new supplement or practice, especially if you have a health condition, are pregnant, or take medication.