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cardiac

Creatine Kinase

Creatine Kinase is a cardiac biomarker used in clinical reference contexts. Explore its role and measurement details in one place.

Short name
CK
Unit
U/L
Reference min
30
Reference max
200
Optimal min
50
Optimal max
150
Better when
in range
Reference min (male)
40
Reference max (male)
200
Reference min (female)
30
Reference max (female)
170
Sample
serum
Fasting required
false

Moved by

Interventions that trials measured against this marker, and which way it moved.

No trial has measured Creatine Kinase against an intervention in this library yet.

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Full write-up

What is it

Creatine Kinase (CK) is a cardiac biomarker used in clinical reference contexts. It is a laboratory marker that contributes to assessment of cardiac-related health information, with results interpreted as part of the broader clinical picture.

How to test it

Creatine Kinase is assessed from a serum sample. Fasting is not required for this test, so the collection does not depend on an overnight fast.

When the result is reviewed, use the reference range that applies to the person being tested. The page also presents sex-specific ranges and a narrower optimal range, so interpretation should follow the appropriate context rather than relying on a single universal cutoff.

Reading your result

Creatine Kinase is reported from a serum sample in U/L, and fasting is not required for this measurement. The report provides a reference range and a tighter optimal range; these are different comparison bands, so a result can be within the broader reference range without falling within the optimal range. Separate male and female ranges are also shown, reflecting that interpretation may use the range relevant to the report.

A laboratory result should be read against the reference range and units printed on that report, rather than interpreted as an isolated number. Ranges can differ between reports, so the accompanying laboratory information is important when comparing results. A single value is not a diagnosis and does not, by itself, establish that something is wrong or explain why a result falls outside a range.

Results outside the reported range belong in discussion with a clinician, particularly when considered alongside symptoms, medical history, or other findings. This page is educational reference content and cannot determine what an individual result means.

What moves it

Creatine Kinase is considered optimal within a range, so a lower value is not automatically better than a value that remains within the appropriate range. The interventions discussed here were measured directly against this marker, rather than inferred from related outcomes.

Lower Creatine Kinase was reported with Rhodiola Rosea, BCAA, Coenzyme Q10, Astaxanthin, Astragalus, Green Tea Extract (EGCG), Vitamin E, Quercetin, and Cordyceps. In contrast, L-Leucine, Vitamin K2, Whey Protein, L-Carnitine, Ginger, and Tribulus Terrestris showed no significant change in the direct measurements described. These findings do not indicate that every study reached the same conclusion: some interventions had mixed results across studies, while others were supported by a single study.

The evidence includes both meta-analyses and randomized controlled trials, so the amount and consistency of support differs between interventions. The typical time to recheck ranged from 0.7 to 16.0 weeks, with some measurements focused on the period after exercise and others occurring after several weeks of use. Creatine Kinase can also vary with the context in which it is measured, so comparisons are most meaningful when timing and testing conditions are considered consistently. For a medical condition or an unexpectedly abnormal result, interpretation is best discussed with a clinician.

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