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Liver

Alanine Aminotransferase

Alanine Aminotransferase is a liver biomarker measured in U/L.

Short name
ALT
Unit
U/L
Reference min
7
Reference max
56
Optimal min
7
Optimal max
30
Better when
lower is better
Reference min (male)
10
Reference max (male)
56
Reference min (female)
7
Reference max (female)
45
Sample
serum
Fasting required
false

Moved by

Interventions that trials measured against this marker, and which way it moved.

No trial has measured Alanine Aminotransferase against an intervention in this library yet.

Browse the supplements that are written up

Via effects

Interventions targeting an effect this marker tracks. Trials did not measure the marker itself.

Full write-up

What is it

Alanine Aminotransferase, or ALT, is a biomarker for the liver. It is measured in U/L, providing a laboratory measurement related to liver health. ALT is a marker, not a description of symptoms.

How to test it

Alanine Aminotransferase testing requires a serum sample and is reported in U/L. Fasting is not required, so the test can be arranged without fasting preparation. The key collection requirement is that the laboratory receives the appropriate serum sample for analysis.

Results are interpreted against the reference range shown for Alanine Aminotransferase, with a separate optimal range and sex-specific ranges also available. These ranges provide context for understanding whether a result falls within a commonly used interval and how it compares with the more favorable range, since lower values are preferred for this marker. The relevant comparison may depend on which reference framework is being used, so interpretation is best discussed with a clinician when the result is part of a broader health assessment.

Reading your result

Interpret Alanine Aminotransferase against the reference range printed on the laboratory report, using the same units. Laboratories may use different ranges and units, so a number is meaningful only in the context of the range reported with it. The applicable range may also vary by sex, as reflected in the report’s ranges.

The optimal range is narrower than the reference range and represents a tighter target for a reading considered more favorable. For Alanine Aminotransferase, lower is better, but a result within the reference range is not, by itself, a diagnosis or a complete assessment of health. A single value should be considered alongside the clinical context and other relevant findings. Results outside the report’s reference range should be discussed with a clinician, particularly when evaluating a medical condition.

What moves it

Alanine Aminotransferase is a marker for which lower values are generally preferred. In trials that measured this marker directly, Milk Thistle (Silymarin), Vitamin E, Omega-3, Berberine, Chlorella, Garlic, Coenzyme Q10, Panax Ginseng, Saffron Extract, Black Seed Oil, Quercetin, Reishi, SAM-e, and Ginger were associated with decreases. Resveratrol had conflicting findings rather than a consistent direction. These results came from interventions evaluated separately, with study rechecks ranging from 5.0 to 26.1 weeks, so the timing of any change was not uniform.

Several interventions overlap with broader entries for Liver Health Support, Fatty Liver Prevention, or Detoxification Support. These target effects that this marker tracks, though trials did not measure Alanine Aminotransferase directly for this group. The related-effect entries include Vitamin E, Berberine, Ginger, Black Seed Oil, Garlic, Alpha-Lipoic Acid (ALA), Cycling, Milk Thistle (Silymarin), Coenzyme Q10, Omega-3, Glutathione, Coffee Enema, Ozone Therapy, and Finnish Sauna. Their relevance to this marker is therefore indirect, and the strength and type of supporting evidence differ across the interventions.

The findings should not be treated as interchangeable: a measured change in Alanine Aminotransferase is more direct than an improvement in liver fat, liver health, or a proposed detoxification-related effect. Study populations also varied, including generally unspecified health statuses and some clinical-condition settings, so applicability depends on the context and any underlying medical condition.

Diatelos provides general wellness information based on published research. It is not medical advice. Talk to a clinician before starting any new supplement or practice, especially if you have a health condition, are pregnant, or take medication.